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PDB: 34568 件

8SGA
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Crystal structure of 770E11, a monoclonal antibody isolated from a human Epstein-Barr virus seropositive donor
分子名称: 770E11 Fab heavy chain, 770E11 Fab light chain, GLYCEROL, ...
著者Chen, W.H, Jensen, J.L, Joyce, M.G.
登録日2023-04-12
公開日2024-04-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of 770E11, a monoclonal antibody isolated from a human Epstein-Barr virus seropositive donor
To Be Published
2ZX7
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alpha-L-fucosidase complexed with inhibitor, F10-2C
分子名称: Alpha-L-fucosidase, putative, N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}-1H-indole-2-carboxamide
著者Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J.
登録日2008-12-19
公開日2009-12-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
Angew.Chem.Int.Ed.Engl., 49, 2010
5B7C
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Crystal structure of octopus S-crystallin Q108F mutant in complex with glutathione
分子名称: GLUTATHIONE, S-crystallin OctvuS4, SULFATE ION
著者Chou, C.-Y, Tan, W.-H, Wu, C.-G.
登録日2016-06-07
公開日2016-08-03
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structure of a Highly Active Cephalopod S-crystallin Mutant: New Molecular Evidence for Evolution from an Active Enzyme into Lens-Refractive Protein.
Sci Rep, 6, 2016
8F7X
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Gi bound nociceptin receptor in complex with nociceptin peptide
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Wang, Y, Zhuang, Y, DiBerto, J.F, Zhou, X.E, Schmitz, G.P, Yuan, Q, Jain, M.K, Liu, W, Melcher, K, Jiang, Y, Roth, B.L, Xu, H.E.
登録日2022-11-20
公開日2022-12-14
最終更新日2023-02-01
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献Structures of the entire human opioid receptor family.
Cell, 186, 2023
4HN3
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The crystal structure of a sex pheromone precursor (lmo1757) from Listeria monocytogenes EGD-e
分子名称: BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Tan, K, Makowska-Grzyska, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2012-10-18
公開日2012-10-31
実験手法X-RAY DIFFRACTION (2.047 Å)
主引用文献The crystal structure of a sex pheromone precursor (lmo1757) from Listeria monocytogenes EGD-e
To be Published
3F4W
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BU of 3f4w by Molmil
The 1.65A Crystal Structure of 3-hexulose-6-phosphate synthase from Salmonella typhimurium
分子名称: MALONATE ION, Putative hexulose 6 phosphate synthase
著者Vijayalakshmi, J, Woodard, R.W.
登録日2008-11-03
公開日2008-11-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The 1.65A Crystal Structure of 3-hexulose-6-phosphate synthase from Salmonella typhimurium
To be Published
7PM4
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Cryo-EM structures of human fucosidase FucA1 reveal insight into substate recognition and catalysis.
分子名称: (2S,3R,4S,5R)-2-METHYLPIPERIDINE-3,4,5-TRIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Tissue alpha-L-fucosidase
著者Armstrong, Z, Meek, R.W, Wu, L, Blaza, J.N, Davies, G.J.
登録日2021-09-01
公開日2022-08-10
最終更新日2022-10-19
実験手法ELECTRON MICROSCOPY (2.49 Å)
主引用文献Cryo-EM structures of human fucosidase FucA1 reveal insight into substrate recognition and catalysis.
Structure, 30, 2022
1F0T
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BOVINE TRYPSIN COMPLEXED WITH RPR131247
分子名称: 4-HYDROXY-3-[2-OXO-3-(THIENO[3,2-B]PYRIDINE-2-SULFONYLAMINO)-PYRROLIDIN-1-YLMETHYL]-BENZAMIDINE, CALCIUM ION, SULFATE ION, ...
著者Maignan, S, Guilloteau, J.P, Pouzieux, S, Choi-Sledeski, Y.M, Becker, M.R, Klein, S.I, Ewing, W.R, Pauls, H.W, Spada, A.P, Mikol, V.
登録日2000-05-17
公開日2000-09-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of human factor Xa complexed with potent inhibitors.
J.Med.Chem., 43, 2000
1ND1
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Amino acid sequence and crystal structure of BaP1, a metalloproteinase from Bothrops asper snake venom that exerts multiple tissue-damaging activities.
分子名称: BaP1, ZINC ION
著者Watanabe, L, Shannon, J.D, Valente, R.H, Rucavado, A, Alape-Giron, A, Kamiguti, A.S, Theakston, R.D, Fox, J.W, Gutierrez, J.M, Arni, R.K.
登録日2002-12-06
公開日2003-11-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Amino acid sequence and crystal structure of BaP1, a metalloproteinase from Bothrops asper snake venom that exerts multiple tissue-damaging activities
Protein Sci., 12, 2003
8SFW
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Crystal structure of TuUGT202A2 (Tetur22g00270) in complex with quercetin
分子名称: 3,5,7,3',4'-PENTAHYDROXYFLAVONE, UDP-glycosyltransferase 202A2, URIDINE-5'-DIPHOSPHATE
著者Arriaza, R.H, Dermauw, W, Wybouw, N, Van Leeuwen, T, Chruszcz, M.
登録日2023-04-11
公開日2024-04-17
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Crystal structure of TuUGT202A2 (Tetur22g00270) in complex with quercetin
To Be Published
8SGG
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Crystal structure of Cy137D09, a monoclonal antibody isolated from macaques immunized with an Epstein-Barr virus glycoprotein 350 (gp350) nanoparticle vaccine
分子名称: Cy137D09 Fab heavy chain, Cy137D09 Fab light chain, GLYCEROL
著者Joyce, M.G, Jensen, J.L, Chen, W.H, Kanekiyo, M.
登録日2023-04-12
公開日2024-04-17
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Crystal structure of Cy137D09, a monoclonal antibody isolated from macaques immunized with an Epstein-Barr virus glycoprotein 350 (gp350) nanoparticle vaccine
To Be Published
3IH4
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TM1030 crystallized at 277K
分子名称: Transcriptional regulator, TetR family
著者Koclega, K.D, Chruszcz, M, Bujacz, G, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2009-07-29
公開日2009-08-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献'Hot' macromolecular crystals.
Cryst.Growth Des., 10, 2010
8S9Z
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Mpro inhibitors of SARS-CoV-2
分子名称: 3C-like proteinase nsp5, Mpro inhibitor
著者Blankenship, L.R, Liu, W.R.
登録日2023-03-30
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of MPI89 with Mpro of SARS-CoV-2 at 1.85A resolution.
To Be Published
7V6V
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trimolecular G-quadruplexes consists of a hairpin motif and two short chains
分子名称: DNA (5'-D(*CP*AP*GP*GP*GP*AP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*GP*GP*GP*A)-3')
著者Zhang, N, Jing, H.T, Hu, W.X.
登録日2021-08-20
公開日2023-02-08
最終更新日2024-05-15
実験手法SOLID-STATE NMR
主引用文献Conversion to Trimolecular G-Quadruplex by Spontaneous Hoogsteen Pairing-Based Strand Displacement Reaction between Bimolecular G-Quadruplex and Double G-Rich Probes.
J.Am.Chem.Soc., 2023
1NKQ
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BU of 1nkq by Molmil
Crystal structure of yeast ynq8, a fumarylacetoacetate hydrolase family protein
分子名称: ACETIC ACID, CALCIUM ION, Hypothetical 28.8 kDa protein in PSD1-SKO1 intergenic region, ...
著者Eswaramoorthy, S, Kumaran, D, Daniels, B, Studier, F.W, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2003-01-03
公開日2004-06-15
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crtystal Structure of Yeast Hypothetical Protein YNQ8_YEAST
To be Published
4DYJ
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BU of 4dyj by Molmil
Crystal structure of a broad specificity amino acid racemase (Bar) within internal aldimine linkage
分子名称: GLYCEROL, SULFATE ION, broad specificity amino acid racemase
著者Wang, W.C, Wu, H.M.
登録日2012-02-29
公開日2013-03-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal structures of lysine-preferred racemases, the non-antibiotic selectable markers for transgenic plants
Plos One, 7, 2012
4E20
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Structure of mouse Tyk-2 complexed to a 3-aminoindazole inhibitor
分子名称: N-[4-(3-amino-1H-indazol-5-yl)phenyl]-3-chlorobenzenesulfonamide, Non-receptor tyrosine-protein kinase TYK2
著者Argiriadi, M.A, Talanian, R.V, Borhani, D.W.
登録日2012-03-07
公開日2012-10-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Enabling structure-based drug design of Tyk2 through co-crystallization with a stabilizing aminoindazole inhibitor.
Bmc Struct.Biol., 12, 2012
1EZQ
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CRYSTAL STRUCTURE OF HUMAN COAGULATION FACTOR XA COMPLEXED WITH RPR128515
分子名称: 3-[(3'-AMINOMETHYL-BIPHENYL-4-CARBONYL)-AMINO]-2-(3-CARBAMIMIDOYL-BENZYL)-BUTYRIC ACID METHYL ESTER, CALCIUM ION, COAGULATION FACTOR XA
著者Maignan, S, Guilloteau, J.P, Pouzieux, S, Choi-Sledeski, Y.M, Becker, M.R, Klein, S.I, Ewing, W.R, Pauls, H.W, Spada, A.P, Mikol, V.
登録日2000-05-11
公開日2000-09-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of human factor Xa complexed with potent inhibitors.
J.Med.Chem., 43, 2000
8SPQ
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SpRY-Cas9:gRNA complex targeting TGG PAM DNA
分子名称: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, NTS, ...
著者Hibshman, G.N, Bravo, J.P.K, Taylor, D.W.
登録日2023-05-03
公開日2024-05-01
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
7VS2
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secreted fungal effector protein MoErs1
分子名称: MoErs1
著者Wang, F.F, Xing, W.M.
登録日2021-10-25
公開日2023-08-02
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Targeting Magnaporthe oryzae effector MoErs1 and host papain-like protease OsRD21 interaction to combat rice blast.
Nat.Plants, 2024
8FBL
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Human PAC in nanodisc at pH 4.0 with PI(4,5)P2 diC8
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Proton-activated chloride channel, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Ruan, Z, Lu, W.
登録日2022-11-29
公開日2023-02-01
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Inhibition of the proton-activated chloride channel PAC by PIP 2.
Elife, 12, 2023
2ZX8
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alpha-L-fucosidase complexed with inhibitor, F10-2C-O
分子名称: Alpha-L-fucosidase, putative, N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}-1-benzofuran-2-carboxamide
著者Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J.
登録日2008-12-19
公開日2009-12-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
Angew.Chem.Int.Ed.Engl., 49, 2010
5AY7
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A psychrophilic glycoside hydrolase family 10 endo-beta-1,4-xylanase
分子名称: xylanase
著者Zheng, Y, Li, Y, Liu, W, Guo, R.T.
登録日2015-08-10
公開日2016-02-24
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural insight into potential cold adaptation mechanism through a psychrophilic glycoside hydrolase family 10 endo-beta-1,4-xylanase.
J.Struct.Biol., 193, 2016
3IO8
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BimL12F in complex with Bcl-xL
分子名称: Bcl-2-like protein 1, Bcl-2-like protein 11, ZINC ION
著者Colman, P.M, Lee, E.F, Fairlie, W.D, Smith, B.J, Czabotar, P.E, Yang, H, Sleebs, B.E, Lessene, G.
登録日2009-08-14
公開日2009-09-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Conformational changes in Bcl-2 pro-survival proteins determine their capacity to bind ligands.
J.Biol.Chem., 284, 2009
1F0S
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Crystal Structure of Human Coagulation Factor XA Complexed with RPR208707
分子名称: CALCIUM ION, COAGULATION FACTOR XA, THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [2-OXO-1-(1H-PYRROLO[2,3-C]PYRIDIN-2-YLMETHYL)-PYRROLIDIN-3-YL]-AMIDE
著者Maignan, S, Guilloteau, J.P, Pouzieux, S, Choi-Sledeski, Y.M, Becker, M.R, Klein, S.I, Ewing, W.R, Pauls, H.W, Spada, A.P, Mikol, V.
登録日2000-05-17
公開日2000-09-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of human factor Xa complexed with potent inhibitors.
J.Med.Chem., 43, 2000

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