6F8A

Crystal structure of cytochrome P450 CYP260A1 (S276I) bound with histidine

Summary for 6F8A

Entry DOI	10.2210/pdb6f8a/pdb
Descriptor	Cytochrome P450 CYP260A1, PROTOPORPHYRIN IX CONTAINING FE, HISTIDINE, ... (4 entities in total)
Functional Keywords	bacterial proteins, sorangium cellulosum, cytochrome p-450 enzyme system, cytochrome p450, hydroxylation, heme, oxidation-reduction, progesterone, histidine, biocatalysis, oxidoreductase
Biological source	Sorangium cellulosum (strain So ce56) (Polyangium cellulosum (strain So ce56))
Total number of polymer chains	2
Total formula weight	90593.25
Authors	Jozwik, I.K.,Thunnissen, A.M.W.H. (deposition date: 2017-12-12, release date: 2018-03-14, Last modification date: 2024-01-17)
Primary citation	Khatri, Y.,Jozwik, I.K.,Ringle, M.,Ionescu, I.A.,Litzenburger, M.,Hutter, M.C.,Thunnissen, A.W.H.,Bernhardt, R. Structure-Based Engineering of Steroidogenic CYP260A1 for Stereo- and Regioselective Hydroxylation of Progesterone. ACS Chem. Biol., 13:1021-1028, 2018 Cited by PubMed: 29509407 DOI: 10.1021/acschembio.8b00026 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.35 Å)

Structure validation