1EZQ

CRYSTAL STRUCTURE OF HUMAN COAGULATION FACTOR XA COMPLEXED WITH RPR128515

Summary for 1EZQ

• Entry DOI: 10.2210/pdb1ezq/pdb
• Related: 1F0R 1F0S 1F0T 1F0U
• Descriptor: COAGULATION FACTOR XA, CALCIUM ION, 3-[(3'-AMINOMETHYL-BIPHENYL-4-CARBONYL)-AMINO]-2-(3-CARBAMIMIDOYL-BENZYL)-BUTYRIC ACID METHYL ESTER, ... (5 entities in total)
• Functional Keywords: hydrolase
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P00742 P00742
• Total number of polymer chains: 2
• Total formula weight: 44260.02

Authors

Maignan, S.,Guilloteau, J.P.,Pouzieux, S.,Choi-Sledeski, Y.M.,Becker, M.R.,Klein, S.I.,Ewing, W.R.,Pauls, H.W.,Spada, A.P.,Mikol, V. (deposition date: 2000-05-11, release date: 2000-09-20, Last modification date: 2024-03-13)

• Primary citation: Maignan, S.,Guilloteau, J.P.,Pouzieux, S.,Choi-Sledeski, Y.M.,Becker, M.R.,Klein, S.I.,Ewing, W.R.,Pauls, H.W.,Spada, A.P.,Mikol, V.; Crystal structures of human factor Xa complexed with potent inhibitors.; J.Med.Chem., 43:3226-3232, 2000; PubMed: 10966741; DOI: 10.1021/jm000940u

Experimental method

X-RAY DIFFRACTION (2.2 Å)