6EYN

Structure of the 8D6 (anti-IgE) Fab

Summary for 6EYN

Entry DOI	10.2210/pdb6eyn/pdb
Descriptor	8D6 Fab light chain, 8D6 Fab heavy chain, DI(HYDROXYETHYL)ETHER, ... (6 entities in total)
Functional Keywords	immunoglobulin e, fab, antibody, immune system
Biological source	Homo sapiens More
Total number of polymer chains	6
Total formula weight	146048.54
Authors	Chen, J.B.,Ramadani, F.,Pang, M.O.Y.,Beavil, R.L.,Holdom, M.D.,Mitropoulou, A.N.,Beavil, A.J.,Gould, H.J.,Chang, T.W.,Sutton, B.J.,McDonnell, J.M.,Davies, A.M. (deposition date: 2017-11-13, release date: 2018-08-15, Last modification date: 2024-01-17)
Primary citation	Chen, J.B.,Ramadani, F.,Pang, M.O.Y.,Beavil, R.L.,Holdom, M.D.,Mitropoulou, A.N.,Beavil, A.J.,Gould, H.J.,Chang, T.W.,Sutton, B.J.,McDonnell, J.M.,Davies, A.M. Structural basis for selective inhibition of immunoglobulin E-receptor interactions by an anti-IgE antibody. Sci Rep, 8:11548-11548, 2018 Cited by PubMed: 30069035 DOI: 10.1038/s41598-018-29664-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation