2ZX8

alpha-L-fucosidase complexed with inhibitor, F10-2C-O

Summary for 2ZX8

Related1hl8 2zwy 2zwz 2ZX5 2ZX6 2ZX7 2ZX9 2ZXA 2ZXB 2ZXD
DescriptorAlpha-L-fucosidase, putative, N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}-1-benzofuran-2-carboxamide (3 entities in total)
Functional Keywordstim barrel, hydrolase
Biological sourceThermotoga maritima
Total number of polymer chains2
Total molecular weight106842.52
Authors
Wu, H.-J.,Ko, T.-P.,Ho, C.-W.,Lin, C.-H.,Wang, A.H.-J. (deposition date: 2008-12-19, release date: 2009-12-08, Last modification date: 2017-10-11)
Primary citation
Wu, H.J.,Ho, C.W.,Ko, T.P.,Popat, S.D.,Lin, C.H.,Wang, A.H.
Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
Angew.Chem.Int.Ed.Engl., 49:337-340, 2010
PubMed: 19967696 (PDB entries with the same primary citation)
DOI: 10.1002/anie.200905597
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.33 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2097 0.3% 2.9% 4.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
170172
PDB entries from 2020-10-21