3LO1
 
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4XYN
 | | X-ray structure of Ca(2+)-S100B with human RAGE-derived W61 peptide | | 分子名称: | CALCIUM ION, Protein S100-B, Receptor for advanced glycation endproducts-derived peptide (W61) | | 著者 | Jensen, J.L, Indurthi, V.S.K, Neau, D, Vetter, S.W, Colbert, C.L. | | 登録日 | 2015-02-02 | | 公開日 | 2015-05-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Structural insights into the binding of the human receptor for advanced glycation end products (RAGE) by S100B, as revealed by an S100B-RAGE-derived peptide complex.
Acta Crystallogr.,Sect.D, 71, 2015
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6FBV
 | | Single particle cryo em structure of Mycobacterium tuberculosis RNA polymerase in complex with Fidaxomicin | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Das, K, Lin, W, Ebright, E. | | 登録日 | 2017-12-19 | | 公開日 | 2018-02-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | | 主引用文献 | Structural Basis of Transcription Inhibition by Fidaxomicin (Lipiarmycin A3).
Mol. Cell, 70, 2018
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6EYN
 | | Structure of the 8D6 (anti-IgE) Fab | | 分子名称: | 1,2-ETHANEDIOL, 8D6 Fab heavy chain, 8D6 Fab light chain, ... | | 著者 | Chen, J.B, Ramadani, F, Pang, M.O.Y, Beavil, R.L, Holdom, M.D, Mitropoulou, A.N, Beavil, A.J, Gould, H.J, Chang, T.W, Sutton, B.J, McDonnell, J.M, Davies, A.M. | | 登録日 | 2017-11-13 | | 公開日 | 2018-08-15 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for selective inhibition of immunoglobulin E-receptor interactions by an anti-IgE antibody.
Sci Rep, 8, 2018
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7T8S
 | | Light Harvesting complex phycoerythrin PE 566, from the cryptophyte Cryptomonas pyrenoidifera | | 分子名称: | Bilin 584 (doubly linked), Bilin 584 (single linked), Bilin 618 (single linked), ... | | 著者 | Michie, K.A, Harrop, S.J, Rathbone, H.W, Wilk, K.E, Curmi, P.M.G. | | 登録日 | 2021-12-17 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Molecular structures reveal the origin of spectral variation in cryptophyte light harvesting antenna proteins.
Protein Sci., 32, 2023
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6M05
 | | Trimolecular G-quadruplex | | 分子名称: | DNA (5'-D(*GP*TP*TP*AP*GP*G)-3') | | 著者 | Jing, H.T, Fu, W.Q, Zhang, N. | | 登録日 | 2020-02-20 | | 公開日 | 2021-01-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structural study on the self-trimerization of d(GTTAGG) into a dynamic trimolecular G-quadruplex assembly preferentially in Na+ solution with a moderate K+ tolerance.
Nucleic Acids Res., 49, 2021
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5IJT
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8AJQ
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8B0J
 | | CryoEM structure of bacterial RNaseE.RapZ.GlmZ complex central to the control of cell envelope biogenesis | | 分子名称: | GlmZ small RNA, RNase adapter protein RapZ, Ribonuclease E | | 著者 | Islam, M.S, Hardwick, H.W, Chirgadze, D.Y, Luisi, B.F. | | 登録日 | 2022-09-07 | | 公開日 | 2022-10-05 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.99 Å) | | 主引用文献 | Structure of a bacterial ribonucleoprotein complex central to the control of cell envelope biogenesis.
Embo J., 42, 2023
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4XAP
 | | Crystal structure of aldo-keto reductase from Sinorhizobium meliloti 1021 | | 分子名称: | Aldo-keto reductase | | 著者 | Gasiorowska, O.A, Handing, K.B, Shabalin, I.G, Bonanno, J, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2014-12-15 | | 公開日 | 2014-12-31 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Crystal structure of aldo-keto reductase from Sinorhizobium meliloti 1021
to be published
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6F5D
 | | Trypanosoma brucei F1-ATPase | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP synthase gamma subunit, ATP synthase subunit alpha, ... | | 著者 | Montgomery, M.G, Gahura, O, Leslie, A.G.W, Zikova, A, Walker, J.E. | | 登録日 | 2017-12-01 | | 公開日 | 2018-02-21 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | ATP synthase fromTrypanosoma bruceihas an elaborated canonical F1-domain and conventional catalytic sites.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4X9V
 | | PLK-1 polo-box domain in complex with Bioactive Imidazolium-containing phosphopeptide macrocycle 3C | | 分子名称: | Phosphopeptide macrocycle 3C, Serine/threonine-protein kinase PLK1 | | 著者 | Grant, R.A, Qian, W.-J, Yaffe, M.B, Burke, T.R. | | 登録日 | 2014-12-11 | | 公開日 | 2015-07-29 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.429 Å) | | 主引用文献 | Neighbor-directed histidine N ( tau )-alkylation: A route to imidazolium-containing phosphopeptide macrocycles.
Biopolymers, 104, 2015
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1RK6
 | | The enzyme in complex with 50mM CdCl2 | | 分子名称: | ACETATE ION, CADMIUM ION, D-aminoacylase, ... | | 著者 | Lai, W.L, Chou, L.Y, Ting, C.Y, Tsai, Y.C, Liaw, S.H. | | 登録日 | 2003-11-20 | | 公開日 | 2004-04-20 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | The functional role of the binuclear metal center in D-aminoacylase: one-metal activation and second-metal attenuation.
J.Biol.Chem., 279, 2004
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7WRG
 | | Crystal structure of full-length kinesin-3 KLP-6 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein, MAGNESIUM ION | | 著者 | Wang, W.J, Ren, J.Q, Song, W.Y, Feng, W. | | 登録日 | 2022-01-26 | | 公開日 | 2022-08-10 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.16 Å) | | 主引用文献 | The architecture of kinesin-3 KLP-6 reveals a multilevel-lockdown mechanism for autoinhibition.
Nat Commun, 13, 2022
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2XKM
 | | Consensus structure of Pf1 filamentous bacteriophage from X-ray fibre diffraction and solid-state NMR | | 分子名称: | CAPSID PROTEIN G8P | | 著者 | Straus, S.K, P Scott, W.R, Schwieters, C.D, Marvin, D.A. | | 登録日 | 2010-07-09 | | 公開日 | 2010-11-24 | | 最終更新日 | 2023-12-20 | | 実験手法 | FIBER DIFFRACTION (3.3 Å), SOLID-STATE NMR | | 主引用文献 | Consensus Structure of Pf1 Filamentous Bacteriophage from X-Ray Fibre Diffraction and Solid-State NMR.
Eur.Biophys.J., 40, 2011
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1I7J
 | | CRYSTAL STRUCTURE OF 2'-O-ME(CGCGCG)2: AN RNA DUPLEX AT 1.19 A RESOLUTION. 2-METHYL-2,4-PENTANEDIOL AND MAGNESIUM BINDING. | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 5'-R(*(OMC)P*(OMG)P*(OMC)P*(OMG)P*(OMC)P*(OMG))-3', MAGNESIUM ION | | 著者 | Adamiak, D.A, Rypniewski, W.R, Milecki, J, Adamiak, R.W. | | 登録日 | 2001-03-09 | | 公開日 | 2001-09-21 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | | 主引用文献 | The 1.19 A X-ray structure of 2'-O-Me(CGCGCG)(2) duplex shows dehydrated RNA with 2-methyl-2,4-pentanediol in the minor groove.
Nucleic Acids Res., 29, 2001
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4IJL
 | | Fragment-based Discovery of Protein-Protein Interaction Inhibitors of Replication Protein A | | 分子名称: | Replication protein A 70 kDa DNA-binding subunit, {[5-(3-chloro-1-benzothiophen-2-yl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid | | 著者 | Feldkamp, M.D, Patrone, J.D, Kennedy, J.P, Frank, A.O, Vangamudi, B, Pelz, N.F, Rossanese, O.W, Waterson, A.G, Fesik, S.W, Chazin, W.J. | | 登録日 | 2012-12-21 | | 公開日 | 2013-08-14 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Discovery of Protein-Protein Interaction Inhibitors of Replication Protein A.
ACS MED.CHEM.LETT., 4, 2013
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2VZE
 | | Crystal structure of human acyl-CoA synthetase medium-chain family member 2A (L64P mutation) in complex with AMP | | 分子名称: | ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL, ADENOSINE MONOPHOSPHATE, ... | | 著者 | Yue, W.W, Kochan, G.T, Pilka, E.S, Bhatia, C, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Wikstrom, M, Bountra, C, Oppermann, U. | | 登録日 | 2008-07-31 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structural Snapshots for the Conformation- Dependent Catalysis by Human Medium-Chain Acyl- Coenzyme a Synthetase Acsm2A.
J.Mol.Biol., 388, 2009
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6PFH
 | | Crystal structure of TS-DHFR from Cryptosporidium hominis in complex with NADPH, FdUMP and 2-(2-(4-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl)benzamido)-4-cyanophenyl)acetic acid. | | 分子名称: | 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, Bifunctional dihydrofolate reductase-thymidylate synthase, METHOTREXATE, ... | | 著者 | Czyzyk, D.C, Valhondo, M, Jorgensen, W.L, Anderson, K.S. | | 登録日 | 2019-06-21 | | 公開日 | 2019-10-02 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | | 主引用文献 | Structure activity relationship towards design of cryptosporidium specific thymidylate synthase inhibitors.
Eur.J.Med.Chem., 183, 2019
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2N6G
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2VN2
 | | Crystal structure of the N-terminal domain of DnaD protein from Geobacillus kaustophilus HTA426 | | 分子名称: | CHROMOSOME REPLICATION INITIATION PROTEIN, MAGNESIUM ION | | 著者 | Huang, C.-Y, Chang, Y.-W, Chen, W.-T, Sun, Y.-J, Hsiao, C.-D. | | 登録日 | 2008-01-30 | | 公開日 | 2008-08-12 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structure of the N-Terminal Domain of Geobacillus Kaustophilus Hta426 Dnad Protein.
Biochem.Biophys.Res.Commun., 375, 2008
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1C10
 | | CRYSTAL STRUCTURE OF HEW LYSOZYME UNDER PRESSURE OF XENON (8 BAR) | | 分子名称: | CHLORIDE ION, PROTEIN (LYSOZYME), SODIUM ION, ... | | 著者 | Prange, T, Schiltz, M, Pernot, L, Colloc'h, N, Longhi, S, Bourguet, W, Fourme, R. | | 登録日 | 1999-07-16 | | 公開日 | 1999-07-22 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Exploring hydrophobic sites in proteins with xenon or krypton.
Proteins, 30, 1998
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3WA9
 | | The nucleosome containing human H2A.Z.1 | | 分子名称: | DNA (146-MER), Histone H2A.Z, Histone H2B type 1-J, ... | | 著者 | Horikoshi, N, Sato, K, Shimada, K, Arimura, Y, Osakabe, A, Tachiwana, H, Iwasaki, W, Kagawa, W, Harata, M, Kimura, H, Kurumizaka, H. | | 登録日 | 2013-04-30 | | 公開日 | 2013-12-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | | 主引用文献 | Structural polymorphism in the L1 loop regions of human H2A.Z.1 and H2A.Z.2
Acta Crystallogr.,Sect.D, 69, 2013
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5YDF
 | | Crystal structure of a disease-related gene, hCDC73(1-100) | | 分子名称: | Parafibromin | | 著者 | Sun, W, Kuang, X.L, Liu, Y.P, Tian, L.F, Yan, X.X, Xu, W.Q. | | 登録日 | 2017-09-13 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.399 Å) | | 主引用文献 | Crystal structure of the N-terminal domain of human CDC73 and its implications for the hyperparathyroidism-jaw tumor (HPT-JT) syndrome
Sci Rep, 7, 2017
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8AMG
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