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PDB: 34568 件
1VKT
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HUMAN INSULIN TWO DISULFIDE MODEL, NMR, 10 STRUCTURES
分子名称: INSULIN
著者Hua, Q.X, Hu, S.Q, Frank, B.H, Jia, W.H, Chu, Y.C, Wang, S.H, Burke, G.T, Katsoyannis, P.G, Weiss, M.A.
登録日1996-10-14
公開日1997-04-01
最終更新日2021-11-03
実験手法SOLUTION NMR
主引用文献Mapping the functional surface of insulin by design: structure and function of a novel A-chain analogue.
J.Mol.Biol., 264, 1996
4BSO
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BU of 4bso by Molmil
Crystal structure of R-spondin 1 (Fu1Fu2) - Native
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, R-SPONDIN-1
著者Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P.
登録日2013-06-11
公開日2013-06-19
最終更新日2013-07-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3, 2013
4XM5
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C. glabrata Slx1.
分子名称: CHLORIDE ION, Structure-specific endonuclease subunit SLX1, ZINC ION
著者Gaur, V, Wyatt, H.D.M, Komorowska, W, Szczepanowski, R.H, de Sanctis, D, Gorecka, K.M, West, S.C, Nowotny, M.
登録日2015-01-14
公開日2015-03-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Structural and Mechanistic Analysis of the Slx1-Slx4 Endonuclease.
Cell Rep, 10, 2015
6MPW
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BU of 6mpw by Molmil
De Novo Design of membrane protein--mini-eVgL membrane protein, C2221 form-1
分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, mini-eVgL membrane protein
著者Mravic, M, Liu, L, DeGrado, W.F.
登録日2018-10-08
公開日2019-04-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Packing of apolar side chains enables accurate design of highly stable membrane proteins.
Science, 363, 2019
4BST
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BU of 4bst by Molmil
Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in P6122 crystal form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, R-SPONDIN-1, ...
著者Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P.
登録日2013-06-11
公開日2013-06-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3, 2013
1W85
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The crystal structure of pyruvate dehydrogenase E1 bound to the peripheral subunit binding domain of E2
分子名称: DI(HYDROXYETHYL)ETHER, DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE, MAGNESIUM ION, ...
著者Frank, R.A.W, Pratap, J.V, Pei, X.Y, Perham, R.N, Luisi, B.F.
登録日2004-09-16
公開日2004-11-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A molecular switch and proton wire synchronize the active sites in thiamine enzymes.
Science, 306, 2004
4CEH
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Crystal structure of AddAB with a forked DNA substrate
分子名称: ATP-DEPENDENT HELICASE/DEOXYRIBONUCLEASE SUBUNIT B, ATP-DEPENDENT HELICASE/NUCLEASE SUBUNIT A, DNA, ...
著者Krajewski, W.W, Wilkinson, M, Fu, X, Cronin, N.B, Wigley, D.
登録日2013-11-11
公開日2014-03-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Structural Basis for Translocation by Addab Helicase-Nuclease and its Arrest at Chi Sites.
Nature, 508, 2014
1FS4
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BU of 1fs4 by Molmil
Structures of glycogen phosphorylase-inhibitor complexes and the implications for structure-based drug design
分子名称: 1-DEOXY-1-METHOXYCARBAMIDO-BETA-D-GLUCO-2-HEPTULOPYRANOSONAMIDE, GLYCOGEN PHOSPHORYLASE, PYRIDOXAL-5'-PHOSPHATE
著者Watson, K.A, Tsitsanou, K.E, Gregoriou, M, Zographos, S.E, Skamnaki, V.T, Oikonomakos, N.G, Fleet, G.W, Johnson, L.N.
登録日2000-09-08
公開日2000-10-04
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase.
Proteins, 61, 2005
1VPC
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C-TERMINAL DOMAIN (52-96) OF THE HIV-1 REGULATORY PROTEIN VPR, NMR, 1 STRUCTURE
分子名称: VPR PROTEIN
著者Schueler, W, De Rocquigny, H, Baudat, Y, Sire, J, Roques, B.P.
登録日1998-02-20
公開日1999-03-23
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR structure of the (52-96) C-terminal domain of the HIV-1 regulatory protein Vpr: molecular insights into its biological functions.
J.Mol.Biol., 285, 1999
4C5S
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BU of 4c5s by Molmil
Structural Investigations into the Stereochemistry and Activity of a Phenylalanine-2,3-Aminomutase from Taxus chinensis
分子名称: (3S)-3-amino-2,2-difluoro-3-phenylpropanoic acid, PHENYLALANINE AMMONIA-LYASE
著者Wybenga, G.G, Szymanski, W, Wu, B, Feringa, B.L, Janssen, D.B, Dijkstra, B.W.
登録日2013-09-16
公開日2014-05-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Investigations Into the Stereochemistry and Activity of a Phenylalanine-2,3-Aminomutase from Taxus Chinensis.
Biochemistry, 53, 2014
4H33
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Crystal structure of a voltage-gated K+ channel pore module in a closed state in lipid membranes, tetragonal crystal form
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Lmo2059 protein, POTASSIUM ION
著者Santos, J.S, Asmar-Rovira, G.A, Han, G.W, Liu, W, Syeda, R, Cherezov, V, Baker, K.A, Stevens, R.C, Montal, M.
登録日2012-09-13
公開日2012-11-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structure of a Voltage-gated K+ Channel Pore Module in a Closed State in Lipid Membranes.
J.Biol.Chem., 287, 2012
4BVY
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BU of 4bvy by Molmil
Crystal structure of the AIMP3-MRS N-terminal domain complex
分子名称: EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1, METHIONINE--TRNA LIGASE, CYTOPLASMIC
著者Cho, H.Y, Seo, W.W, Cho, H.J, Kang, B.S.
登録日2013-06-29
公開日2014-07-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.992 Å)
主引用文献Crystal Structure of the Aimp3-Mrs N-Terminal Domain Complex
To be Published
4H9S
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Complex structure 6 of DAXX/H3.3(sub7)/H4
分子名称: Death domain-associated protein 6, Histone H3.3, Histone H4, ...
著者Elsasser, S.J, Huang, H, Lewis, P.W, Chin, J.W, Allis, D.C, Patel, D.J.
登録日2012-09-24
公開日2012-10-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献DAXX chaperone envelops an H3.3/H4 dimer dictating H3.3-specific read out
To be Published
4XBF
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BU of 4xbf by Molmil
Structure of LSD1:CoREST in complex with ssRNA
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Lysine-specific histone demethylase 1A, ...
著者Luka, Z, Loukachevitch, L.V, Martin, W.J, Wagner, C, Reiter, N.J.
登録日2014-12-16
公開日2016-04-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.803 Å)
主引用文献G-quadruplex RNA binding and recognition by the lysine-specific histone demethylase-1 enzyme.
RNA, 22, 2016
1JIJ
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BU of 1jij by Molmil
Crystal structure of S. aureus TyrRS in complex with SB-239629
分子名称: [2-AMINO-3-(4-HYDROXY-PHENYL)-PROPIONYLAMINO]-(1,3,4,5-TETRAHYDROXY-4-HYDROXYMETHYL-PIPERIDIN-2-YL)- ACETIC ACID, tyrosyl-tRNA synthetase
著者Qiu, X, Janson, C.A, Smith, W.W, Jarvest, R.L.
登録日2001-07-02
公開日2001-10-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of Staphylococcus aureus tyrosyl-tRNA synthetase in complex with a class of potent and specific inhibitors.
Protein Sci., 10, 2001
2BTN
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BU of 2btn by Molmil
Crystal Structure and Catalytic Mechanism of the Quorum-Quenching N- Acyl Homoserine Lactone Hydrolase
分子名称: AIIA-LIKE PROTEIN, GLYCEROL, ZINC ION
著者Kim, M.H, Choi, W.C, Kang, H.O, Lee, J.S, Kang, B.S, Kim, K.J, Derewenda, Z.S, Oh, T.K, Lee, C.H, Lee, J.K.
登録日2005-06-03
公開日2005-12-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Molecular Structure and Catalytic Mechanism of a Quorum-Quenching N-Acyl-L-Homoserine Lactone Hydrolase.
Proc.Natl.Acad.Sci.USA, 102, 2005
4Y14
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Structure of protein tyrosine phosphatase 1B complexed with inhibitor (PTP1B:CPT157633)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-bromo-4-[difluoro(phosphono)methyl]-N-methyl-Nalpha-(methylsulfonyl)-L-phenylalaninamide, CHLORIDE ION, ...
著者Choy, M.S, Connors, C, Page, R, Peti, W.
登録日2015-02-06
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.898 Å)
主引用文献PTP1B inhibition suggests a therapeutic strategy for Rett syndrome.
J.Clin.Invest., 125, 2015
2BNN
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The structure of Hydroxypropylphosphonic acid epoxidase from S. wedmorenis in complex with fosfomycin
分子名称: EPOXIDASE, FOSFOMYCIN, ZINC ION
著者McLuskey, K, Cameron, S, Hunter, W.N.
登録日2005-03-29
公開日2005-10-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and Reactivity of Hydroxypropylphosphonic Acid Epoxidase in Fosfomycin Biosynthesis by a Cation- and Flavin-Dependent Mechanism.
Proc.Natl.Acad.Sci.USA, 102, 2005
5LOH
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BU of 5loh by Molmil
Kinase domain of human Greatwall
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, STAUROSPORINE, ...
著者Rajasekaran, M.B, Pearl, L.H, Oliver, A.W.
登録日2016-08-09
公開日2016-09-07
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A first generation inhibitor of human Greatwall kinase, enabled by structural and functional characterisation of a minimal kinase domain construct.
Oncotarget, 7, 2016
4XVK
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Binary complex of human polymerase nu and DNA with the finger domain closed
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (5'-D(*GP*AP*TP*CP*TP*GP*AP*CP*GP*CP*TP*AP*CP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*GP*TP*AP*GP*CP*GP*TP*CP*A)-3'), ...
著者Lee, Y.-S, Yang, W.
登録日2015-01-27
公開日2015-03-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis.
Nat.Struct.Mol.Biol., 22, 2015
4XAO
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Crystal structure of the hPXR-LBD obtained in presence of the pesticide trans-nonachlor
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ISOPROPYL ALCOHOL, Nuclear receptor subfamily 1 group I member 2
著者Delfosse, V, Huet, T, Bourguet, W.
登録日2014-12-15
公開日2015-09-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Synergistic activation of human pregnane X receptor by binary cocktails of pharmaceutical and environmental compounds.
Nat Commun, 6, 2015
3ZTS
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BU of 3zts by Molmil
Hexagonal form P6122 of the Aquifex aeolicus nucleoside diphosphate kinase (FINAL STAGE OF RADIATION DAMAGE)
分子名称: NUCLEOSIDE DIPHOSPHATE KINASE
著者Boissier, F, Georgescauld, F, Moynie, L, Dupuy, J.-W, Sarger, C, Podar, M, Lascu, I, Giraud, M.-F, Dautant, A.
登録日2011-07-12
公開日2012-03-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献An Inter-Subunit Disulphide Bridge Stabilizes the Tetrameric Nucleoside Diphosphate Kinase of Aquifex Aeolicus
Proteins, 80, 2012
6NAW
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Crystal structure of Neisseria meningitidis ClpP E58A activated mutant
分子名称: ATP-dependent Clp protease proteolytic subunit
著者Mabanglo, M.F, Houry, W.A.
登録日2018-12-06
公開日2019-11-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.399 Å)
主引用文献ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores.
Commun Biol, 2, 2019
4XZC
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The crystal structure of Kupe virus nucleoprotein
分子名称: Nucleoprotein
著者Guo, Y, Wang, W, Liu, X, Wang, X, Wang, J, Huo, T, Liu, B.
登録日2015-02-04
公開日2015-09-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Structural and Functional Diversity of Nairovirus-Encoded Nucleoproteins.
J.Virol., 89, 2015
4IPL
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BU of 4ipl by Molmil
The crystal structure of 6-phospho-beta-glucosidase BglA-2 from Streptococcus pneumoniae
分子名称: 6-phospho-beta-glucosidase, GLYCEROL
著者Yu, W.L, Jiang, Y.L, Andreas, P, Cheng, W, Bai, X.H, Ren, Y.M, Thompsonn, J, Zhou, C.Z, Chen, Y.X.
登録日2013-01-10
公開日2013-04-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.004 Å)
主引用文献Structural insights into the substrate specificity of a 6-phospho-&[beta]-glucosidase BglA-2 from Streptococcus pneumoniae TIGR4
J.Biol.Chem., 288, 2013

224004

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