3ARU
Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - W275G mutant complex structure with PENTOXIFYLLINE
Summary for 3ARU
Entry DOI | 10.2210/pdb3aru/pdb |
Related | 3ARO 3ARP 3ARQ 3ARR 3ARS 3ART 3ARV 3ARW 3ARX 3ARY 3ARZ 3AS0 3AS1 3AS2 3AS3 |
Descriptor | Chitinase A, 3,7-DIMETHYL-1-(5-OXOHEXYL)-3,7-DIHYDRO-1H-PURINE-2,6-DIONE (3 entities in total) |
Functional Keywords | tim barrel, inhibitor complex, glycosidase, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Vibrio harveyi |
Total number of polymer chains | 1 |
Total formula weight | 64547.54 |
Authors | Pantoom, S.,Vetter, I.R.,Prinz, H.,Suginta, W. (deposition date: 2010-12-09, release date: 2011-04-20, Last modification date: 2023-11-01) |
Primary citation | Pantoom, S.,Vetter, I.R.,Prinz, H.,Suginta, W. Potent family-18 chitinase inhibitors: x-ray structures, affinities, and binding mechanisms J.Biol.Chem., 286:24312-24323, 2011 Cited by PubMed: 21531720DOI: 10.1074/jbc.M110.183376 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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