3L43
 
 | | Crystal structure of the dynamin 3 GTPase domain bound with GDP | | 分子名称: | Dynamin-3, GUANOSINE-5'-DIPHOSPHATE, UNKNOWN ATOM OR ION | | 著者 | Yang, S, Tempel, W, Tong, Y, Nedyalkova, L, Guan, X, Crombet, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2009-12-18 | | 公開日 | 2010-01-19 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Crystal structure of the dynamin 3 GTPase domain bound with GDP
to be published
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3KGF
 | | The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis complexed with phenylalanine and tryptophan | | 分子名称: | CHLORIDE ION, GLYCEROL, MANGANESE (II) ION, ... | | 著者 | Parker, E.J, Jameson, G.B, Jiao, W, Webby, C.J, Baker, E.N, Baker, H.M, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) | | 登録日 | 2009-10-29 | | 公開日 | 2010-07-28 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis
J.Biol.Chem., 285, 2010
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3GGF
 | | Crystal structure of human Serine/threonine-protein kinase MST4 in complex with an quinazolin | | 分子名称: | CADMIUM ION, Serine/threonine-protein kinase MST4, [4-({4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]QUINAZOLIN-2-YL}IMINO)CYCLOHEXA-2,5-DIEN-1-YL]ACETONITRILE | | 著者 | Chaikuad, A, Rellos, P, Eidarus, S, Das, S, Pike, A.C.W, Sethi, R, Fedorov, O, Savitsky, P, Roos, A.K, Filippakopoulos, P, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, von Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2009-02-27 | | 公開日 | 2009-03-24 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural comparison of human mammalian ste20-like kinases
Plos One, 5, 2010
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1V0Z
 | | Structure of Neuraminidase from English duck subtype N6 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Rudino-Pinera, E, Tunnah, P, Crennell, S.J, Webster, R.G, Laver, W.G, Garman, E.F. | | 登録日 | 2004-03-12 | | 公開日 | 2006-01-25 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | The Crystal Structure of Influenza Type a Virus Neuraminidase of the N6 Subtype at 1.85 A Resolution
To be Published
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2X7J
 | | Structure of the menaquinone biosynthesis protein MenD from Bacillus subtilis | | 分子名称: | 1,2-ETHANEDIOL, 2-SUCCINYL-5-ENOLPYRUVYL-6-HYDROXY-3-CYCLOHEXENE -1-CARBOXYLATE SYNTHASE, MANGANESE (II) ION, ... | | 著者 | Dawson, A, Chen, M, Fyfe, P.K, Guo, Z, Hunter, W.N. | | 登録日 | 2010-03-01 | | 公開日 | 2010-07-14 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structure and Reactivity of Bacillus Subtilis Mend Catalyzing the First Committed Step in Menaquinone Biosynthesis.
J.Mol.Biol., 401, 2010
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3KMB
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7XWO
 | | Neurokinin A bound to active human neurokinin 2 receptor in complex with G324 | | 分子名称: | G324, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Sun, W.J, Yuan, Q.N, Zhang, H.H, Yang, F, Ling, S.L, Lv, P, Eric, X, Tian, C.L, Yin, W.C, Shi, P. | | 登録日 | 2022-05-26 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural insights into the activation of neurokinin 2 receptor by neurokinin A.
Cell Discov, 8, 2022
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1FVA
 | | CRYSTAL STRUCTURE OF BOVINE METHIONINE SULFOXIDE REDUCTASE | | 分子名称: | PEPTIDE METHIONINE SULFOXIDE REDUCTASE | | 著者 | Lowther, W.T, Brot, N, Weissbach, H, Matthews, B.W. | | 登録日 | 2000-09-19 | | 公開日 | 2000-11-08 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure and mechanism of peptide methionine sulfoxide reductase, an "anti-oxidation" enzyme.
Biochemistry, 39, 2000
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1UXM
 | | A4V mutant of human SOD1 | | 分子名称: | COPPER (II) ION, SUPEROXIDE DISMUTASE [CU-ZN], ZINC ION | | 著者 | Hough, M.A, Grossmann, J.G, Antonyuk, S.V, Strange, R.W, Doucette, P.A, Rodriguez, J.A, Whitson, L.J, Hart, P.J, Hayward, L.J, Valentine, J.S, Hasnain, S.S. | | 登録日 | 2004-02-26 | | 公開日 | 2004-03-19 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Dimer Destabilization in Superoxide Dismutase May Result in Disease-Causing Properties: Structures of Motor Neuron Disease Mutants
Proc.Natl.Acad.Sci.USA, 101, 2004
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1PU0
 | | Structure of Human Cu,Zn Superoxide Dismutase | | 分子名称: | COPPER (I) ION, SULFATE ION, Superoxide dismutase [Cu-Zn], ... | | 著者 | DiDonato, M, Craig, L, Huff, M.E, Thayer, M.M, Cardoso, R.M.F, Kassmann, C.J, Lo, T.P, Bruns, C.K, Powers, E.T, Kelly, J.W, Getzoff, E.D, Tainer, J.A. | | 登録日 | 2003-06-23 | | 公開日 | 2003-09-09 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | ALS Mutants of Human Superoxide Dismutase Form Fibrous Aggregates Via Framework Destabilization
J.Mol.Biol., 332, 2003
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1Q5R
 | | The Rhodococcus 20S proteasome with unprocessed pro-peptides | | 分子名称: | proteasome alpha-type subunit 1, proteasome beta-type subunit 1 | | 著者 | Kwon, Y.D, Nagy, I, Adams, P.D, Baumeister, W, Jap, B.K. | | 登録日 | 2003-08-08 | | 公開日 | 2003-12-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Crystal structures of the Rhodococcus proteasome with and without its pro-peptides: implications for the role of the pro-peptide in proteasome assembly.
J.Mol.Biol., 335, 2004
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1Q47
 | | Structure of the Semaphorin 3A Receptor-Binding Module | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Semaphorin 3A | | 著者 | Antipenko, A, Himanen, J.-P, van Leyen, K, Nardi-Dei, V, Lesniak, J, Barton, W.A, Rajashankar, K.R, Lu, M, Hoemme, C, Puschel, A, Nikolov, D. | | 登録日 | 2003-08-01 | | 公開日 | 2004-08-03 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of the semaphorin-3A receptor binding module.
Neuron, 39, 2003
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4EZ9
 | | Bacillus DNA Polymerase I Large Fragment Complex 2 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... | | 著者 | Wang, W, Beese, L.S. | | 登録日 | 2012-05-02 | | 公開日 | 2013-07-24 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Structures of a High-fidelity DNA Polymerase
to be published
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3KWO
 | | Crystal Structure of Putative Bacterioferritin from Campylobacter jejuni | | 分子名称: | 1,4-BUTANEDIOL, ACETIC ACID, GLYCEROL, ... | | 著者 | Kim, Y, Gu, M, Papazisi, L, Anderson, W, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2009-12-01 | | 公開日 | 2010-01-19 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.985 Å) | | 主引用文献 | Crystal Structure of Putative Bacterioferritin from Campylobacter jejuni
To be Published
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4F2S
 | | DNA Polymerase I Large Fragment complex 4 | | 分子名称: | CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), ... | | 著者 | Wang, W, Beese, L.S. | | 登録日 | 2012-05-08 | | 公開日 | 2013-07-24 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.651 Å) | | 主引用文献 | Structures of a High-fidelity DNA Polymerase
to be published
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4NGE
 | | Crystal Structure of Human Presequence Protease in Complex with Amyloid-beta (1-40) | | 分子名称: | ACETATE ION, Beta-amyloid protein 40, GLYCEROL, ... | | 著者 | King, J.V, Liang, W.G, Tang, W.J. | | 登録日 | 2013-11-01 | | 公開日 | 2014-05-14 | | 最終更新日 | 2014-07-23 | | 実験手法 | X-RAY DIFFRACTION (2.704 Å) | | 主引用文献 | Molecular basis of substrate recognition and degradation by human presequence protease.
Structure, 22, 2014
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4F3O
 | | DNA Polymerase I Large Fragment Complex 5 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*C*AP*TP*GP*AP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... | | 著者 | Wang, W, Beese, L.S. | | 登録日 | 2012-05-09 | | 公開日 | 2013-07-24 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Structures of a High-fidelity DNA Polymerase
to be published
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4EZA
 | | Crystal structure of the atypical phosphoinositide (aPI) binding domain of IQGAP2 | | 分子名称: | Ras GTPase-activating-like protein IQGAP2 | | 著者 | Van Aalten, D.M.F, Dixon, M.J, Gray, A, Schenning, M, Agacan, M, Leslie, N.R, Downes, C.P, Batty, I.H, Nedyalkova, L, Tempel, W, Tong, Y, Zhong, N, Crombet, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2012-05-02 | | 公開日 | 2012-05-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | IQGAP Proteins Reveal an Atypical Phosphoinositide (aPI) Binding Domain with a Pseudo C2 Domain Fold.
J.Biol.Chem., 287, 2012
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4MPL
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3QV9
 | | Crystal structure of Trypanosoma cruzi pyruvate kinase(TcPYK)in complex with ponceau S. | | 分子名称: | 3-hydroxy-4-[(E)-{2-sulfo-4-[(E)-(4-sulfophenyl)diazenyl]phenyl}diazenyl]naphthalene-2,7-disulfonic acid, PHOSPHATE ION, POTASSIUM ION, ... | | 著者 | Morgan, H.P, Auld, D.S, McNae, I.W, Nowicki, M.W, Michels, P.A.M, Fothergill-Gilmore, L.A, Walkinshaw, M.D. | | 登録日 | 2011-02-25 | | 公開日 | 2011-07-06 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The trypanocidal drug suramin and other trypan blue mimetics are inhibitors of pyruvate kinases and bind to the adenosine site.
J.Biol.Chem., 286, 2011
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2QNF
 | | Crystal structure of T4 Endonuclease VII H43N mutant in complex with heteroduplex DNA containing base mismatches | | 分子名称: | DNA (5'-D(*DCP*DAP*DCP*DAP*DTP*DCP*DGP*DAP*DTP*DGP*DGP*DAP*DGP*DCP*DCP*DG)-3'), DNA (5'-D(*DCP*DAP*DCP*DAP*DTP*DCP*DGP*DAP*DTP*DGP*DGP*DAP*DGP*DCP*DGP*DC)-3'), DNA (5'-D(*DCP*DGP*DGP*DCP*DTP*DCP*DCP*DAP*DTP*DCP*DGP*DAP*DTP*DGP*DTP*DG)-3'), ... | | 著者 | Biertumpfel, C, Yang, W, Suck, D. | | 登録日 | 2007-07-18 | | 公開日 | 2008-01-29 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of T4 endonuclease VII resolving a Holliday junction.
Nature, 449, 2007
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4F8R
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3GE1
 | | 2.7 Angstrom Crystal Structure of Glycerol Kinase (glpK) from Staphylococcus aureus in Complex with ADP and Glycerol | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... | | 著者 | Minasov, G, Brunzelle, J, Skarina, T, Onopriyenko, O, Peterson, S.N, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2009-02-24 | | 公開日 | 2009-03-24 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | 2.7 Angstrom Crystal Structure of Glycerol Kinase (glpK) from Staphylococcus aureus in Complex with ADP and Glycerol
To be Published
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4MW0
 | | Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(3,5-dichlorobenzyl)amino]propyl}-3-(2-hydroxyphenyl)urea (Chem 1392) | | 分子名称: | 1-{3-[(3,5-dichlorobenzyl)amino]propyl}-3-(2-hydroxyphenyl)urea, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. | | 登録日 | 2013-09-24 | | 公開日 | 2014-04-30 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | | 主引用文献 | Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness.
Plos Negl Trop Dis, 8, 2014
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1VCB
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