2IDZ
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![BU of 2idz by Molmil](/molmil-images/mine/2idz) | Crystal structure of wild type Enoyl-ACP(CoA) reductase from Mycobacterium tuberculosis in complex with NADH-INH | Descriptor: | Enoyl-[acyl-carrier-protein] reductase [NADH], ISONICOTINIC-ACETYL-NICOTINAMIDE-ADENINE DINUCLEOTIDE | Authors: | Dias, M.V.B, Prado, M.P.X, Vasconcelos, I.B, Valmir, F, Basso, L.A, Santos, D.S, Azevedo Jr, W.F. | Deposit date: | 2006-09-15 | Release date: | 2007-07-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystallographic studies on the binding of isonicotinyl-NAD adduct to wild-type and isoniazid resistant 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis. J.Struct.Biol., 159, 2007
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2IE0
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![BU of 2ie0 by Molmil](/molmil-images/mine/2ie0) | Crystal Structure of Isoniazid-resistant I21V Enoyl-ACP(COA) Reductase Mutant Enzyme From MYCOBACTERIUM TUBERCULOSIS in Complex with NADH-INH | Descriptor: | Enoyl-[acyl-carrier-protein] reductase [NADH], ISONICOTINIC-ACETYL-NICOTINAMIDE-ADENINE DINUCLEOTIDE | Authors: | Dias, M.V.B, Prado, A.M.X, Vasconceles, I.B, Fadel, F, Basso, L.A, Santos, D.S, Azevedo Jr, W.F. | Deposit date: | 2006-09-15 | Release date: | 2007-07-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystallographic studies on the binding of isonicotinyl-NAD adduct to wild-type and isoniazid resistant 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis. J.Struct.Biol., 159, 2007
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2IEB
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![BU of 2ieb by Molmil](/molmil-images/mine/2ieb) | Crystal Structure of Isoniazid-resistant S94A ENOYL-ACP(COA) Reductase Mutant Enzyme from MYCOBACTERIUM TUBERCULOSIS in Complex with NADH-INH | Descriptor: | Enoyl-[acyl-carrier-protein] reductase [NADH], ISONICOTINIC-ACETYL-NICOTINAMIDE-ADENINE DINUCLEOTIDE | Authors: | Dias, M.V.B, Prado, A.M.X, Vasconcelos, I.B, Fadel, V, Basso, L.A, Santos, D.S, Azevedo Jr, W.F. | Deposit date: | 2006-09-18 | Release date: | 2007-07-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystallographic studies on the binding of isonicotinyl-NAD adduct to wild-type and isoniazid resistant 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis. J.Struct.Biol., 159, 2007
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2IED
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![BU of 2ied by Molmil](/molmil-images/mine/2ied) | CRYSTAL STRUCTURE of ISONIAZID-RESISTANT S94A ENOYL-ACP(COA) REDUCTASE MUTANT ENZYME FROM MYCOBACTERIUM TUBERCULOSIS UNCOMPLEXED | Descriptor: | Enoyl-[acyl-carrier-protein] reductase [NADH] | Authors: | Dias, M.V.B, Prado, A.M.X, Vasconcelos, I.B, Fadel, V, Basso, L.A, Santos, D.S, Azevedo Jr, W.F. | Deposit date: | 2006-09-18 | Release date: | 2007-07-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Crystallographic studies on the binding of isonicotinyl-NAD adduct to wild-type and isoniazid resistant 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis. J.Struct.Biol., 159, 2007
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6XZT
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![BU of 6xzt by Molmil](/molmil-images/mine/6xzt) | Crystal structure of helicase Pif1 from Thermus oshimai mutant G110C-E410C | Descriptor: | PIF1 helicase | Authors: | Dai, Y.X, Chen, W.F, Teng, F.Y, Liu, N.N, Hou, X.M, Dou, S.X, Rety, S, Xi, X.G. | Deposit date: | 2020-02-05 | Release date: | 2021-02-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.341 Å) | Cite: | Structural and functional studies of SF1B Pif1 from Thermus oshimai reveal dimerization-induced helicase inhibition. Nucleic Acids Res., 49, 2021
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6YB1
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![BU of 6yb1 by Molmil](/molmil-images/mine/6yb1) | Crystal structure of an antiparallel octameric transmembrane coiled coil K2-CCTM-VbIc | Descriptor: | GLYCINE, K2-CCTM-VbIc, NONAETHYLENE GLYCOL | Authors: | Kratochvil, H.T, Liu, L, Scott, A.J, Woolfson, D.N, DeGrado, W.F. | Deposit date: | 2020-03-15 | Release date: | 2021-04-07 | Last modified: | 2021-07-14 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Constructing ion channels from water-soluble alpha-helical barrels. Nat.Chem., 13, 2021
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3BAF
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![BU of 3baf by Molmil](/molmil-images/mine/3baf) | Crystal structure of shikimate kinase from Mycobacterium tuberculosis in complex with AMP-PNP | Descriptor: | (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Shikimate kinase | Authors: | Faim, L.M, Dias, M.V.B, Vasconcelos, I.G, Basso, L.A, Santos, D.S, Azevedo, W.F, Ruggiero, N.J. | Deposit date: | 2007-11-07 | Release date: | 2008-11-11 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal Structure for shikimate kinase from Mycobacterium tuberculosis in complex with AMP-PNP To be Published
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6Z0L
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![BU of 6z0l by Molmil](/molmil-images/mine/6z0l) | Het-N2 - De novo designed three-helix heterodimer with Cysteine at the N2 position of the alpha-helix | Descriptor: | CADMIUM ION, Cys-N2 Strand, Positive Strand, ... | Authors: | McEwen, A.G, Poussin-Courmontagne, P, Naudin, E.A, DeGrado, W.F, Torbeev, V. | Deposit date: | 2020-05-09 | Release date: | 2021-03-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Acyl Transfer Catalytic Activity in De Novo Designed Protein with N-Terminus of alpha-Helix As Oxyanion-Binding Site. J.Am.Chem.Soc., 143, 2021
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6Z0M
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![BU of 6z0m by Molmil](/molmil-images/mine/6z0m) | Het-Ncap - De novo designed three-helix heterodimer with Cysteine at the Ncap position of the alpha-helix | Descriptor: | Cys-Ncap strand, Positive Strand, SULFATE ION, ... | Authors: | McEwen, A.G, Poussin-Courmontagne, P, Naudin, E.A, DeGrado, W.F, Torbeev, V. | Deposit date: | 2020-05-09 | Release date: | 2021-03-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Acyl Transfer Catalytic Activity in De Novo Designed Protein with N-Terminus of alpha-Helix As Oxyanion-Binding Site. J.Am.Chem.Soc., 143, 2021
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6ZD2
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![BU of 6zd2 by Molmil](/molmil-images/mine/6zd2) | Structure of apo telomerase from Candida Tropicalis truncated from C-terminal domain | Descriptor: | SODIUM ION, Telomerase reverse transcriptase | Authors: | Zhai, L, Rety, S, Chen, W.F, Auguin, D, Xi, X.G. | Deposit date: | 2020-06-13 | Release date: | 2021-04-28 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi‡. Nucleic Acids Res., 49, 2021
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6ZDQ
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![BU of 6zdq by Molmil](/molmil-images/mine/6zdq) | Structure of telomerase from Candida albicans in complexe with TWJ fragment of telomeric RNA | Descriptor: | RNA, Telomerase reverse transcriptase | Authors: | Zhai, L, Rety, S, Chen, W.F, Auguin, D, Xi, X.G. | Deposit date: | 2020-06-15 | Release date: | 2021-04-28 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi‡. Nucleic Acids Res., 49, 2021
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6ZD1
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![BU of 6zd1 by Molmil](/molmil-images/mine/6zd1) | Structure of apo telomerase from Candida Tropicalis | Descriptor: | Telomerase reverse transcriptase | Authors: | Zhai, L, Rety, S, Chen, W.F, Auguin, D, Xi, X.G. | Deposit date: | 2020-06-13 | Release date: | 2021-04-28 | Last modified: | 2021-05-12 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi‡. Nucleic Acids Res., 49, 2021
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6ZD6
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![BU of 6zd6 by Molmil](/molmil-images/mine/6zd6) | Structure of apo telomerase from Candida Tropicalis | Descriptor: | Telomerase reverse transcriptase | Authors: | Zhai, L, Rety, S, Chen, W.F, Auguin, D, Xi, X.G. | Deposit date: | 2020-06-13 | Release date: | 2021-04-28 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi‡. Nucleic Acids Res., 49, 2021
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6ZDU
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![BU of 6zdu by Molmil](/molmil-images/mine/6zdu) | Structure of telomerase from Candida albicans in complexe with TWJ fragment of telomeric RNA | Descriptor: | Chains: C,D, Telomerase reverse transcriptase | Authors: | Zhai, L, Rety, S, Chen, W.F, Auguin, D, Xi, X.G. | Deposit date: | 2020-06-15 | Release date: | 2021-04-28 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.45 Å) | Cite: | Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi‡. Nucleic Acids Res., 49, 2021
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6ZDP
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![BU of 6zdp by Molmil](/molmil-images/mine/6zdp) | Structure of telomerase from Candida Tropicalis in complexe with TWJ fragment of telomeric RNA | Descriptor: | Chains: B, POTASSIUM ION, Telomerase reverse transcriptase | Authors: | Zhai, L, Rety, S, Chen, W.F, Auguin, D, Xi, X.G. | Deposit date: | 2020-06-15 | Release date: | 2021-04-28 | Last modified: | 2021-05-12 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi‡. Nucleic Acids Res., 49, 2021
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3BV6
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![BU of 3bv6 by Molmil](/molmil-images/mine/3bv6) | Crystal structure of uncharacterized metallo protein from Vibrio cholerae with beta-lactamase like fold | Descriptor: | FE (III) ION, Metal-dependent hydrolase | Authors: | Minasov, G, Shuvalova, L, Brunzelle, J.S, Yang, X, Collart, F.R, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2008-01-04 | Release date: | 2008-01-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of uncharacterized metallo protein from Vibrio cholerae with beta-lactamase like fold. To be Published
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3C2S
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![BU of 3c2s by Molmil](/molmil-images/mine/3c2s) | Structural Characterization of a Human Fc Fragment Engineered for Lack of Effector Functions | Descriptor: | IGHM protein, ZINC ION, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Oganesyan, V, Wu, H, Dall'Acqua, W.F. | Deposit date: | 2008-01-25 | Release date: | 2008-08-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural characterization of a human Fc fragment engineered for lack of effector functions. Acta Crystallogr.,Sect.D, 64, 2008
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2ZBJ
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![BU of 2zbj by Molmil](/molmil-images/mine/2zbj) | Crystal structure of Dioclea rostrata lectin | Descriptor: | CALCIUM ION, Lectin alpha chain, MANGANESE (II) ION, ... | Authors: | de Oliveira, T.M, Delatorre, P, da Rocha, B.A.M, de Sousa, E.P, Nascimento, K.S, Bezerra, G.A, Moura, T.R, Benevides, R.G, Bezerra, E.H.S, Moreno, F.B.M.B, Freire, V.N, de Azevedo Jr, W.F, Cavada, B.S. | Deposit date: | 2007-10-22 | Release date: | 2008-08-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal structure of Dioclea rostrata lectin: Insights into understanding the pH-dependent dimer-tetramer equilibrium and the structural basis for carbohydrate recognition in Diocleinae lectins J.Struct.Biol., 164, 2008
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3D4B
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![BU of 3d4b by Molmil](/molmil-images/mine/3d4b) | Crystal structure of Sir2Tm in complex with Acetyl p53 peptide and DADMe-NAD+ | Descriptor: | 5'-O-[(R)-{[(R)-{[(3R,4R)-1-(3-carbamoylbenzyl)-4-hydroxypyrrolidin-3-yl]methoxy}(hydroxy)phosphoryl]methyl}(hydroxy)phosphoryl]adenosine, Acetyl P53 peptide, NAD-dependent deacetylase, ... | Authors: | Hawse, W.F, Hoff, K.G, Fatkins, D, Daines, A, Zubkova, O.V, Schramm, V.L, Zheng, W, Wolberger, C. | Deposit date: | 2008-05-14 | Release date: | 2008-09-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural insights into intermediate steps in the Sir2 deacetylation reaction. Structure, 16, 2008
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3BCQ
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![BU of 3bcq by Molmil](/molmil-images/mine/3bcq) | Crystal structure of oxy-hemoglobin from Brycon cephalus | Descriptor: | Alpha-chain hemoglobin, Beta-chain hemoglobin, OXYGEN MOLECULE, ... | Authors: | Poy, C.D, Leopoldino, A.M, Rahal, P, de Azevedo, W.F, Rodriguez, G.O.B, Murakami, M.T. | Deposit date: | 2007-11-13 | Release date: | 2008-10-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of oxy-hemoglobin from Brycon cephalus To be Published
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3D81
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![BU of 3d81 by Molmil](/molmil-images/mine/3d81) | Sir2-S-alkylamidate complex crystal structure | Descriptor: | NAD-dependent deacetylase, S-alkylamidate intermediate, ZINC ION | Authors: | Hawse, W.F, Hoff, K.G, Fatkins, D, Daines, A, Zubkova, O.V, Schramm, V.L, Zheng, W, Wolberger, C. | Deposit date: | 2008-05-22 | Release date: | 2008-09-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural insights into intermediate steps in the Sir2 deacetylation reaction. Structure, 16, 2008
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3LYL
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![BU of 3lyl by Molmil](/molmil-images/mine/3lyl) | Structure of 3-oxoacyl-acylcarrier protein reductase, FabG from Francisella tularensis | Descriptor: | 3-oxoacyl-(Acyl-carrier-protein) reductase | Authors: | Anderson, S.M, Wawrzak, Z, Gordon, E, Hasseman, J, Edwards, A, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2010-02-27 | Release date: | 2010-03-23 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure of 3-oxoacyl-acylcarrier protein reductase, FabG from Francisella tularensis TO BE PUBLISHED
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3LZ8
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![BU of 3lz8 by Molmil](/molmil-images/mine/3lz8) | Structure of a putative chaperone dnaj from klebsiella pneumoniae subsp. pneumoniae mgh 78578 at 2.9 a resolution. | Descriptor: | Putative chaperone DnaJ | Authors: | Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Bearden, J, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2010-03-01 | Release date: | 2010-03-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of a Putative Chaperone Dnaj from Klebsiella Pneumoniae Subsp. Pneumoniae Mgh 78578 at 2.9 A Resolution. To be Published
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3LXM
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![BU of 3lxm by Molmil](/molmil-images/mine/3lxm) | 2.00 Angstrom resolution crystal structure of a catalytic subunit of an aspartate carbamoyltransferase (pyrB) from Yersinia pestis CO92 | Descriptor: | Aspartate carbamoyltransferase, TETRAETHYLENE GLYCOL | Authors: | Halavaty, A.S, Minasov, G, Dubrovska, I, Winsor, J, Shuvalova, L, Peterson, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2010-02-25 | Release date: | 2010-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | 2.00 Angstrom resolution crystal structure of a catalytic subunit of an aspartate carbamoyltransferase (pyrB) from Yersinia pestis CO92 To be Published
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3LV8
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![BU of 3lv8 by Molmil](/molmil-images/mine/3lv8) | 1.8 Angstrom resolution crystal structure of a thymidylate kinase (tmk) from Vibrio cholerae O1 biovar eltor str. N16961 in complex with TMP, thymidine-5'-diphosphate and ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, CHLORIDE ION, ... | Authors: | Halavaty, A.S, Minasov, G, Dubrovska, I, Winsor, J, Shuvalova, L, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2010-02-19 | Release date: | 2010-03-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | 1.8 Angstrom resolution crystal structure of a thymidylate kinase (tmk) from Vibrio cholerae O1 biovar eltor str. N16961 in complex with TMP, thymidine-5'-diphosphate and ADP To be Published
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