4N7R
| Crystal structure of Arabidopsis glutamyl-tRNA reductase in complex with its binding protein | 分子名称: | Genomic DNA, chromosome 3, P1 clone: MXL8, ... | 著者 | Zhao, A, Fang, Y, Lin, Y, Gong, W, Liu, L. | 登録日 | 2013-10-16 | 公開日 | 2014-05-14 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | 主引用文献 | Crystal structure of Arabidopsis glutamyl-tRNA reductase in complex with its stimulator protein Proc.Natl.Acad.Sci.USA, 111, 2014
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6RV2
| Crystal structure of the human two pore domain potassium ion channel TASK-1 (K2P3.1) in a closed conformation | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, DECYL-BETA-D-MALTOPYRANOSIDE, ... | 著者 | Rodstrom, K.E.J, Pike, A.C.W, Zhang, W, Quigley, A, Speedman, D, Mukhopadhyay, S.M.M, Shrestha, L, Chalk, R, Venkaya, S, Bushell, S.R, Tessitore, A, Burgess-Brown, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2019-05-30 | 公開日 | 2019-08-07 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | A lower X-gate in TASK channels traps inhibitors within the vestibule. Nature, 582, 2020
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6S0T
| The crystal structure of kanamycin B dioxygenase (KanJ) from Streptomyces kanamyceticus in complex with nickel, sulfate, soaked with iodide | 分子名称: | IODIDE ION, Kanamycin B dioxygenase, NICKEL (II) ION, ... | 著者 | Mrugala, B, Porebski, P.J, Niedzialkowska, E, Cymborowski, M.T, Minor, W, Borowski, T. | 登録日 | 2019-06-18 | 公開日 | 2020-07-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A study on the structure, mechanism, and biochemistry of kanamycin B dioxygenase (KanJ)-an enzyme with a broad range of substrates. Febs J., 288, 2021
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6YGV
| tRNA-Guanine Transglycosylase (TGT) in co-crystallized complex with (E)-N-ethyl-4-oxo-4-phenylbut-2-enamide | 分子名称: | GLYCEROL, Queuine tRNA-ribosyltransferase, ZINC ION, ... | 著者 | Nguyen, A, Heyder, L, Heine, A, Diederich, W, Klebe, G. | 登録日 | 2020-03-27 | 公開日 | 2020-04-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Ligands disturb dimer contacts To Be Published
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5CE7
| Structure of a non-canonical CID of Ctk3 | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CTD kinase subunit gamma | 著者 | Muehlbacher, W, Mayer, A, Sun, M, Remmert, M, Cheung, A.C, Niesser, J, Soeding, J, Cramer, P. | 登録日 | 2015-07-06 | 公開日 | 2015-08-05 | 最終更新日 | 2015-09-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of Ctk3, a subunit of the RNA polymerase II CTD kinase complex, reveals a noncanonical CTD-interacting domain fold. Proteins, 83, 2015
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6S5J
| Strictosidine Synthase from Ophiorrhiza pumila in complex with (S)-1-Ethyl-2,3,4,9-tetrahydro-1H-beta-carboline | 分子名称: | (1~{S})-1-ethyl-2,3,4,9-tetrahydro-1~{H}-pyrido[3,4-b]indole, Strictosidine synthase | 著者 | Eger, E, Sharma, M, Kroutil, W, Grogan, G. | 登録日 | 2019-07-01 | 公開日 | 2020-04-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Inverted Binding of Non-natural Substrates in Strictosidine Synthase Leads to a Switch of Stereochemical Outcome in Enzyme-Catalyzed Pictet-Spengler Reactions. J.Am.Chem.Soc., 142, 2020
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6S5Q
| Strictosidine Synthase from Ophiorrhiza pumila in complex with (S)-1-isobutyl-2,3,4,9-tetrahydro-1H-beta-carboline | 分子名称: | (1~{S})-1-(2-methylpropyl)-2,3,4,9-tetrahydro-1~{H}-pyrido[3,4-b]indole, Strictosidine synthase | 著者 | Eger, E, Sharma, M, Kroutil, W, Grogan, G. | 登録日 | 2019-07-02 | 公開日 | 2020-04-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Inverted Binding of Non-natural Substrates in Strictosidine Synthase Leads to a Switch of Stereochemical Outcome in Enzyme-Catalyzed Pictet-Spengler Reactions. J.Am.Chem.Soc., 142, 2020
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6S5U
| Strictosidine Synthase from Ophiorrhiza pumila in complex with N-[2-(1H-Indol-3-yl)ethyl]-3-methyl-1-butanamine | 分子名称: | Strictosidine synthase, ~{N}-[2-(1~{H}-indol-3-yl)ethyl]-3-methyl-butan-1-amine | 著者 | Eger, E, Sharma, M, Kroutil, W, Grogan, G. | 登録日 | 2019-07-02 | 公開日 | 2020-04-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Inverted Binding of Non-natural Substrates in Strictosidine Synthase Leads to a Switch of Stereochemical Outcome in Enzyme-Catalyzed Pictet-Spengler Reactions. J.Am.Chem.Soc., 142, 2020
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6S5M
| Strictosidine Synthase from Ophiorrhiza pumila in complex with (S)-1-n-propyl-2,3,4,9-tetrahydro-1H-beta-carboline | 分子名称: | (1~{S})-1-propyl-2,3,4,9-tetrahydro-1~{H}-pyrido[3,4-b]indole, Strictosidine synthase | 著者 | Eger, E, Sharma, M, Kroutil, W, Grogan, G. | 登録日 | 2019-07-02 | 公開日 | 2020-04-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Inverted Binding of Non-natural Substrates in Strictosidine Synthase Leads to a Switch of Stereochemical Outcome in Enzyme-Catalyzed Pictet-Spengler Reactions. J.Am.Chem.Soc., 142, 2020
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6RLM
| Crystal structure of AT1412dm Fab fragment | 分子名称: | AT1412dm Fab (Heavy Chain), AT1412dm Fab (Light Chain), CHLORIDE ION | 著者 | Neviani, V, Pearce, N.M, Pos, W, Schotte, R, Spits, H, Gros, P. | 登録日 | 2019-05-02 | 公開日 | 2021-05-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis of a homo-dimerization site in tetraspanin CD9 targeted by a melanoma patient-derived antibody To Be Published
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6RLO
| Crystal structure of AT1412dm Fab fragment in complex with CD9 large extracellular loop | 分子名称: | AT1412dm Fab Fragment (Heavy Chain), AT1412dm Fab Fragment (Light Chain), CD9 antigen, ... | 著者 | Neviani, V, Pearce, N.M, Pos, W, Schotte, R, Spits, H, Gros, P. | 登録日 | 2019-05-02 | 公開日 | 2021-05-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis of a homo-dimerization site in tetraspanin CD9 targeted by a melanoma patient-derived antibody To Be Published
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6SF3
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4NOM
| Crystal structure of asparaginyl endopeptidase (AEP)/Legumain activated at pH 4.5 | 分子名称: | Legumain | 著者 | Zhao, L, Hua, T, Ru, H, Ni, X, Shaw, N, Jiao, L, Ding, W, Qu, L, Ouyang, S, Liu, Z.J. | 登録日 | 2013-11-19 | 公開日 | 2014-02-19 | 最終更新日 | 2014-03-19 | 実験手法 | X-RAY DIFFRACTION (2.006 Å) | 主引用文献 | Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage. Cell Res., 24, 2014
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6SF2
| Ternary complex of human bone morphogenetic protein 9 (BMP9) growth factor domain, its prodomain and extracellular domain of activin receptor-like kinase 1 (ALK1). | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Growth/differentiation factor 2, Serine/threonine-protein kinase receptor R3 | 著者 | Salmon, R.M, Guo, J, Yu, M, Li, W. | 登録日 | 2019-07-31 | 公開日 | 2020-04-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Molecular basis of ALK1-mediated signalling by BMP9/BMP10 and their prodomain-bound forms. Nat Commun, 11, 2020
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6XV1
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6WBZ
| Structure of Human HDAC2 in complex with an ethyl ketone inhibitor containing a spiro-bicyclic group | 分子名称: | (1S)-N-{(1S)-7,7-dihydroxy-1-[5-(2-methoxyquinolin-3-yl)-1H-imidazol-2-yl]nonyl}-6-ethyl-6-azaspiro[2.5]octane-1-carboxamide, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Klein, D.J, Yu, W. | 登録日 | 2020-03-28 | 公開日 | 2020-05-06 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | 主引用文献 | Discovery of ethyl ketone-based HDACs 1, 2, and 3 selective inhibitors for HIV latency reactivation. Bioorg.Med.Chem.Lett., 30, 2020
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6SF1
| Bone morphogenetic protein 10 (BMP10) complexed with extracellular domain of activin receptor-like kinase 1 (ALK1). | 分子名称: | Bone morphogenetic protein 10, NICKEL (II) ION, Serine/threonine-protein kinase receptor R3 | 著者 | Salmon, R.M, Guo, J, Yu, M, Li, W. | 登録日 | 2019-07-30 | 公開日 | 2020-04-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Molecular basis of ALK1-mediated signalling by BMP9/BMP10 and their prodomain-bound forms. Nat Commun, 11, 2020
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6SCE
| Structure of a Type III CRISPR defence DNA nuclease activated by cyclic oligoadenylate | 分子名称: | Uncharacterized protein, cyclic oligoadenylate | 著者 | McMahon, S.A, Zhu, W, Graham, S, White, M.F, Gloster, T.M. | 登録日 | 2019-07-24 | 公開日 | 2020-02-19 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Structure and mechanism of a Type III CRISPR defence DNA nuclease activated by cyclic oligoadenylate. Nat Commun, 11, 2020
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4OVO
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6RDB
| CryoEM structure of Polytomella F-ATP synthase, Primary rotary state 1, focussed refinement of F1 head and rotor | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ... | 著者 | Murphy, B.J, Klusch, N, Yildiz, O, Kuhlbrandt, W. | 登録日 | 2019-04-12 | 公開日 | 2019-07-03 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F 1 -F o coupling. Science, 364, 2019
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6RDP
| Cryo-EM structure of Polytomella F-ATP synthase, Rotary substate 1C, focussed refinement of F1 head and rotor | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ... | 著者 | Murphy, B.J, Klusch, N, Yildiz, O, Kuhlbrandt, W. | 登録日 | 2019-04-12 | 公開日 | 2019-07-03 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F 1 -F o coupling. Science, 364, 2019
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6RDZ
| Cryo-EM structure of Polytomella F-ATP synthase, Rotary substate 2A, composite map | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ASA-10: Polytomella F-ATP synthase associated subunit 10, ... | 著者 | Murphy, B.J, Klusch, N, Yildiz, O, Kuhlbrandt, W. | 登録日 | 2019-04-12 | 公開日 | 2019-07-03 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F 1 -F o coupling. Science, 364, 2019
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6REF
| Cryo-EM structure of Polytomella F-ATP synthase, Rotary substate 3B, monomer-masked refinement | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ASA-10: Polytomella F-ATP synthase associated subunit 10, ... | 著者 | Murphy, B.J, Klusch, N, Yildiz, O, Kuhlbrandt, W. | 登録日 | 2019-04-12 | 公開日 | 2019-07-03 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F 1 -F o coupling. Science, 364, 2019
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6RDL
| Cryo-EM structure of Polytomella F-ATP synthase, Rotary substate 1B, monomer-masked refinement | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ASA-10: Polytomella F-ATP synthase associated subunit 10, ... | 著者 | Murphy, B.J, Klusch, N, Yildiz, O, Kuhlbrandt, W. | 登録日 | 2019-04-12 | 公開日 | 2019-07-03 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F 1 -F o coupling. Science, 364, 2019
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6RE1
| Cryo-EM structure of Polytomella F-ATP synthase, Rotary substate 2A, focussed refinement of F1 head and rotor | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ... | 著者 | Murphy, B.J, Klusch, N, Yildiz, O, Kuhlbrandt, W. | 登録日 | 2019-04-12 | 公開日 | 2019-07-03 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F 1 -F o coupling. Science, 364, 2019
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