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PDB: 12479 件

1T48
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Allosteric Inhibition of Protein Tyrosine Phosphatase 1B
分子名称: 3-(3,5-DIBROMO-4-HYDROXY-BENZOYL)-2-ETHYL-BENZOFURAN-6-SULFONIC ACID DIMETHYLAMIDE, Protein-tyrosine phosphatase, non-receptor type 1
著者Wiesmann, C, Barr, K.J, Kung, J, Zhu, J, Shen, W, Fahr, B.J, Zhong, M, Erlanson, D.A, Taylor, L, Randal, M, McDowell, R.S, Hansen, S.K.
登録日2004-04-28
公開日2004-07-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Allosteric inhibition of protein tyrosine phosphatase 1B
Nat.Struct.Mol.Biol., 11, 2004
2OW0
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MMP-9 active site mutant with iodine-labeled carboxylate inhibitor
分子名称: CALCIUM ION, CHLORIDE ION, Matrix metalloproteinase-9 (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB), ...
著者Tochowicz, A, Bode, W, Maskos, K, Goettig, P.
登録日2007-02-15
公開日2007-06-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structures of MMP-9 Complexes with Five Inhibitors: Contribution of the Flexible Arg424 Side-chain to Selectivity.
J.Mol.Biol., 371, 2007
1T3H
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X-ray Structure of Dephospho-CoA Kinase from E. coli Norteast Structural Genomics Consortium Target ER57
分子名称: Dephospho-CoA kinase, SULFATE ION
著者Kuzin, A.P, Chen, Y, Forouhar, F, Edstrom, W, Benach, J, Vorobiev, S, Acton, T, Shastry, R, Ma, L.-C, Xia, R, Montelione, G, Tong, L, Hunt, J, Northeast Structural Genomics Consortium (NESG)
登録日2004-04-26
公開日2004-05-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献X-ray Structure of Dephospho-CoA Kinase from E. coli Norteast Structural Genomics Consortium Target ER57
TO BE PUBLISHED
2OL2
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High Resolution Structure of Native PCI in Space Group P21
分子名称: GLYCEROL, Plasma serine protease inhibitor
著者Li, W, Huntington, J.A.
登録日2007-01-18
公開日2007-03-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of native protein C inhibitor provides insight into its multiple functions.
J.Biol.Chem., 282, 2007
4PMN
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Crystal structure of the Mycobacterium tuberculosis Tat-secreted protein Rv2525c in complex with MES (monoclinic crystal form I)
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, SULFATE ION, ...
著者Bellinzoni, M, Haouz, A, Shepard, W, Alzari, P.M.
登録日2014-05-22
公開日2014-10-08
最終更新日2014-12-10
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Structural studies suggest a peptidoglycan hydrolase function for the Mycobacterium tuberculosis Tat-secreted protein Rv2525c.
J.Struct.Biol., 188, 2014
2O8N
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Crystal Structure of Mouse Apolipoprotein A-I Binding Protein
分子名称: ApoA-I binding protein, CHLORIDE ION, SULFATE ION
著者Shumilin, I.A, Jha, K.N, Zheng, H, Chruszcz, M, Cymborowski, M, Herr, J.C, Minor, W.
登録日2006-12-12
公開日2007-12-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Biochemical and Structural Characterization of Apolipoprotein A-I Binding Protein, a Novel Phosphoprotein with a Potential Role in Sperm Capacitation.
Endocrinology, 149, 2008
1T9K
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X-ray crystal structure of aIF-2B alpha subunit-related translation initiation factor [Thermotoga maritima]
分子名称: CHLORIDE ION, Probable methylthioribose-1-phosphate isomerase, SULFATE ION
著者Osipiuk, J, Skarina, T, Savchenko, A, Edwards, A, Cymborowski, M, Minor, W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2004-05-17
公開日2004-06-08
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献X-ray crystal structure of aIF-2B translation initiation factor from Thermotoga maritima
To be Published
4P69
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Acek (D477A) ICDH complex
分子名称: ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, Isocitrate dehydrogenase [NADP], ...
著者Jimin, Z, Nan, W, Shu, W, Zongchao, J.
登録日2014-03-22
公開日2014-10-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献The phosphatase mechanism of bifunctional kinase/phosphatase AceK.
Chem. Commun. (Camb.), 50, 2014
1TB6
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2.5A Crystal Structure of the Antithrombin-Thrombin-Heparin Ternary Complex
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-2,3,6-tri-O-sulfonato-beta-D-glucopyranose-(1-4)-2,3-di-O-methyl-6-O-sulfonato-alpha-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-beta-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-alpha-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-beta-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-alpha-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-beta-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-alpha-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-beta-D-glucopyranose-(1-4)-2,3-di-O-methyl-6-O-sulfonato-alpha-D-glucopyranose-(1-4)-2,3-di-O-methyl-beta-D-glucopyranuronic acid-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-2,3-di-O-methyl-alpha-L-idopyranuronic acid-(1-4)-methyl 3-O-methyl-2,6-di-O-sulfo-alpha-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Li, W, Johnson, D.J, Esmon, C.T, Huntington, J.A.
登録日2004-05-19
公開日2004-08-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the antithrombin-thrombin-heparin ternary complex reveals the antithrombotic mechanism of heparin.
Nat.Struct.Mol.Biol., 11, 2004
1T92
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Crystal structure of N-terminal truncated pseudopilin PulG
分子名称: General secretion pathway protein G, ZINC ION
著者Koehler, R, Schaefer, K, Mueller, S, Vignon, G, Diederichs, K, Philippsen, A, Ringler, P, Pugsley, A.P, Engel, A, Welte, W.
登録日2004-05-14
公開日2004-10-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure and assembly of the pseudopilin PulG.
Mol.Microbiol., 54, 2004
3NBI
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Crystal structure of human RMI1 N-terminus
分子名称: RecQ-mediated genome instability protein 1
著者Wang, F, Yang, Y, Singh, T.R, Busygina, V, Guo, R, Wan, K, Wang, W, Sung, P, Meetei, A.R, Lei, M.
登録日2010-06-03
公開日2010-09-22
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structures of RMI1 and RMI2, Two OB-Fold Regulatory Subunits of the BLM Complex.
Structure, 18, 2010
4RI2
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Crystal structure of the photoprotective protein PsbS from spinach
分子名称: CHLOROPHYLL A, MERCURY (II) ION, Photosystem II 22 kDa protein, ...
著者Fan, M, Li, M, Chang, W.
登録日2014-10-05
公開日2015-08-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structures of the PsbS protein essential for photoprotection in plants.
Nat.Struct.Mol.Biol., 22, 2015
2NU1
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Molecular structures of the complexes of SGPB with OMTKY3 aromatic P1 variants Trp18I, His18I, Phe18I and Tyr18I
分子名称: Ovomucoid, Streptogrisin B
著者Bateman, K.S, Anderson, S, Lu, W, Qasim, M.A, Huang, K, Laskowski Jr, M, James, M.N.G.
登録日2006-11-08
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular structures of the complexes of SGPB with OMTKY3 aromatic P1 variants Trp18I, His18I, Phe18I and Tyr18I
To be Published
4RI3
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Crystal structure of DCCD-modified PsbS from spinach
分子名称: DICYCLOHEXYLUREA, MERCURY (II) ION, Photosystem II 22 kDa protein, ...
著者Fan, M, Li, M, Chang, W.
登録日2014-10-05
公開日2015-08-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structures of the PsbS protein essential for photoprotection in plants.
Nat.Struct.Mol.Biol., 22, 2015
2OIG
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Crystal structure of RS21-C6 core segment and dm5CTP complex
分子名称: 2'-DEOXY-5-METHYLCYTIDINE 5'-(TETRAHYDROGEN TRIPHOSPHATE), RS21-C6
著者Wu, B, Liu, Y, Zhao, Q, Liao, S, Zhang, J, Bartlam, M, Chen, W, Rao, Z.
登録日2007-01-11
公開日2007-03-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal Structure of RS21-C6, Involved in Nucleoside Triphosphate Pyrophosphohydrolysis
J.Mol.Biol., 367, 2007
5UBB
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Crystal structure of human alpha N-terminal protein methyltransferase 1B
分子名称: Alpha N-terminal protein methyltransferase 1B, S-ADENOSYLMETHIONINE, UNKNOWN ATOM OR ION
著者Dong, C, Zhu, L, Tempel, W, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2016-12-20
公開日2017-03-22
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献An asparagine/glycine switch governs product specificity of human N-terminal methyltransferase NTMT2.
Commun Biol, 1, 2018
5UBI
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Catalytic core domain of Adenosine triphosphate phosphoribosyltransferase from Campylobacter jejuni with bound PRPP
分子名称: 1,2-ETHANEDIOL, 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, ACETATE ION, ...
著者Mittelstaedt, G, Jiao, W, Livingstone, E.K, Parker, E.J.
登録日2016-12-20
公開日2017-12-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献A dimeric catalytic core relates the short and long forms of ATP-phosphoribosyltransferase.
Biochem. J., 475, 2018
3NI7
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Crystal structure of the TetR transcriptional regulator from Nitrosomonas europaea ATCC 19718
分子名称: Bacterial regulatory proteins, TetR family
著者Knapik, A, Chruszcz, M, Cymborowski, M, Xu, X, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2010-06-15
公開日2010-08-11
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Crystal structure of the TetR transcriptional regulator from Nitrosomonas europaea ATCC 19718
To be Published
5UBA
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Human RNA Pseudouridylate Synthase Domain Containing 4
分子名称: CALCIUM ION, CHLORIDE ION, RNA pseudouridylate synthase domain-containing protein 4, ...
著者DONG, A, ZENG, H, TEMPEL, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, BROWN, P.J, WU, H, Structural Genomics Consortium (SGC)
登録日2016-12-20
公開日2017-02-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献The Crystal Structure of Human Pseudouridylate Synthase Domain Containing 4. To be published
to be published
5UBH
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Catalytic core domain of Adenosine triphosphate phosphoribosyltransferase from Campylobacter jejuni with bound ATP
分子名称: ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, ATP phosphoribosyltransferase, ...
著者Mittelstaedt, G, Jiao, W, Livingstone, E.K, Parker, E.J.
登録日2016-12-20
公開日2017-12-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A dimeric catalytic core relates the short and long forms of ATP-phosphoribosyltransferase.
Biochem. J., 475, 2018
4ROJ
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Crystal Structure of the VAV2 SH2 domain in complex with TXNIP phosphorylated peptide
分子名称: Guanine nucleotide exchange factor VAV2, Thioredoxin-interacting protein, UNKNOWN ATOM OR ION
著者Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2014-10-28
公開日2014-12-10
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structure of the VAV2 SH2 domain in complex with TXNIP phosphorylated peptide
TO BE PUBLISHED
3NKV
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Crystal structure of Rab1b covalently modified with AMP at Y77
分子名称: ADENOSINE MONOPHOSPHATE, BARIUM ION, MAGNESIUM ION, ...
著者Mueller, M.P, Peters, H, Blankenfeldt, W, Goody, R.S, Itzen, A.
登録日2010-06-21
公開日2010-08-04
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Legionella effector protein DrrA AMPylates the membrane traffic regulator Rab1b.
Science, 329, 2010
1T1E
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High Resolution Crystal Structure of the Intact Pro-Kumamolisin, a Sedolisin Type Proteinase (previously called Kumamolysin or KSCP)
分子名称: CALCIUM ION, kumamolisin
著者Comellas-Bigler, M, Maskos, K, Huber, R, Oyama, H, Oda, K, Bode, W.
登録日2004-04-16
公開日2004-08-03
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.18 Å)
主引用文献1.2 a crystal structure of the serine carboxyl proteinase pro-kumamolisin: structure of an intact pro-subtilase
Structure, 12, 2004
4RQF
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human Seryl-tRNA synthetase dimer complexed with one molecule of tRNAsec
分子名称: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SERINE, Serine--tRNA ligase, ...
著者Xie, W, Wang, C, Guo, Y, Tian, Q, Jia, Q.
登録日2014-11-03
公開日2015-11-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.503 Å)
主引用文献SerRS-tRNASec complex structures reveal mechanism of the first step in selenocysteine biosynthesis.
Nucleic Acids Res., 43, 2015
4RLM
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Hen egg-white lysozyme solved from serial crystallography at a synchrotron source, data processed with CrystFEL
分子名称: Lysozyme C
著者Botha, S, Nass, K, Barends, T, Kabsch, W, Latz, B, Dworkowski, F, Foucar, L, Panepucci, E, Wang, M, Shoeman, R, Schlichting, I, Doak, R.B.
登録日2014-10-17
公開日2015-02-25
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Room-temperature serial crystallography at synchrotron X-ray sources using slowly flowing free-standing high-viscosity microstreams.
Acta Crystallogr.,Sect.D, 71, 2015

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