6Q5P
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![BU of 6q5p by Molmil](/molmil-images/mine/6q5p) | Crystal structure of a CC-Hex mutant that forms a parallel six-helix coiled coil CC-Hex*-II | Descriptor: | CC-Hex*-II, GLYCEROL, PHOSPHATE ION | Authors: | Rhys, G.G, Wood, C.W, Beesley, J.L, Brady, R.L, Woolfson, D.N. | Deposit date: | 2018-12-09 | Release date: | 2019-05-22 | Last modified: | 2019-06-19 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Navigating the Structural Landscape of De Novo alpha-Helical Bundles. J.Am.Chem.Soc., 141, 2019
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4GSU
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![BU of 4gsu by Molmil](/molmil-images/mine/4gsu) | Structural basis for the inhibition of Mycobacterium tuberculosis L,D-transpeptidase by meropenem, a drug effective against extensively drug-resistant strains | Descriptor: | (2S,3R,4S)-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, Probable conserved lipoprotein LPPS | Authors: | Kim, H.S, Kim, J, Im, H.N, Yoon, J.Y, An, D.R, Yoon, H.J, Kim, J.Y, Min, H.K, Kim, S.-J, Lee, J.Y, Han, B.W, Suh, S.W. | Deposit date: | 2012-08-28 | Release date: | 2013-02-27 | Last modified: | 2022-02-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for the inhibition of Mycobacterium tuberculosis L,D-transpeptidase by meropenem, a drug effective against extensively drug-resistant strains Acta Crystallogr.,Sect.D, 69, 2013
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6WDV
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5WHQ
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![BU of 5whq by Molmil](/molmil-images/mine/5whq) | Crystal structure of the catalase-peroxidase from Neurospora crassa at 2.9 A | Descriptor: | Catalase-peroxidase, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Diaz-Vilchis, A, Vega-Garcia, V, Rudino-Pinera, E, Hansberg, W. | Deposit date: | 2017-07-18 | Release date: | 2018-01-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure, kinetics, molecular and redox properties of a cytosolic and developmentally regulated fungal catalase-peroxidase. Arch. Biochem. Biophys., 640, 2018
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5WEI
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![BU of 5wei by Molmil](/molmil-images/mine/5wei) | Crystal structure of the influenza virus PA endonuclease (E119D mutant) in complex with inhibitor 7a (SRI-29770) | Descriptor: | 2-[(2S)-1-(2,6-dichlorobenzene-1-carbonyl)pyrrolidin-2-yl]-5-hydroxy-6-oxo-N-(2-phenylethyl)-1,6-dihydropyrimidine-4-carboxamide, MANGANESE (II) ION, Polymerase acidic protein, ... | Authors: | Kumar, G, White, S.W. | Deposit date: | 2017-07-10 | Release date: | 2017-12-27 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease. Sci Rep, 7, 2017
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1JQW
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![BU of 1jqw by Molmil](/molmil-images/mine/1jqw) | THE 2.3 ANGSTROM RESOLUTION STRUCTURE OF BACILLUS SUBTILIS LUXS/HOMOCYSTEINE COMPLEX | Descriptor: | 2-AMINO-4-MERCAPTO-BUTYRIC ACID, Autoinducer-2 production protein luxS, ZINC ION | Authors: | Ruzheinikov, S.N, Das, S.K, Sedelnikova, S.E, Hartley, A, Foster, S.J, Horsburgh, M.J, Cox, A.G, McCleod, C.W, Mekhalfia, A, Blackburn, G.M, Rice, D.W, Baker, P.J. | Deposit date: | 2001-08-09 | Release date: | 2001-10-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The 1.2 A structure of a novel quorum-sensing protein, Bacillus subtilis LuxS J.Mol.Biol., 313, 2001
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5WFP
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![BU of 5wfp by Molmil](/molmil-images/mine/5wfp) | Ligand-bound Ras:SOS:Ras complex | Descriptor: | 6-chloranyl-~{N}-(3-chloranyl-4-fluoranyl-phenyl)-1,2,3,4-tetrahydroacridin-9-amine, GTPase HRas, MAGNESIUM ION, ... | Authors: | Sun, Q, Phan, J, Burns, M.C, Fesik, S.W. | Deposit date: | 2017-07-12 | Release date: | 2018-05-23 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | High-throughput screening identifies small molecules that bind to the RAS:SOS:RAS complex and perturb RAS signaling. Anal. Biochem., 548, 2018
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4EHE
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![BU of 4ehe by Molmil](/molmil-images/mine/4ehe) | B-Raf Kinase Domain in Complex with an Aminothienopyrimidine-based Inhibitor | Descriptor: | 4-amino-N-{2,6-difluoro-3-[(propylsulfonyl)amino]phenyl}thieno[3,2-d]pyrimidine-7-carboxamide, Serine/threonine-protein kinase B-raf | Authors: | Voegtli, W.C. | Deposit date: | 2012-04-02 | Release date: | 2013-04-24 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Potent and selective aminopyrimidine-based B-raf inhibitors with favorable physicochemical and pharmacokinetic properties. J.Med.Chem., 55, 2012
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4RNJ
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![BU of 4rnj by Molmil](/molmil-images/mine/4rnj) | PaMorA phosphodiesterase domain, apo form | Descriptor: | Motility regulator | Authors: | Phippen, C.W, Tews, I. | Deposit date: | 2014-10-24 | Release date: | 2014-11-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Formation and dimerization of the phosphodiesterase active site of the Pseudomonas aeruginosa MorA, a bi-functional c-di-GMP regulator. Febs Lett., 588, 2014
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4GY4
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![BU of 4gy4 by Molmil](/molmil-images/mine/4gy4) | Role of the biradical intermediate observed during the turnover of SLAC: A two-domain laccase from Streptomyces coelicolor | Descriptor: | COPPER (II) ION, OXYGEN ATOM, Putative copper oxidase, ... | Authors: | Nederlof, I, Gupta, A, Canters, G.W. | Deposit date: | 2012-09-05 | Release date: | 2012-09-19 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | Involvement of Tyr108 in the enzyme mechanism of the small laccase from Streptomyces coelicolor J.Am.Chem.Soc., 134, 2012
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5JTH
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![BU of 5jth by Molmil](/molmil-images/mine/5jth) | Crystal structure of E67A calmodulin - CaM:RM20 analog complex | Descriptor: | CALCIUM ION, Calmodulin, Myosin light chain kinase, ... | Authors: | Grum-Tokars, V.L, Minasov, G, Anderson, W.F, Watterson, D.M. | Deposit date: | 2016-05-09 | Release date: | 2017-07-19 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Crystal structure of E67A calmodulin - CaM:RM20 analog complex To Be Published
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1G29
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![BU of 1g29 by Molmil](/molmil-images/mine/1g29) | MALK | Descriptor: | 1,4-DIETHYLENE DIOXIDE, AMMONIUM ION, CHLORIDE ION, ... | Authors: | Diederichs, K, Diez, J, Greller, G, Mueller, C, Breed, J, Schnell, C, Vonrhein, C, Boos, W, Welte, W. | Deposit date: | 2000-10-18 | Release date: | 2000-12-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of MalK, the ATPase subunit of the trehalose/maltose ABC transporter of the archaeon Thermococcus litoralis. EMBO J., 19, 2000
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3ARS
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![BU of 3ars by Molmil](/molmil-images/mine/3ars) | Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - apo structure of mutant W275G | Descriptor: | Chitinase A | Authors: | Pantoom, S, Vetter, I.R, Prinz, H, Suginta, W. | Deposit date: | 2010-12-09 | Release date: | 2011-04-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Potent family-18 chitinase inhibitors: x-ray structures, affinities, and binding mechanisms J.Biol.Chem., 286, 2011
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3ARO
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![BU of 3aro by Molmil](/molmil-images/mine/3aro) | Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - apo structure | Descriptor: | Chitinase A, GLYCEROL | Authors: | Pantoom, S, Vetter, I.R, Prinz, H, Suginta, W. | Deposit date: | 2010-12-09 | Release date: | 2011-04-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Potent family-18 chitinase inhibitors: x-ray structures, affinities, and binding mechanisms J.Biol.Chem., 286, 2011
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3ARY
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![BU of 3ary by Molmil](/molmil-images/mine/3ary) | Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with 2-(imidazolin-2-yl)-5-isothiocyanatobenzofuran | Descriptor: | 2-(5-isothiocyanato-1-benzofuran-2-yl)-4,5-dihydro-1H-imidazole, Chitinase A, GLYCEROL | Authors: | Pantoom, S, Vetter, I.R, Prinz, H, Suginta, W. | Deposit date: | 2010-12-09 | Release date: | 2011-04-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Potent family-18 chitinase inhibitors: x-ray structures, affinities, and binding mechanisms J.Biol.Chem., 286, 2011
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3ARU
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![BU of 3aru by Molmil](/molmil-images/mine/3aru) | Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - W275G mutant complex structure with PENTOXIFYLLINE | Descriptor: | 3,7-DIMETHYL-1-(5-OXOHEXYL)-3,7-DIHYDRO-1H-PURINE-2,6-DIONE, Chitinase A | Authors: | Pantoom, S, Vetter, I.R, Prinz, H, Suginta, W. | Deposit date: | 2010-12-09 | Release date: | 2011-04-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Potent family-18 chitinase inhibitors: x-ray structures, affinities, and binding mechanisms J.Biol.Chem., 286, 2011
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5JQA
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![BU of 5jqa by Molmil](/molmil-images/mine/5jqa) | CaM:RM20 complex | Descriptor: | CALCIUM ION, Calmodulin, Myosin light chain kinase, ... | Authors: | Tokars, V.L, Minasov, G, Anderson, W.F, Watterson, D.M. | Deposit date: | 2016-05-04 | Release date: | 2017-10-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | CaM:RM20 complex To be Published
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5WVC
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![BU of 5wvc by Molmil](/molmil-images/mine/5wvc) | Structure of the CARD-CARD disk | Descriptor: | Apoptotic protease-activating factor 1, Caspase, IODIDE ION | Authors: | Lin, S.C, Lo, Y.C, Su, T.W. | Deposit date: | 2016-12-24 | Release date: | 2017-04-19 | Method: | X-RAY DIFFRACTION (2.993 Å) | Cite: | Structural Insights into DD-Fold Assembly and Caspase-9 Activation by the Apaf-1 Apoptosome. Structure, 25, 2017
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3MZZ
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![BU of 3mzz by Molmil](/molmil-images/mine/3mzz) | Crystal Structure of Rhodanese-like Domain Protein from Staphylococcus aureus | Descriptor: | Rhodanese-like domain protein | Authors: | Kim, Y, Chruszcz, M, Minor, W, Edwards, A, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2010-05-13 | Release date: | 2010-06-30 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Rhodanese-like Domain Protein from Staphylococcus aureus To be Published
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3ART
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![BU of 3art by Molmil](/molmil-images/mine/3art) | Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - W275G mutant complex structure with DEQUALINIUM | Descriptor: | Chitinase A, DEQUALINIUM, GLYCEROL | Authors: | Pantoom, S, Vetter, I.R, Prinz, H, Suginta, W. | Deposit date: | 2010-12-09 | Release date: | 2011-04-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Potent family-18 chitinase inhibitors: x-ray structures, affinities, and binding mechanisms J.Biol.Chem., 286, 2011
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3ARX
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![BU of 3arx by Molmil](/molmil-images/mine/3arx) | Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with Propentofylline | Descriptor: | 3-methyl-1-(5-oxohexyl)-7-propyl-3,7-dihydro-1H-purine-2,6-dione, Chitinase A, GLYCEROL | Authors: | Pantoom, S, Vetter, I.R, Prinz, H, Suginta, W. | Deposit date: | 2010-12-09 | Release date: | 2011-04-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.16 Å) | Cite: | Potent family-18 chitinase inhibitors: x-ray structures, affinities, and binding mechanisms J.Biol.Chem., 286, 2011
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7X9R
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![BU of 7x9r by Molmil](/molmil-images/mine/7x9r) | Crystal structure of the antirepressor GmaR | Descriptor: | Glycosyl transferase family 2 | Authors: | Cho, S.Y, Na, H.W, Oh, H.B, Kwak, Y.M, Song, W.S, Park, S.C, Yoon, S.I. | Deposit date: | 2022-03-16 | Release date: | 2022-11-09 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural basis of flagellar motility regulation by the MogR repressor and the GmaR antirepressor in Listeria monocytogenes. Nucleic Acids Res., 50, 2022
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1KKO
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![BU of 1kko by Molmil](/molmil-images/mine/1kko) | CRYSTAL STRUCTURE OF CITROBACTER AMALONATICUS METHYLASPARTATE AMMONIA LYASE | Descriptor: | 3-METHYLASPARTATE AMMONIA-LYASE, SULFATE ION | Authors: | Levy, C.W, Buckley, P.A, Sedelnikova, S, Kato, Y, Asano, Y, Rice, D.W, Baker, P.J. | Deposit date: | 2001-12-10 | Release date: | 2002-01-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Insights into enzyme evolution revealed by the structure of methylaspartate ammonia lyase. Structure, 10, 2002
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6QJW
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![BU of 6qjw by Molmil](/molmil-images/mine/6qjw) | TetR(D) T103A mutant in complex with 7-chlortetracycline and magnesium | Descriptor: | 7-CHLOROTETRACYCLINE, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Hinrichs, W, Palm, G.J, Berndt, L, Girbardt, B. | Deposit date: | 2019-01-27 | Release date: | 2019-08-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding. Biochim Biophys Acta Proteins Proteom, 1868, 2020
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6F8A
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![BU of 6f8a by Molmil](/molmil-images/mine/6f8a) | |