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PDB: 12920 results

5KFS
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BU of 5kfs by Molmil
Human DNA polymerase eta R61A-DNA ternary complex: ground state at pH7.0 (K+ MES) with 1 Ca2+ ion
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
1ID9
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BU of 1id9 by Molmil
STRUCTURE OF THE HYBRID RNA/DNA R-GCUUCGGC-D[F]U IN PRESENCE OF RH(NH3)6+++
Descriptor: 5'-R(*GP*CP*UP*UP*CP*GP*GP*C)-D(P*(UFP))-3', CHLORIDE ION, RHODIUM HEXAMINE ION
Authors:Cruse, W, Saludjian, P, Neuman, A, Prange, T.
Deposit date:2001-04-04
Release date:2001-04-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Destabilizing effect of a fluorouracil extra base in a hybrid RNA duplex compared with bromo and chloro analogues.
Acta Crystallogr.,Sect.D, 57, 2001
5KG3
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BU of 5kg3 by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 10 mM Mn2+ for 60s
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFF
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BU of 5kff by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction with 1 mM Mn2+ for 1800s
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
6NJE
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BU of 6nje by Molmil
Crystal structure of the motor domain of human kinesin family member 22
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Kinesin-like protein KIF22, ...
Authors:Walker, B.C, Zhu, H, Tempel, W, Arrowsmith, C.H, Edwards, A.M, Park, H, Cochran, J.C, Structural Genomics Consortium (SGC)
Deposit date:2019-01-03
Release date:2019-01-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the motor domain of human kinesin family member 22
To Be Published
5KFQ
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BU of 5kfq by Molmil
Human DNA polymerase eta-DNA ternary complex with Sp-dATP-alpha-S: reaction with 10 mM Mn2+ for 600s
Descriptor: 2'-DEOXYADENOSINE 5'-O-(1-THIOTRIPHOSPHATE), CALCIUM ION, DIPHOSPHATE, ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KG2
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BU of 5kg2 by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 5 mM Mn2+ for 60s at 37 degree
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
6NYF
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BU of 6nyf by Molmil
Helicobacter pylori Vacuolating Cytotoxin A Oligomeric Assembly 1 (OA-1)
Descriptor: Vacuolating cytotoxin autotransporter
Authors:Zhang, K, Zhang, H, Li, S, Au, S, Chiu, W.
Deposit date:2019-02-11
Release date:2019-03-27
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures ofHelicobacter pylorivacuolating cytotoxin A oligomeric assemblies at near-atomic resolution.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
5CZG
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BU of 5czg by Molmil
Crystal Structure Analysis of hypothetical bromodomain Tb427.10.7420 from Trypanosoma brucei in complex with bromosporine
Descriptor: Bromosporine, Hypothetical Bromodomain, SODIUM ION, ...
Authors:Jiang, D.Q, Tempel, W, Loppnau, P, Graslund, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hui, R, Amani, M, Hou, C.F.D, Structural Genomics Consortium (SGC)
Deposit date:2015-07-31
Release date:2015-08-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.451 Å)
Cite:Crystal Structure Analysis of hypothetical bromodomain from Trypanosoma brucei
to be published
5DJ5
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BU of 5dj5 by Molmil
Crystal structure of rice DWARF14 in complex with synthetic strigolactone GR24
Descriptor: (3E,3aR,8bS)-3-({[(2R)-4-methyl-5-oxo-2,5-dihydrofuran-2-yl]oxy}methylidene)-3,3a,4,8b-tetrahydro-2H-indeno[1,2-b]furan-2-one, Probable strigolactone esterase D14
Authors:Zhou, X.E, Zhao, L.-H, Yi, W, Wu, Z.-S, Liu, Y, Kang, Y, Hou, L, de Waal, P.W, Li, S, Jiang, Y, Melcher, K, Xu, H.E.
Deposit date:2015-09-01
Release date:2015-10-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Destabilization of strigolactone receptor DWARF14 by binding of ligand and E3-ligase signaling effector DWARF3.
Cell Res., 25, 2015
6O0V
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BU of 6o0v by Molmil
Crystal structure of the TIR domain G601P mutant from human SARM1, crystal form 2
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Sterile alpha and TIR motif-containing protein 1
Authors:Horsefield, S, Burdett, H, Zhang, X, Manik, M.K, Shi, Y, Chen, J, Tiancong, Q, Gilley, J, Lai, J, Gu, W, Rank, M, Casey, L, Ericsson, D.J, Foley, G, Hughes, R.O, Bosanac, T, von Itzstein, M, Rathjen, J.P, Nanson, J.D, Boden, M, Dry, I.B, Williams, S.J, Staskawicz, B.J, Coleman, M.P, Ve, T, Dodds, P.N, Kobe, B.
Deposit date:2019-02-17
Release date:2019-09-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:NAD+cleavage activity by animal and plant TIR domains in cell death pathways.
Science, 365, 2019
1IAR
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BU of 1iar by Molmil
INTERLEUKIN-4 / RECEPTOR ALPHA CHAIN COMPLEX
Descriptor: PROTEIN (INTERLEUKIN-4 RECEPTOR ALPHA CHAIN), PROTEIN (INTERLEUKIN-4)
Authors:Hage, T, Sebald, W, Reinemer, P.
Deposit date:1999-02-25
Release date:2000-03-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the interleukin-4/receptor alpha chain complex reveals a mosaic binding interface.
Cell(Cambridge,Mass.), 97, 1999
5KFB
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BU of 5kfb by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction with 1 mM Mn2+ for 90s
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFM
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BU of 5kfm by Molmil
Human DNA polymerase eta-DNA ternary complex with Sp-dATP-alpha-S: ground state at pH7.0 (K+ MES) with 1 Ca2+ ion
Descriptor: 2'-DEOXYADENOSINE 5'-O-(1-THIOTRIPHOSPHATE), CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFW
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BU of 5kfw by Molmil
Human DNA polymerase eta R61A-DNA ternary complex: reaction with 1 mM Mg2+ for 200s
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5D48
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BU of 5d48 by Molmil
Crystal Structure of FABP4 in complex with 3-{5-cyclopropyl-3-(3,5-dimethyl-1H-pyrazol-4-yl)-2-[3-(propan-2-yloxy) phenyl]-1H-indol-1-yl}propanoic acid
Descriptor: 3-{5-cyclopropyl-3-(3,5-dimethyl-1H-pyrazol-4-yl)-2-[3-(propan-2-yloxy)phenyl]-1H-indol-1-yl}propanoic acid, Fatty acid-binding protein, adipocyte, ...
Authors:Tagami, U, Takahashi, K, Igarashi, S, Ejima, C, Yoshida, T, Takeshita, S, Miyanaga, W, Sugiki, M, Tokumasu, M, Hatanaka, T, Kashiwagi, T, Ishikawa, K, Miyano, H, Mizukoshi, T.
Deposit date:2015-08-07
Release date:2016-06-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Interaction Analysis of FABP4 Inhibitors by X-ray Crystallography and Fragment Molecular Orbital Analysis
Acs Med.Chem.Lett., 7, 2016
5KFI
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BU of 5kfi by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction with 10 mM Mn2+ for 120s
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFT
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BU of 5kft by Molmil
Human DNA polymerase eta R61A-DNA ternary complex: reaction with 1 mM Mg2+ for 40s
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KG5
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BU of 5kg5 by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 10 mM Cd2+ for 60s
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
1NR2
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BU of 1nr2 by Molmil
High resolution crystal structures of thymus and activation-regulated chemokine
Descriptor: Thymus and activation-regulated chemokine
Authors:Asojo, O.A, Boulegue, C, Hoover, D.M, Lu, W, Lubkowski, J.
Deposit date:2003-01-23
Release date:2003-08-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Structures of thymus and activation-regulated chemokine (TARC).
Acta Crystallogr.,Sect.D, 59, 2003
8QMO
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BU of 8qmo by Molmil
Cryo-EM structure of the benzo[a]pyrene-bound Hsp90-XAP2-AHR complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, Aryl hydrocarbon receptor, ...
Authors:Kwong, H.S, Grandvuillemin, L, Sirounian, S, Ancelin, A, Lai-Kee-Him, J, Carivenc, C, Lancey, C, Ragan, T.J, Hesketh, E.L, Bourguet, W, Gruszczyk, J.
Deposit date:2023-09-24
Release date:2024-01-10
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Structural Insights into the Activation of Human Aryl Hydrocarbon Receptor by the Environmental Contaminant Benzo[a]pyrene and Structurally Related Compounds.
J.Mol.Biol., 436, 2024
6O0S
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BU of 6o0s by Molmil
Crystal structure of the tandem SAM domains from human SARM1
Descriptor: Sterile alpha and TIR motif-containing protein 1
Authors:Horsefield, S, Burdett, H, Zhang, X, Manik, M.K, Shi, Y, Chen, J, Tiancong, Q, Gilley, J, Lai, J, Gu, W, Rank, M, Deerain, N, Casey, L, Ericsson, D.J, Foley, G, Hughes, R.O, Bosanac, T, von Itzstein, M, Rathjen, J.P, Nanson, J.D, Boden, M, Dry, I.B, Williams, S.J, Staskawicz, B.J, Coleman, M.P, Ve, T, Dodds, P.N, Kobe, B.
Deposit date:2019-02-17
Release date:2019-09-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:NAD+cleavage activity by animal and plant TIR domains in cell death pathways.
Science, 365, 2019
8IL0
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BU of 8il0 by Molmil
Crystal structure of LmbT from Streptomyces lincolnensis NRRL ISP-5355
Descriptor: Glycosyltransferase
Authors:Dai, Y, Li, P, Qiao, H, Xia, M, Liu, W, Fang, P.
Deposit date:2023-03-01
Release date:2023-09-20
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structural Basis of Low-Molecular-Weight Thiol Glycosylation in Lincomycin A Biosynthesis.
Acs Chem.Biol., 18, 2023
8ILA
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BU of 8ila by Molmil
Crystal structure of LmbT from Streptomyces lincolnensis NRRL ISP-5355 in complex with substrates
Descriptor: (2~{S})-3-[2-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-[(1~{R},2~{R})-1-azanyl-2-oxidanyl-propyl]-3,4,5-tris(oxidanyl)oxan-2-yl]sulfanyl-1~{H}-imidazol-5-yl]-2-(trimethyl-$l^{4}-azanyl)propanoic acid, GUANOSINE-5'-DIPHOSPHATE, Glycosyltransferase
Authors:Dai, Y, Qiao, H, Xia, M, Fang, P, Liu, W.
Deposit date:2023-03-03
Release date:2023-09-20
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structural Basis of Low-Molecular-Weight Thiol Glycosylation in Lincomycin A Biosynthesis.
Acs Chem.Biol., 18, 2023
8EHW
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BU of 8ehw by Molmil
cryo-EM structure of TMEM63A in nanodisc
Descriptor: CSC1-like protein 1
Authors:Zheng, W, Fu, T.M, Holt, J.R.
Deposit date:2022-09-14
Release date:2023-08-23
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:TMEM63 proteins function as monomeric high-threshold mechanosensitive ion channels.
Neuron, 111, 2023

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