4EZA
Crystal structure of the atypical phosphoinositide (aPI) binding domain of IQGAP2
Summary for 4EZA
Entry DOI | 10.2210/pdb4eza/pdb |
Descriptor | Ras GTPase-activating-like protein IQGAP2 (2 entities in total) |
Functional Keywords | gap, structural genomics consortium, sgc, signaling protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 26464.69 |
Authors | Van Aalten, D.M.F.,Dixon, M.J.,Gray, A.,Schenning, M.,Agacan, M.,Leslie, N.R.,Downes, C.P.,Batty, I.H.,Nedyalkova, L.,Tempel, W.,Tong, Y.,Zhong, N.,Crombet, L.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Bochkarev, A.,Park, H.,Structural Genomics Consortium (SGC) (deposition date: 2012-05-02, release date: 2012-05-16, Last modification date: 2024-02-28) |
Primary citation | Dixon, M.J.,Gray, A.,Schenning, M.,Agacan, M.,Tempel, W.,Tong, Y.,Nedyalkova, L.,Park, H.W.,Leslie, N.R.,van Aalten, D.M.,Downes, C.P.,Batty, I.H. IQGAP Proteins Reveal an Atypical Phosphoinositide (aPI) Binding Domain with a Pseudo C2 Domain Fold. J.Biol.Chem., 287:22483-22496, 2012 Cited by PubMed: 22493426DOI: 10.1074/jbc.M112.352773 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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