3ARX

Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with Propentofylline

Summary for 3ARX

Entry DOI	10.2210/pdb3arx/pdb
Related	3ARO 3ARP 3ARQ 3ARR 3ARS 3ART 3ARU 3ARV 3ARW 3ARY 3ARZ 3AS0 3AS1 3AS2 3AS3
Descriptor	Chitinase A, 3-methyl-1-(5-oxohexyl)-7-propyl-3,7-dihydro-1H-purine-2,6-dione, GLYCEROL, ... (4 entities in total)
Functional Keywords	tim barrel, inhibitor complex, glycosidase, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Vibrio harveyi
Total number of polymer chains	1
Total formula weight	64546.58
Authors	Pantoom, S.,Vetter, I.R.,Prinz, H.,Suginta, W. (deposition date: 2010-12-09, release date: 2011-04-20, Last modification date: 2023-11-01)
Primary citation	Pantoom, S.,Vetter, I.R.,Prinz, H.,Suginta, W. Potent family-18 chitinase inhibitors: x-ray structures, affinities, and binding mechanisms J.Biol.Chem., 286:24312-24323, 2011 Cited by PubMed: 21531720 DOI: 10.1074/jbc.M110.183376 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.16 Å)

Structure validation