5O30
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5o30 by Molmil](/molmil-images/mine/5o30) | |
4KON
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4kon by Molmil](/molmil-images/mine/4kon) | The structure of hemagglutinin from avian-origin H7N9 influenza virus in complex with human receptor analog 6'SLNLN (NeuAcα2-6Galβ1-4GlcNAcβ1-3Galβ1-4Glc) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ... | 著者 | Shi, Y, Zhang, W, Wang, F, Qi, J, Song, H, Wu, Y, Gao, F, Zhang, Y, Fan, Z, Gong, W, Wang, D, Shu, Y, Wang, Y, Yan, J, Gao, G.F. | 登録日 | 2013-05-12 | 公開日 | 2013-11-06 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses. Science, 342, 2013
|
|
8SHJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8shj by Molmil](/molmil-images/mine/8shj) | Crystal structure of the WD-repeat domain of human WDR91 in complex with MR45279 | 分子名称: | N-[3-(4-chlorophenyl)oxetan-3-yl]-4-[(3S)-3-hydroxypyrrolidin-1-yl]benzamide, WD repeat-containing protein 91 | 著者 | Ahmad, H, Zeng, H, Dong, A, Li, Y, Hutchinson, A, Seitova, A, Xu, J, Feng, J.W, Brown, P.J, Ackloo, S, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | 登録日 | 2023-04-14 | 公開日 | 2023-07-05 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Discovery of a First-in-Class Small-Molecule Ligand for WDR91 Using DNA-Encoded Chemical Library Selection Followed by Machine Learning. J.Med.Chem., 66, 2023
|
|
8SU4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8su4 by Molmil](/molmil-images/mine/8su4) | F198S epi-Isozizaene Synthase: complex with 3 Mg2+, inorganic pyrophosphate, and benzyl triethyl ammonium cation | 分子名称: | Epi-isozizaene synthase, GLYCEROL, MAGNESIUM ION, ... | 著者 | Eaton, S.A, Christianson, D.W. | 登録日 | 2023-05-11 | 公開日 | 2023-07-26 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Reprogramming the Cyclization Cascade of epi -Isozizaene Synthase to Generate Alternative Terpene Products. Biochemistry, 62, 2023
|
|
8SU0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8su0 by Molmil](/molmil-images/mine/8su0) | |
4EGN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4egn by Molmil](/molmil-images/mine/4egn) | The X-ray crystal structure of CYP199A4 in complex with veratric acid | 分子名称: | 3,4-dimethoxybenzoic acid, CHLORIDE ION, Cytochrome P450, ... | 著者 | Zhou, W, Bell, S.G, Yang, W, Zhou, R.M, Tan, A.B.H, Wong, L.-L. | 登録日 | 2012-03-31 | 公開日 | 2013-02-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Investigation of the substrate range of CYP199A4: modification of the partition between hydroxylation and desaturation activities by substrate and protein engineering Chemistry, 18, 2012
|
|
8SU1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8su1 by Molmil](/molmil-images/mine/8su1) | |
8SU3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8su3 by Molmil](/molmil-images/mine/8su3) | F95S epi-Isozizaene Synthase: complex with 3 Mg2+, inorganic pyrophosphate, and benzyl triethyl ammonium cation | 分子名称: | Epi-isozizaene synthase, GLYCEROL, MAGNESIUM ION, ... | 著者 | Eaton, S.A, Christianson, D.W. | 登録日 | 2023-05-11 | 公開日 | 2023-07-26 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | 主引用文献 | Reprogramming the Cyclization Cascade of epi -Isozizaene Synthase to Generate Alternative Terpene Products. Biochemistry, 62, 2023
|
|
8SU5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8su5 by Molmil](/molmil-images/mine/8su5) | F198T epi-Isozizaene Synthase: complex with 3 Mg2+, inorganic pyrophosphate, and benzyl triethyl ammonium cation | 分子名称: | Epi-isozizaene synthase, GLYCEROL, MAGNESIUM ION, ... | 著者 | Eaton, S.A, Christianson, D.W. | 登録日 | 2023-05-11 | 公開日 | 2023-07-26 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Reprogramming the Cyclization Cascade of epi -Isozizaene Synthase to Generate Alternative Terpene Products. Biochemistry, 62, 2023
|
|
1Z36
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1z36 by Molmil](/molmil-images/mine/1z36) | Crystal structure of Trichomonas vaginalis purine nucleoside phosphorylase complexed with formycin A | 分子名称: | (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, purine nucleoside phosphorylase | 著者 | Zhang, Y, Wang, W.H, Wu, S.W, Wang, C.C, Ealick, S.E. | 登録日 | 2005-03-10 | 公開日 | 2005-03-29 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex. J.Biol.Chem., 280, 2005
|
|
8SU2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8su2 by Molmil](/molmil-images/mine/8su2) | |
8SPH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sph by Molmil](/molmil-images/mine/8sph) | Crystal structure of chimeric omicron RBD (strain XBB.1) complexed with human ACE2 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhang, W, Shi, K, Aihara, H, Li, F. | 登録日 | 2023-05-03 | 公開日 | 2023-08-02 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Structural evolution of SARS-CoV-2 omicron in human receptor recognition. J.Virol., 97, 2023
|
|
6K7Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6k7y by Molmil](/molmil-images/mine/6k7y) | Intact human mitochondrial calcium uniporter complex with MICU1/MICU2 subunits | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, CALCIUM ION, CARDIOLIPIN, ... | 著者 | Zhuo, W, Zhou, H, Yang, M. | 登録日 | 2019-06-10 | 公開日 | 2020-09-09 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure of intact human MCU supercomplex with the auxiliary MICU subunits. Protein Cell, 12, 2021
|
|
8SPI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8spi by Molmil](/molmil-images/mine/8spi) | Crystal structure of chimeric omicron RBD (strain XBB.1.5) complexed with human ACE2 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhang, W, Shi, K, Aihara, H, Li, F. | 登録日 | 2023-05-03 | 公開日 | 2023-08-02 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | 主引用文献 | Structural evolution of SARS-CoV-2 omicron in human receptor recognition. J.Virol., 97, 2023
|
|
4KOL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4kol by Molmil](/molmil-images/mine/4kol) | The structure of hemagglutinin from avian-origin H7N9 influenza virus | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2 | 著者 | Shi, Y, Zhang, W, Wang, F, Qi, J, Song, H, Wu, Y, Gao, F, Zhang, Y, Fan, Z, Gong, W, Wang, D, Shu, Y, Wang, Y, Yan, J, Gao, G.F. | 登録日 | 2013-05-12 | 公開日 | 2013-11-06 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.799 Å) | 主引用文献 | Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses. Science, 342, 2013
|
|
8IDE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ide by Molmil](/molmil-images/mine/8ide) | Structure of an ancient TsaD-TsaC-SUA5-TcdA modular enzyme (TsaN) | 分子名称: | MANGANESE (II) ION, N(6)-L-threonylcarbamoyladenine synthase | 著者 | Zhang, Z.L, Jin, M.Q, Yu, Z.J, Chen, W, Wang, X.L, Lei, D.S, Zhang, W.H. | 登録日 | 2023-02-13 | 公開日 | 2023-07-26 | 最終更新日 | 2023-09-20 | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | 主引用文献 | Structure-function analysis of an ancient TsaD-TsaC-SUA5-TcdA modular enzyme reveals a prototype of tRNA t6A and ct6A synthetases. Nucleic Acids Res., 51, 2023
|
|
5OC9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5oc9 by Molmil](/molmil-images/mine/5oc9) | Crystal Structure of human TMEM16K / Anoctamin 10 | 分子名称: | (2R)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, Anoctamin-10, CALCIUM ION | 著者 | Bushell, S.R, Pike, A.C.W, Chu, A, Tessitore, A, Rotty, B, Mukhopadhyay, S, Kupinska, K, Shrestha, L, Borkowska, O, Chalk, R, Burgess-Brown, N.A, Love, J, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2017-06-29 | 公開日 | 2018-07-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K. Nat Commun, 10, 2019
|
|
6NN9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nn9 by Molmil](/molmil-images/mine/6nn9) | REFINED ATOMIC STRUCTURES OF N9 SUBTYPE INFLUENZA VIRUS NEURAMINIDASE AND ESCAPE MUTANTS | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NEURAMINIDASE N9, ... | 著者 | Tulip, W.R, Varghese, J.N, Baker, A.T, Vandonkelaar, A, Laver, W.G, Webster, R.G, Colman, P.M. | 登録日 | 1991-03-28 | 公開日 | 1992-07-15 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Refined atomic structures of N9 subtype influenza virus neuraminidase and escape mutants. J.Mol.Biol., 221, 1991
|
|
7LUN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lun by Molmil](/molmil-images/mine/7lun) | Human PARP14 (ARTD8), catalytic fragment in complex with RBN011980 | 分子名称: | 7-(cyclopentylamino)-5-fluoro-2-{[(trans-4-hydroxycyclohexyl)sulfanyl]methyl}quinazolin-4(3H)-one, CHLORIDE ION, GLYCEROL, ... | 著者 | Dorsey, B.W, Swinger, K.K, Schenkel, L.B, Church, W.D, Perl, N.R, Vasbinder, M.M, Wigle, T.J, Kuntz, K.W. | 登録日 | 2021-02-22 | 公開日 | 2021-04-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | 主引用文献 | Targeted Degradation of PARP14 Using a Heterobifunctional Small Molecule. Chembiochem, 22, 2021
|
|
2NSW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2nsw by Molmil](/molmil-images/mine/2nsw) | |
4X36
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4x36 by Molmil](/molmil-images/mine/4x36) | Crystal structure of the autolysin LytA from Streptococcus pneumoniae TIGR4 | 分子名称: | Autolysin, CHOLINE ION, GLYCEROL, ... | 著者 | Cheng, W, Li, Q, Zhou, C.Z, Chen, Y.X. | 登録日 | 2014-11-28 | 公開日 | 2015-05-27 | 最終更新日 | 2015-06-24 | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | 主引用文献 | Full-length structure of the major autolysin LytA. Acta Crystallogr.,Sect.D, 71, 2015
|
|
5VEW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vew by Molmil](/molmil-images/mine/5vew) | Structure of the human GLP-1 receptor complex with PF-06372222 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Glucagon-like peptide 1 receptor,Endolysin chimera, N-{4-[(R)-(3,3-dimethylcyclobutyl)({6-[4-(trifluoromethyl)-1H-imidazol-1-yl]pyridin-3-yl}amino)methyl]benzene-1-carbonyl}-beta-alanine, ... | 著者 | Song, G, Yang, D, Wang, Y, Graaf, C.D, Zhou, Q, Jiang, S, Liu, K, Cai, X, Dai, A, Lin, G, Liu, D, Wu, F, Wu, Y, Zhao, S, Ye, L, Han, G.W, Lau, J, Wu, B, Hanson, M.A, Liu, Z.-J, Wang, M.-W, Stevens, R.C. | 登録日 | 2017-04-05 | 公開日 | 2017-05-24 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators. Nature, 546, 2017
|
|
6WLN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wln by Molmil](/molmil-images/mine/6wln) | hc16 ligase product models, 10.0 Angstrom resolution | 分子名称: | RNA (349-MER) | 著者 | Kappel, K, Zhang, K, Su, Z, Watkins, A.M, Kladwang, W, Li, S, Pintilie, G, Topkar, V.V, Rangan, R, Zheludev, I.N, Yesselman, J.D, Chiu, W, Das, R. | 登録日 | 2020-04-20 | 公開日 | 2020-07-08 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (10 Å) | 主引用文献 | Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures. Nat.Methods, 17, 2020
|
|
8SBD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sbd by Molmil](/molmil-images/mine/8sbd) | Cryo-EM structure of insulin amyloid-like fibril that is composed of two antiparallel protofilaments | 分子名称: | Insulin A chain, Insulin B chain | 著者 | Wang, L.W, Hall, C, Uchikawa, E, Chen, D.L, Choi, E, Zhang, X.W, Bai, X.C. | 登録日 | 2023-04-03 | 公開日 | 2023-08-30 | 最終更新日 | 2023-09-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis of insulin fibrillation. Sci Adv, 9, 2023
|
|
5WKC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wkc by Molmil](/molmil-images/mine/5wkc) | Saccharomyces cerevisiae acetohydroxyacid synthase in complex with the herbicide penoxsulam | 分子名称: | (3Z)-4-{[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]AMINO}-3-MERCAPTOPENT-3-EN-1-YL TRIHYDROGEN DIPHOSPHATE, 2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide, 2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-2-[(1~{S})-1-(dioxidanyl)-1-oxidanyl-ethyl]-4-methyl-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate, ... | 著者 | Guddat, W.L, Lonhienne, G.T. | 登録日 | 2017-07-25 | 公開日 | 2018-02-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.334 Å) | 主引用文献 | Structural insights into the mechanism of inhibition of AHAS by herbicides. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|