6UET
| SAM-bound SAM-IV riboswitch | 分子名称: | RNA (119-MER), S-ADENOSYLMETHIONINE | 著者 | Zhang, K, Li, S, Kappel, K, Pintilie, G, Su, Z, Mou, T, Schmid, M, Das, R, Chiu, W. | 登録日 | 2019-09-23 | 公開日 | 2019-12-18 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Cryo-EM structure of a 40 kDa SAM-IV riboswitch RNA at 3.7 angstrom resolution. Nat Commun, 10, 2019
|
|
6ZPD
| gamma-tocopherol transfer protein | 分子名称: | (2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alpha-tocopherol transfer protein, ... | 著者 | Aeschimann, W, Kammer, S, Staats, S, Stocker, A. | 登録日 | 2020-07-08 | 公開日 | 2020-12-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Engineering of a functional gamma-tocopherol transfer protein. Redox Biol, 38, 2020
|
|
6ZQJ
| Cryo-EM structure of trimeric prME spike of Spondweni virus | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein, prM | 著者 | Renner, M, Dejnirattisai, W, Carrique, L, Serna Martin, I, Karia, D, Ilca, S.L, Ho, S.F, Kotecha, A, Keown, J.R, Mongkolsapaya, J, Screaton, G.R, Grimes, J.M. | 登録日 | 2020-07-09 | 公開日 | 2021-01-20 | 最終更新日 | 2021-08-04 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins. Nat Commun, 12, 2021
|
|
6ZQV
| Cryo-EM structure of mature Spondweni virus | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein | 著者 | Renner, M, Dejnirattisai, W, Carrique, L, Serna Martin, I, Karia, D, Ilca, S.L, Ho, S.F, Kotecha, A, Keown, J.R, Mongkolsapaya, J, Screaton, G.R, Grimes, J.M. | 登録日 | 2020-07-10 | 公開日 | 2021-01-20 | 最終更新日 | 2021-08-04 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins. Nat Commun, 12, 2021
|
|
6UBY
| Isolated cofilin bound to an actin filament | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Huehn, A.R, Bibeau, J.P, Schramm, A.C, Cao, W, De La Cruz, E.M, Sindelar, C.V. | 登録日 | 2019-09-13 | 公開日 | 2020-01-01 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (7.5 Å) | 主引用文献 | Structures of cofilin-induced structural changes reveal local and asymmetric perturbations of actin filaments. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6UES
| Apo SAM-IV Riboswitch | 分子名称: | RNA (119-MER) | 著者 | Zhang, K, Li, S, Kappel, K, Pintilie, G, Su, Z, Mou, T, Schmid, M, Das, R, Chiu, W. | 登録日 | 2019-09-23 | 公開日 | 2019-12-18 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-EM structure of a 40 kDa SAM-IV riboswitch RNA at 3.7 angstrom resolution. Nat Commun, 10, 2019
|
|
6UJF
| Crystal structure of the Clostridial cellulose synthase subunit Z (CcsZ) from Clostridioides difficile | 分子名称: | Endoglucanase, beta-D-glucopyranose | 著者 | Scott, W, Lowrance, B, Anderson, A.C, Weadge, J.T. | 登録日 | 2019-10-03 | 公開日 | 2020-10-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Identification of the Clostridial cellulose synthase and characterization of the cognate glycosyl hydrolase, CcsZ. Plos One, 15, 2020
|
|
6ZQW
| Cryo-EM structure of immature Spondweni virus | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein, prM | 著者 | Renner, M, Dejnirattisai, W, Carrique, L, Serna Martin, I, Karia, D, Ilca, S.L, Ho, S.F, Kotecha, A, Keown, J.R, Mongkolsapaya, J, Screaton, G.R, Grimes, J.M. | 登録日 | 2020-07-10 | 公開日 | 2021-01-20 | 最終更新日 | 2021-08-04 | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | 主引用文献 | Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins. Nat Commun, 12, 2021
|
|
6ZU4
| Human Sirt6 13-308 in complex with ADP-ribose and the activator fluvastatin | 分子名称: | (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid, GLYCEROL, NAD-dependent protein deacetylase sirtuin-6, ... | 著者 | You, W, Steegborn, C. | 登録日 | 2020-07-21 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Structural Basis for Activation of Human Sirtuin 6 by Fluvastatin. Acs Med.Chem.Lett., 11, 2020
|
|
7B7O
| Solution structure of A. thaliana core TatA in DHPC micelles | 分子名称: | Sec-independent protein translocase protein TATA, chloroplastic | 著者 | Pettersson, P, Ye, W, Jakob, M, Tannert, F, Klosgen, R.B, Maler, L. | 登録日 | 2020-12-11 | 公開日 | 2021-01-13 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and dynamics of plant TatA in micelles and lipid bilayers studied by solution NMR. FEBS J, 285, 2018
|
|
6VQW
| Type I-F CRISPR-Csy complex with its inhibitor AcrF8 | 分子名称: | AcrF8, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, ... | 著者 | Zhang, K, Li, S, Pintilie, G, Zhu, Y, Huang, Z, Chiu, W. | 登録日 | 2020-02-06 | 公開日 | 2020-03-11 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | 主引用文献 | Inhibition mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F CRISPR-Cas complex revealed by cryo-EM. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
7BVV
| Crystal structure of sulfonic peroxiredoxin Ahp1 in complex with thioredoxin Trx2 | 分子名称: | Peroxiredoxin AHP1, Thioredoxin-2 | 著者 | Lian, F.M, Jiang, Y.L, Yang, W, Yang, X. | 登録日 | 2020-04-11 | 公開日 | 2020-07-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Crystal structure of sulfonic peroxiredoxin Ahp1 in complex with thioredoxin Trx2 mimics a conformational intermediate during the catalytic cycle. Int.J.Biol.Macromol., 161, 2020
|
|
6VZX
| Structure of a Covalently Captured Collagen Triple Helix using Lysine-Glutamate Pairs | 分子名称: | collagen mimetic peptide | 著者 | Miller, M.D, Hulgan, S.A, Xu, W, Kosgei, A.J, Phillips Jr, G.N, Hartgerink, J.D. | 登録日 | 2020-02-28 | 公開日 | 2020-09-02 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Covalent Capture of Collagen Triple Helices Using Lysine-Aspartate and Lysine-Glutamate Pairs. Biomacromolecules, 21, 2020
|
|
6W52
| Prefusion RSV F bound by neutralizing antibody RSB1 | 分子名称: | Fusion glycoprotein F0, Fusion glycoprotein F1 fused with Fibritin trimerization domain, RSB1 Fab Heavy Chain, ... | 著者 | Harshbarger, W, Chandramouli, S, Malito, M. | 登録日 | 2020-03-12 | 公開日 | 2020-11-11 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.74 Å) | 主引用文献 | Convergent structural features of respiratory syncytial virus neutralizing antibodies and plasticity of the site V epitope on prefusion F. Plos Pathog., 16, 2020
|
|
7AAY
| Crystal structure of MerTK kinase domain in complex with Merestinib | 分子名称: | CHLORIDE ION, N-(3-fluoro-4-{[1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxy}phenyl)-1-(4-fluorophenyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide, Tyrosine-protein kinase Mer | 著者 | Schimpl, M, Pflug, A, McCoull, W, Nissink, J.W.M, Overman, R.C, Rawlins, P.B, Truman, C, Underwood, E, Warwicker, J, Winter-Holt, J. | 登録日 | 2020-09-05 | 公開日 | 2020-10-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | A-loop interactions in Mer tyrosine kinase give rise to inhibitors with two-step mechanism and long residence time of binding. Biochem.J., 477, 2020
|
|
7AB2
| Crystal structure of MerTK kinase domain in complex with UNC2025 | 分子名称: | 4-[2-(butylamino)-5-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexan-1-ol, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Pflug, A, Schimpl, M, McCoull, W, Nissink, J.W.M, Overman, R.C, Rawlins, P.B, Truman, C, Underwood, E, Warwicker, J, Winter-Holt, J. | 登録日 | 2020-09-05 | 公開日 | 2020-10-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | A-loop interactions in Mer tyrosine kinase give rise to inhibitors with two-step mechanism and long residence time of binding. Biochem.J., 477, 2020
|
|
6ZQI
| Cryo-EM structure of Spondweni virus prME | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein | 著者 | Renner, M, Dejnirattisai, W, Carrique, L, Serna Martin, I, Karia, D, Ilca, S.L, Ho, S.F, Kotecha, A, Keown, J.R, Mongkolsapaya, J, Screaton, G.R, Grimes, J.M. | 登録日 | 2020-07-09 | 公開日 | 2021-01-20 | 最終更新日 | 2021-08-04 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins. Nat Commun, 12, 2021
|
|
7AB1
| Crystal structure of MerTK kinase domain in complex with Gilteritinib | 分子名称: | 6-ethyl-3-[[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amino]-5-(oxan-4-ylamino)pyrazine-2-carboxamide, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Pflug, A, Schimpl, M, McCoull, W, Nissink, J.W.M, Overman, R.C, Rawlins, P.B, Truman, C, Underwood, E, Warwicker, J, Winter-Holt, J. | 登録日 | 2020-09-05 | 公開日 | 2020-10-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | A-loop interactions in Mer tyrosine kinase give rise to inhibitors with two-step mechanism and long residence time of binding. Biochem.J., 477, 2020
|
|
7A17
| Crystal structure of the 5-phosphatase domain of Synaptojanin1 bound to its substrate diC8-PI(3,4,5)P3 in complex with a nanobody | 分子名称: | (2R)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonooxy)cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}propane -1,2-diyl dioctanoate, GLYCEROL, Isoform 2 of Synaptojanin-1, ... | 著者 | Paesmans, J, Galicia, C, Martin, E, Versees, W. | 登録日 | 2020-08-12 | 公開日 | 2020-12-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | A structure of substrate-bound Synaptojanin1 provides new insights in its mechanism and the effect of disease mutations. Elife, 9, 2020
|
|
7C0N
| Crystal structure of a self-assembling galactosylated peptide homodimer | 分子名称: | SULFATE ION, Self-assembling galactosylated tyrosine-rich peptide, beta-D-galactopyranose | 著者 | He, C, Wu, S, Chi, C, Zhang, W, Ma, M, Lai, L, Dong, S. | 登録日 | 2020-05-01 | 公開日 | 2020-10-07 | 最終更新日 | 2020-10-21 | 実験手法 | X-RAY DIFFRACTION (1.552 Å) | 主引用文献 | Glycopeptide Self-Assembly Modulated by Glycan Stereochemistry through Glycan-Aromatic Interactions. J.Am.Chem.Soc., 142, 2020
|
|
7BQW
| |
6UJU
| Structure of the HIV-1 gp41 transmembrane domain and cytoplasmic tail (LLP2) | 分子名称: | Envelope glycoprotein GP41 | 著者 | Piai, A, Fu, Q, Cai, Y, Ghantous, F, Xiao, T, Shaik, M.M, Peng, H, Rits-Volloch, S, Liu, Z, Chen, W, Seaman, M.S, Chen, B, Chou, J.J. | 登録日 | 2019-10-03 | 公開日 | 2020-05-13 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis of transmembrane coupling of the HIV-1 envelope glycoprotein. Nat Commun, 11, 2020
|
|
1Z3T
| |
6WBK
| |
6VJV
| Crystal structure of the Prochlorococcus phage (myovirus P-SSM2) ferredoxin at 1.6 Angstroms | 分子名称: | ACETATE ION, FE2/S2 (INORGANIC) CLUSTER, Ferredoxin, ... | 著者 | Olmos Jr, J.L, Campbell, I.J, Miller, M.D, Xu, W, Kahanda, D, Atkinson, J.T, Sparks, N, Bennett, G.N, Silberg, J.J, Phillips Jr, G.N. | 登録日 | 2020-01-17 | 公開日 | 2020-02-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Prochlorococcusphage ferredoxin: structural characterization and electron transfer to cyanobacterial sulfite reductases. J.Biol.Chem., 295, 2020
|
|