7JMB
 
 | | Crystal structure of Nitrogenase iron-molybdenum cofactor biosynthesis enzyme NifB from Methanothermobacter thermautotrophicus with three Fe4S4 clusters | | Descriptor: | IRON/SULFUR CLUSTER, Nitrogenase iron-molybdenum cofactor biosynthesis protein NifB | | Authors: | Kang, W, Rettberg, L, Ribbe, M.W, Hu, Y. | | Deposit date: | 2020-07-31 | | Release date: | 2020-10-28 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | X-Ray Crystallographic Analysis of NifB with a Full Complement of Clusters: Structural Insights into the Radical SAM-Dependent Carbide Insertion During Nitrogenase Cofactor Assembly.
Angew.Chem.Int.Ed.Engl., 60, 2021
|
|
1FPD
 | | STRUCTURAL ASPECTS OF THE ALLOSTERIC INHIBITION OF FRUCTOSE-1,6-BISPHOSPHATASE BY AMP: THE BINDING OF BOTH THE SUBSTRATE ANALOGUE 2,5-ANHYDRO-D-GLUCITOL-1,6-BISPHOSPHATE AND CATALYTIC METAL IONS MONITORED BY X-RAY CRYSTALLOGRAPHY | | Descriptor: | 2,5-anhydro-1,6-di-O-phosphono-D-glucitol, ADENOSINE MONOPHOSPHATE, FRUCTOSE 1,6-BISPHOSPHATASE, ... | | Authors: | Villeret, V, Huang, S, Zhang, Y, Lipscomb, W.N. | | Deposit date: | 1994-12-15 | | Release date: | 1995-02-27 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural aspects of the allosteric inhibition of fructose-1,6-bisphosphatase by AMP: the binding of both the substrate analogue 2,5-anhydro-D-glucitol 1,6-bisphosphate and catalytic metal ions monitored by X-ray crystallography.
Biochemistry, 34, 1995
|
|
7QWA
 | |
3CNN
 | | GTP-bound structure of TM YlqF | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Putative uncharacterized protein | | Authors: | Kim, D.J, Jang, J.Y, Yoon, H.-J, Suh, S.W. | | Deposit date: | 2008-03-26 | | Release date: | 2008-06-24 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of YlqF, a circularly permuted GTPase: Implications for its GTPase activation in 50 S ribosomal subunit assembly
Proteins, 72, 2008
|
|
1FJG
 | | STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH THE ANTIBIOTICS STREPTOMYCIN, SPECTINOMYCIN, AND PAROMOMYCIN | | Descriptor: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | | Authors: | Carter, A.P, Clemons Jr, W.M, Brodersen, D.E, Wimberly, B.T, Morgan-Warren, R.J, Ramakrishnan, V. | | Deposit date: | 2000-08-08 | | Release date: | 2000-09-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics
Nature, 407, 2000
|
|
8G5B
 | |
8G6G
 | |
8G6Q
 | |
8G6S
 | |
8G5A
 | |
6HLR
 | | Yeast RNA polymerase I elongation complex bound to nucleotide analog GMPCPP (core focused) | | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | Authors: | Tafur, L, Sadian, Y, Weis, F, Muller, C.W. | | Deposit date: | 2018-09-11 | | Release date: | 2019-04-03 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.18 Å) | | Cite: | The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2.
Elife, 8, 2019
|
|
3CQP
 | | Human SOD1 G85R Variant, Structure I | | Descriptor: | COPPER (II) ION, MALONATE ION, Superoxide dismutase [Cu-Zn], ... | | Authors: | Cao, X, Antonyuk, S, Seetharaman, S.V, Whitson, L.J, Taylor, A.B, Holloway, S.P, Strange, R.W, Doucette, P.A, Valentine, J.S, Tiwari, A, Hayward, L.J, Padua, S, Cohlberg, J.A, Hasnain, S.S, Hart, P.J. | | Deposit date: | 2008-04-03 | | Release date: | 2008-04-29 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structures of the G85R Variant of SOD1 in Familial Amyotrophic Lateral Sclerosis.
J.Biol.Chem., 283, 2008
|
|
7X3A
 | | NMR solution structure of the 1:1 complex of a pyridostatin (PDS) bound to a G-quadruplex MYT1L | | Descriptor: | 4-(2-azanylethoxy)-N2,N6-bis[4-(2-azanylethoxy)quinolin-2-yl]pyridine-2,6-dicarboxamide, G-quadruplex DNA MYT1L | | Authors: | Liu, L.-Y, Mao, Z.-W, Liu, W. | | Deposit date: | 2022-02-28 | | Release date: | 2022-06-08 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural Basis of Pyridostatin and Its Derivatives Specifically Binding to G-Quadruplexes.
J.Am.Chem.Soc., 144, 2022
|
|
8T76
 | | SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 3 bp R-loop | | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | | Deposit date: | 2023-06-19 | | Release date: | 2024-05-01 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.42 Å) | | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
|
|
7QOF
 | | Icosahedral capsid of the phicrAss001 virion | | Descriptor: | Auxiliary capsid protein gp36, Head fiber dimer protein gp29, Head fiber trimer protein gp21, ... | | Authors: | Bayfield, O.W, Shkoporov, A.N, Yutin, N, Khokhlova, E.V, Smith, J.L.R, Hawkins, D.E.D.P, Koonin, E.V, Hill, C, Antson, A.A. | | Deposit date: | 2021-12-24 | | Release date: | 2023-03-29 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.01 Å) | | Cite: | Structural atlas of a human gut crassvirus.
Nature, 617, 2023
|
|
7QOG
 | | Portal protein assembly of the phicrAss001 virion with C12 symmetry imposed | | Descriptor: | Cargo protein 1 gp45, Portal protein gp20, Ring protein 1 gp43, ... | | Authors: | Bayfield, O.W, Shkoporov, A.N, Yutin, N, Khokhlova, E.V, Smith, J.L.R, Hawkins, D.E.D.P, Koonin, E.V, Hill, C, Antson, A.A. | | Deposit date: | 2021-12-24 | | Release date: | 2023-03-29 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.09 Å) | | Cite: | Structural atlas of a human gut crassvirus.
Nature, 617, 2023
|
|
4D4F
 | | Mutant P250A of bacterial chalcone isomerase from Eubacterium ramulus | | Descriptor: | CHALCONE ISOMERASE, CHLORIDE ION, GLYCEROL | | Authors: | Thomsen, M, Kratzat, H, Hinrichs, W. | | Deposit date: | 2014-10-28 | | Release date: | 2016-01-20 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.34 Å) | | Cite: | Structural Basis for (2 R ,3 R )-Taxifolin Binding and Reaction Products to the Bacterial Chalcone Isomerase of Eubacterium ramulus.
Molecules, 27, 2022
|
|
7QOK
 | | Tail muzzle assembly of the phicrAss001 virion with C6 symmetry imposed | | Descriptor: | MAGNESIUM ION, Muzzle bound helix, Muzzle protein gp44, ... | | Authors: | Bayfield, O.W, Shkoporov, A.N, Yutin, N, Khokhlova, E.V, Smith, J.L.R, Hawkins, D.E.D.P, Koonin, E.V, Hill, C, Antson, A.A. | | Deposit date: | 2021-12-24 | | Release date: | 2023-03-29 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.38 Å) | | Cite: | Structural atlas of a human gut crassvirus.
Nature, 617, 2023
|
|
7QOJ
 | | Tail barrel assembly of the phicrAss001 virion with C12 symmetry imposed | | Descriptor: | Cargo protein 1 gp45, MAGNESIUM ION, Portal protein gp20, ... | | Authors: | Bayfield, O.W, Shkoporov, A.N, Yutin, N, Khokhlova, E.V, Smith, J.L.R, Hawkins, D.E.D.P, Koonin, E.V, Hill, C, Antson, A.A. | | Deposit date: | 2021-12-24 | | Release date: | 2023-03-29 | | Last modified: | 2023-05-24 | | Method: | ELECTRON MICROSCOPY (3.21 Å) | | Cite: | Structural atlas of a human gut crassvirus.
Nature, 617, 2023
|
|
4H38
 | |
8GN6
 | | Crystallization of Sialidase from Porphyromonas gingivalis | | Descriptor: | Sialidase, UNKNOWN LIGAND | | Authors: | Dong, W.B. | | Deposit date: | 2022-08-23 | | Release date: | 2023-04-19 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural and enzymatic characterization of the sialidase SiaPG from Porphyromonas gingivalis.
Acta Crystallogr.,Sect.F, 79, 2023
|
|
4H4E
 | | IspH in complex with (E)-4-mercapto-3-methylbut-2-enyl diphosphate | | Descriptor: | (2E)-3-methyl-4-sulfanylbut-2-en-1-yl trihydrogen diphosphate, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, IRON/SULFUR CLUSTER | | Authors: | Span, I, Eisenreich, W, Jauch, J, Bacher, A, Groll, M. | | Deposit date: | 2012-09-17 | | Release date: | 2013-01-23 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structures of Fluoro, Amino, and Thiol Inhibitors Bound to the [Fe(4) S(4) ] Protein IspH.
Angew.Chem.Int.Ed.Engl., 52, 2013
|
|
7X8R
 | | Cryo-EM structure of the Boc5-bound hGLP-1R-Gs complex | | Descriptor: | 2,4-bis(3-methoxy-4-thiophen-2-ylcarbonyloxy-phenyl)-1,3-bis[[4-[(2-methylpropan-2-yl)oxycarbonylamino]phenyl]carbonylamino]cyclobutane-1,3-dicarboxylic acid, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Cong, Z.T, Zhou, Q.T, Li, Y, Chen, L.N, Zhang, Z.C, Liang, A.Y, Liu, Q, Wu, X.Y, Dai, A.T, Xia, T, Wu, W, Zhang, Y, Yang, D.H, Wang, M.W. | | Deposit date: | 2022-03-14 | | Release date: | 2022-06-29 | | Method: | ELECTRON MICROSCOPY (2.61 Å) | | Cite: | Structural basis of peptidomimetic agonism revealed by small- molecule GLP-1R agonists Boc5 and WB4-24.
Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
3JY9
 | | Janus Kinase 2 Inhibitors | | Descriptor: | (3S)-3-(4-hydroxyphenyl)-1,5-dihydro-1,5,12-triazabenzo[4,5]cycloocta[1,2,3-cd]inden-4(3H)-one, SODIUM ION, Tyrosine-protein kinase JAK2 | | Authors: | Zuccola, H.J, Ledeboer, M.W, Pierce, A.C. | | Deposit date: | 2009-09-21 | | Release date: | 2009-12-01 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Janus kinase 2 inhibitors. Synthesis and characterization of a novel polycyclic azaindole.
J.Med.Chem., 52, 2009
|
|
1FO7
 | | HUMAN PRION PROTEIN MUTANT E200K FRAGMENT 90-231 | | Descriptor: | PRION PROTEIN | | Authors: | Zhang, Y, Swietnicki, W, Zagorski, M.G, Surewicz, W.K, Soennichsen, F.D. | | Deposit date: | 2000-08-25 | | Release date: | 2000-09-21 | | Last modified: | 2018-03-14 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the E200K variant of human prion protein. Implications for the mechanism of pathogenesis in familial prion diseases.
J.Biol.Chem., 275, 2000
|
|
