6EYN

Structure of the 8D6 (anti-IgE) Fab

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue PEG L 301

Chain	Residue
C	SER60
L	GLU84
L	LYS173
L	ASP174
L	HOH417

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site_id	AC2
Number of Residues	3
Details	binding site for residue PEG L 302

Chain	Residue
L	SER160
L	GLY161
L	ASN162

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site_id	AC3
Number of Residues	5
Details	binding site for residue PEG L 303

Chain	Residue
L	ARG65
L	PHE66
L	GLU85
L	ASP86
L	HIS41

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site_id	AC4
Number of Residues	7
Details	binding site for residue EDO H 301

Chain	Residue
H	LEU147
H	VAL175
H	SER183
H	SER185
H	HOH409
L	THR182
L	HOH416

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site_id	AC5
Number of Residues	7
Details	binding site for residue EDO H 302

Chain	Residue
H	PRO132
H	SER133
H	ALA142
H	ALA143
H	HOH425
L	PHE120
L	ILE121

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site_id	AC6
Number of Residues	4
Details	binding site for residue EDO H 303

Chain	Residue
H	TRP33
H	TYR50
H	ASN52
H	HIS57

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site_id	AC7
Number of Residues	3
Details	binding site for residue EDO H 304

Chain	Residue
H	LYS63
H	PHE64
H	LYS67

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site_id	AC8
Number of Residues	3
Details	binding site for residue EDO H 305

Chain	Residue
D	SER25
D	GLY26
H	GLY140

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site_id	AC9
Number of Residues	4
Details	binding site for residue EDO B 301

Chain	Residue
B	LYS63
B	LYS67
B	HOH405
B	HOH406

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site_id	AD1
Number of Residues	3
Details	binding site for residue EDO B 302

Chain	Residue
B	TRP33
B	ASN52
B	HIS57

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site_id	AD2
Number of Residues	2
Details	binding site for residue EDO C 301

Chain	Residue
A	GLY61
C	GLU84

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site_id	AD3
Number of Residues	1
Details	binding site for residue EDO C 302

Chain	Residue
D	TRP105

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site_id	AD4
Number of Residues	1
Details	binding site for residue SO4 D 301

Chain	Residue
D	ARG102

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR200-HIS206
L	TYR196-HIS202

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