2QNF
| Crystal structure of T4 Endonuclease VII H43N mutant in complex with heteroduplex DNA containing base mismatches | Descriptor: | DNA (5'-D(*DCP*DAP*DCP*DAP*DTP*DCP*DGP*DAP*DTP*DGP*DGP*DAP*DGP*DCP*DCP*DG)-3'), DNA (5'-D(*DCP*DAP*DCP*DAP*DTP*DCP*DGP*DAP*DTP*DGP*DGP*DAP*DGP*DCP*DGP*DC)-3'), DNA (5'-D(*DCP*DGP*DGP*DCP*DTP*DCP*DCP*DAP*DTP*DCP*DGP*DAP*DTP*DGP*DTP*DG)-3'), ... | Authors: | Biertumpfel, C, Yang, W, Suck, D. | Deposit date: | 2007-07-18 | Release date: | 2008-01-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of T4 endonuclease VII resolving a Holliday junction. Nature, 449, 2007
|
|
1XQV
| Crystal structure of inactive F1-mutant G37A | Descriptor: | Proline iminopeptidase | Authors: | Goettig, P, Brandstetter, H, Groll, M, Goehring, W, Konarev, P.V, Svergun, D.I, Huber, R, Kim, J.-S. | Deposit date: | 2004-10-13 | Release date: | 2005-07-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum J.Biol.Chem., 280, 2005
|
|
1XR6
| Crystal Structure of RNA-dependent RNA Polymerase 3D from human rhinovirus serotype 1B | Descriptor: | Genome polyprotein, POTASSIUM ION | Authors: | Love, R.A, Maegley, K.A, Yu, X, Ferre, R.A, Lingardo, L.K, Diehl, W, Parge, H.E, Dragovich, P.S, Fuhrman, S.A. | Deposit date: | 2004-10-13 | Release date: | 2004-10-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The Crystal Structure of the RNA-Dependent RNA Polymerase from Human Rhinovirus: A Dual-Function Target for Common Cold Antiviral Therapy Structure, 12, 2004
|
|
1XRL
| Crystal structure of active site F1-mutant Y205F complex with inhibitor PCK | Descriptor: | (2R,3S)-3-AMINO-1-CHLORO-4-PHENYL-BUTAN-2-OL, Proline iminopeptidase | Authors: | Goettig, P, Brandstetter, H, Groll, M, Goehring, W, Konarev, P.V, Svergun, D.I, Huber, R, Kim, J.-S. | Deposit date: | 2004-10-15 | Release date: | 2005-07-12 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum J.Biol.Chem., 280, 2005
|
|
1XRX
| Crystal structure of a DNA-binding protein | Descriptor: | CALCIUM ION, SeqA protein | Authors: | Guarne, A, Brendler, T, Zhao, Q, Ghirlando, R, Austin, S, Yang, W. | Deposit date: | 2004-10-16 | Release date: | 2005-05-10 | Last modified: | 2013-03-06 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structure of a SeqA-N filament: implications for DNA replication and chromosome organization. Embo J., 24, 2005
|
|
3GMA
| Glutaconyl-coA decarboxylase A subunit from Clostridium symbiosum co-crystallized with glutaryl-CoA | Descriptor: | Glutaconyl-CoA decarboxylase subunit A, glutaryl-coenzyme A | Authors: | Kress, D, Brugel, D, Buckel, W, Essen, L.-O. | Deposit date: | 2009-03-13 | Release date: | 2009-07-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | An asymmetric model for Na+-translocating glutaconyl-CoA decarboxylases J.Biol.Chem., 284, 2009
|
|
1EZT
| HIGH-RESOLUTION SOLUTION STRUCTURE OF FREE RGS4 BY NMR | Descriptor: | REGULATOR OF G-PROTEIN SIGNALING 4 | Authors: | Moy, F.J, Chanda, P.K, Cockett, M.I, Edris, W, Jones, P.G, Mason, K, Semus, S, Powers, R. | Deposit date: | 2000-05-11 | Release date: | 2001-01-15 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR structure of free RGS4 reveals an induced conformational change upon binding Galpha. Biochemistry, 39, 2000
|
|
3GOS
| The crystal structure of 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase from Yersinia pestis CO92 | Descriptor: | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, MAGNESIUM ION | Authors: | Zhang, R, Maltseva, N, Kwon, K, Anderson, W, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2009-03-19 | Release date: | 2009-05-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The crystal structure of 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase from Yersinia pestis CO92 To be Published
|
|
2QTA
| |
1YSX
| Solution structure of domain 3 from human serum albumin complexed to an anti-apoptotic ligand directed against Bcl-xL and Bcl-2 | Descriptor: | 4-({2-[(2,4-DIMETHYLPHENYL)SULFANYL]ETHYL}AMINO)-N-[(4'-FLUORO-1,1'-BIPHENYL-4-YL)CARBONYL]-3-NITROBENZENESULFONAMIDE, Serum albumin | Authors: | Oltersdorf, T, Elmore, S.W, Shoemaker, A.R, Armstrong, R.C, Augeri, D.J, Belli, B.A, Bruncko, M, Deckwerth, T.L, Dinges, J, Hajduk, P.J, Joseph, M.K, Kitada, S, Korsmeyer, S.J, Kunzer, A.R, Letai, A, Li, C, Mitten, M.J, Nettesheim, D.G, Ng, S, Nimmer, P.M, O'Connor, J.M, Oleksijew, A, Petros, A.M, Reed, J.C, Shen, W, Tahir, S.K, Thompson, C.B, Tomaselli, K.J, Wang, B, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H. | Deposit date: | 2005-02-09 | Release date: | 2005-06-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | An inhibitor of Bcl-2 family proteins induces regression of solid tumours Nature, 435, 2005
|
|
3GR4
| Activator-Bound Structure of Human Pyruvate Kinase M2 | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, 1-[(2,6-difluorophenyl)sulfonyl]-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Hong, B, Dimov, S, Tempel, W, Auld, D, Thomas, C, Boxer, M, Jianq, J.-K, Skoumbourdis, A, Min, S, Southall, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Inglese, J, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-03-24 | Release date: | 2009-04-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Activator-Bound Structures of Human Pyruvate Kinase M2 to be published
|
|
1YSM
| NMR Structure of N-terminal domain (Residues 1-77) of Siah-Interacting Protein. | Descriptor: | Calcyclin-binding protein | Authors: | Bhattacharya, S, Lee, Y.T, Michowski, W, Jastrzebska, B, Filipek, A, Kuznicki, J, Chazin, W.J. | Deposit date: | 2005-02-08 | Release date: | 2005-07-26 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The Modular Structure of SIP Facilitates Its Role in Stabilizing Multiprotein Assemblies. Biochemistry, 44, 2005
|
|
1EZY
| HIGH-RESOLUTION SOLUTION STRUCTURE OF FREE RGS4 BY NMR | Descriptor: | REGULATOR OF G-PROTEIN SIGNALING 4 | Authors: | Moy, F.J, Chanda, P.K, Cockett, M.I, Edris, W, Jones, P.G, Mason, K, Semus, S, Powers, R. | Deposit date: | 2000-05-12 | Release date: | 2001-01-15 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR structure of free RGS4 reveals an induced conformational change upon binding Galpha. Biochemistry, 39, 2000
|
|
7XQK
| The Crystal Structure of CDK3 and CyclinE1 Complex from Biortus. | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, G1/S-specific cyclin-E1, GLYCEROL, ... | Authors: | Gui, W, Wang, F, Cheng, W, Gao, J, Huang, Y. | Deposit date: | 2022-05-07 | Release date: | 2023-05-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | The Crystal Structure of CDK3 and CyclinE1 Complex from Biortus. To Be Published
|
|
1YOM
| Crystal structure of Src kinase domain in complex with Purvalanol A | Descriptor: | 2-({6-[(3-CHLOROPHENYL)AMINO]-9-ISOPROPYL-9H-PURIN-2-YL}AMINO)-3-METHYLBUTAN-1-OL, Proto-oncogene tyrosine-protein kinase Src | Authors: | Breitenlechner, C.B, Kairies, N.A, Honold, K, Scheiblich, S, Koll, H, Greiter, E, Koch, S, Schaefer, W, Huber, R, Engh, R.A. | Deposit date: | 2005-01-27 | Release date: | 2006-01-27 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structures of active SRC kinase domain complexes J.Mol.Biol., 353, 2005
|
|
1YQK
| Human 8-oxoguanine glycosylase crosslinked with guanine containing DNA | Descriptor: | 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*G)-3', 5'-D(P*CP*AP*GP*GP*TP*CP*TP*AP*C)-3', CALCIUM ION, ... | Authors: | Banerjee, A, Yang, W, Karplus, M, Verdine, G.L. | Deposit date: | 2005-02-01 | Release date: | 2005-04-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA. Nature, 434, 2005
|
|
1YQR
| Catalytically inactive human 8-oxoguanine glycosylase crosslinked to oxoG containing DNA | Descriptor: | 5'-D(P*CP*GP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(P*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3', CALCIUM ION, ... | Authors: | Banerjee, A, Yang, W, Karplus, M, Verdine, G.L. | Deposit date: | 2005-02-02 | Release date: | 2005-04-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA. Nature, 434, 2005
|
|
1YN6
| Crystal structure of a mouse MHC class I protein, H2-Db, in complex with a peptide from the influenza A acid polymerase | Descriptor: | 10-mer peptide from RNA-directed RNA polymerase subunit P2, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | Authors: | Turner, S.J, Kedzierska, K, Komodromou, H, La Gruta, N.L, Dunstone, M.A, Webb, A.I, Webby, R, Walden, H, Xie, W, McCluskey, J, Purcell, A.W, Rossjohn, J, Doherty, P.C. | Deposit date: | 2005-01-23 | Release date: | 2005-06-28 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations Nat.Immunol., 6, 2005
|
|
3H0E
| 3,4-Dihydropyrimido(1,2-a)indol-10(2H)-ones as Potent Non-Peptidic Inhibitors of Caspase-3 | Descriptor: | (10S)-3,3-dimethyl-8-{[(2S)-2-(phenoxymethyl)pyrrolidin-1-yl]sulfonyl}-2,3,4,10-tetrahydropyrimido[1,2-a]indol-10-ol, Caspase-3 | Authors: | Xu, W. | Deposit date: | 2009-04-09 | Release date: | 2009-11-17 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.997 Å) | Cite: | 3,4-Dihydropyrimido(1,2-a)indol-10(2H)-ones as potent non-peptidic inhibitors of caspase-3 Bioorg.Med.Chem., 17, 2009
|
|
3H0R
| Structure of trna-dependent amidotransferase gatcab from aquifex aeolicus | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ASPARAGINE, ... | Authors: | Wu, J, Bu, W, Sheppard, K, Kitabatake, M, Soll, D, Smith, J.L. | Deposit date: | 2009-04-10 | Release date: | 2009-07-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Insights into tRNA-Dependent Amidotransferase Evolution and Catalysis from the Structure of the Aquifex aeolicus Enzyme J.Mol.Biol., 391, 2009
|
|
1YOP
| The solution structure of Kti11p | Descriptor: | Kti11p, ZINC ION | Authors: | Sun, J, Zhang, J, Wu, F, Xu, C, Li, S, Zhao, W, Wu, Z, Wu, J, Zhou, C.-Z, Shi, Y. | Deposit date: | 2005-01-28 | Release date: | 2005-04-05 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of Kti11p from Saccharomyces cerevisiae reveals a novel zinc-binding module. Biochemistry, 44, 2005
|
|
2WBI
| Crystal structure of human acyl-CoA dehydrogenase 11 | Descriptor: | ACYL-COA DEHYDROGENASE FAMILY MEMBER 11, FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATE ION, ... | Authors: | Muniz, J.R.C, Guo, K, Savitsky, P, Roos, A, Yue, W, Pilka, E, von Delft, F, Edwards, A.M, Bountra, C, Arrowsmith, C.H, Weigelt, J, Oppermann, U. | Deposit date: | 2009-02-28 | Release date: | 2009-05-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of Human Acyl-Coa Dehydrogenase 11 To be Published
|
|
3GQY
| Activator-Bound Structure of Human Pyruvate Kinase M2 | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, 1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[(4-methoxyphenyl)sulfonyl]piperazine, L(+)-TARTARIC ACID, ... | Authors: | Hong, B, Dimov, S, Tempel, W, Auld, D, Thomas, C, Boxer, M, Jianq, J.-K, Skoumbourdis, A, Min, S, Southall, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Inglese, J, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-03-24 | Release date: | 2009-04-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Activator-Bound Structures of Human Pyruvate Kinase M2 to be published
|
|
1BSJ
| COBALT DEFORMYLASE INHIBITOR COMPLEX FROM E.COLI | Descriptor: | (S)-2-(PHOSPHONOXY)CAPROYL-L-LEUCYL-P-NITROANILIDE, COBALT (II) ION, PHOSPHATE ION, ... | Authors: | Hao, B, Gong, W, Rajagopalan, P.T, Hu, Y, Pei, D, Chan, M.K. | Deposit date: | 1998-08-28 | Release date: | 2000-04-15 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for the design of antibiotics targeting peptide deformylase. Biochemistry, 38, 1999
|
|
1YQL
| Catalytically inactive hOGG1 crosslinked with 7-deaza-8-azaguanine containing DNA | Descriptor: | 5'-D(P*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*CP*AP*(PPW)P*GP*TP*CP*TP*AP*C)-3', CALCIUM ION, ... | Authors: | Banerjee, A, Yang, W, Karplus, M, Verdine, G.L. | Deposit date: | 2005-02-02 | Release date: | 2005-04-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA. Nature, 434, 2005
|
|