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3ARX

Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with Propentofylline

Functional Information from GO Data
ChainGOidnamespacecontents
A0004553molecular_functionhydrolase activity, hydrolyzing O-glycosyl compounds
A0004568molecular_functionchitinase activity
A0005975biological_processcarbohydrate metabolic process
A0006032biological_processchitin catabolic process
A0008061molecular_functionchitin binding
Functional Information from PDB Data
site_idAC1
Number of Residues10
DetailsBINDING SITE FOR RESIDUE POY A 606
ChainResidue
ATRP275
AHOH1235
AGLY367
ALYS370
AASP392
ATRP397
ATYR435
AARG463
AHOH980
AHOH1113

site_idAC2
Number of Residues23
DetailsBINDING SITE FOR RESIDUE POY A 607
ChainResidue
ATRP168
AARG173
APHE192
AVAL205
AASN208
ASER209
AALA212
AHIS228
AASP229
ATHR276
ALEU277
AGLU498
AVAL501
AHOH803
AHOH832
AHOH845
AHOH949
AHOH1181
AHOH1213
AHOH1239
AHOH1276
AHOH1457
AHOH1595

site_idAC3
Number of Residues10
DetailsBINDING SITE FOR RESIDUE GOL A 3500
ChainResidue
AGLU114
ACYS121
ASER122
ALYS123
AGLY206
AGLY207
AASN211
AHOH696
AHOH880
AHOH961

Functional Information from PROSITE/UniProt
site_idPS01095
Number of Residues9
DetailsGH18_1 Glycosyl hydrolases family 18 (GH18) active site signature. YDGVDIDwE
ChainResidueDetails
ATYR307-GLU315

227344

PDB entries from 2024-11-13

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