1TA6
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![BU of 1ta6 by Molmil](/molmil-images/mine/1ta6) | Crystal structure of thrombin in complex with compound 14b | 分子名称: | 1-[2-AMINO-2-CYCLOHEXYL-ACETYL]-PYRROLIDINE-3-CARBOXYLIC ACID 5-CHLORO-2-(2-ETHYLCARBAMOYL-ETHOXY)-BENZYLAMIDE, Hirudin, thrombin | 著者 | Tucker, T.J, Brady, S.F, Lumma, W.C, Lewis, S.D, Gardel, S.J, Naylor-Olsen, A.M, Yan, Y, Sisko, J.T, Stauffer, K.J, Lucas, B.Y, Lynch, J.J, Cook, J.J, Stranieri, M.T, Holahan, M.A, Lyle, E.A, Baskin, E.P, Chen, I.-W, Dancheck, K.B, Krueger, J.A, Cooper, C.M, Vacca, J.P. | 登録日 | 2004-05-19 | 公開日 | 2004-06-08 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Design and synthesis of a series of potent and orally bioavailable
noncovalent thrombin inhibitors that utilize nonbasic groups in the P1 position J.Med.Chem., 41, 1998
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1F8N
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1FD7
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![BU of 1fd7 by Molmil](/molmil-images/mine/1fd7) | HEAT-LABILE ENTEROTOXIN B-PENTAMER WITH BOUND LIGAND BMSC001 | 分子名称: | HEAT-LABILE ENTEROTOXIN B CHAIN, N-BENZYL-3-(ALPHA-D-GALACTOS-1-YL)-BENZAMIDE | 著者 | Fan, E, Merritt, E.A, Pickens, J, Ahn, M, Hol, W.G.J. | 登録日 | 2000-07-19 | 公開日 | 2000-08-10 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Exploration of the GM1 receptor-binding site of heat-labile enterotoxin and cholera toxin by phenyl-ring-containing galactose derivatives. Acta Crystallogr.,Sect.D, 57, 2001
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1FEH
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![BU of 1feh by Molmil](/molmil-images/mine/1feh) | FE-ONLY HYDROGENASE FROM CLOSTRIDIUM PASTEURIANUM | 分子名称: | 2 IRON/2 SULFUR/5 CARBONYL/2 WATER INORGANIC CLUSTER, FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER, ... | 著者 | Peters, J.W, Lanzilotta, W.N, Lemon, B.J, Seefeldt, L.C. | 登録日 | 1998-10-28 | 公開日 | 1999-01-13 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | X-ray crystal structure of the Fe-only hydrogenase (CpI) from Clostridium pasteurianum to 1.8 angstrom resolution. Science, 282, 1998
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6RJN
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![BU of 6rjn by Molmil](/molmil-images/mine/6rjn) | Crystal structure of a Fungal Catalase at 2.3 Angstroms | 分子名称: | CHLORIDE ION, Catalase, DI(HYDROXYETHYL)ETHER, ... | 著者 | Gomez, S, Navas-Yuste, S, Payne, A.M, Rivera, W, Lopez-Estepa, M, Brangbour, C, Fulla, D, Juanhuix, J, Fernandez, F.J, Vega, M.C. | 登録日 | 2019-04-28 | 公開日 | 2020-03-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.295 Å) | 主引用文献 | Peroxisomal catalases from the yeasts Pichia pastoris and Kluyveromyces lactis as models for oxidative damage in higher eukaryotes. Free Radic. Biol. Med., 141, 2019
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6XJ5
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6U7Y
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![BU of 6u7y by Molmil](/molmil-images/mine/6u7y) | RNA hairpin structure containing one TNA nucleotide as template | 分子名称: | CYTIDINE-5'-MONOPHOSPHATE, RNA (5'-R(*CP*UP*AP*UP*GP*CP*CP*UP*GP*CP*UP*G)-3'), RNA (5'-R(*CP*UP*GP*CP*UP*GP*GP*CP*UP*AP*AP*GP*GP*(TG)P*CP*CP*GP*AP*AP*AP*GP*G)-3') | 著者 | Szostak, J.W, Zhang, W. | 登録日 | 2019-09-03 | 公開日 | 2020-12-09 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structural interpretation of the effects of threo-nucleotides on nonenzymatic template-directed polymerization. Nucleic Acids Res., 49, 2021
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1FK3
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![BU of 1fk3 by Molmil](/molmil-images/mine/1fk3) | STRUCTURAL BASIS OF NON-SPECIFIC LIPID BINDING IN MAIZE LIPID-TRANSFER PROTEIN COMPLEXES WITH PALMITOLEIC ACID REVEALED BY HIGH-RESOLUTION X-RAY CRYSTALLOGRAPHY | 分子名称: | FORMIC ACID, NONSPECIFIC LIPID-TRANSFER PROTEIN, PALMITOLEIC ACID | 著者 | Han, G.W, Lee, J.Y, Song, H.K, Shin, D.H, Suh, S.W. | 登録日 | 2000-08-09 | 公開日 | 2001-06-06 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis of non-specific lipid binding in maize lipid-transfer protein complexes revealed by high-resolution X-ray crystallography. J.Mol.Biol., 308, 2001
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1T8F
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![BU of 1t8f by Molmil](/molmil-images/mine/1t8f) | Crystal structure of phage T4 lysozyme mutant R14A/K16A/I17A/K19A/T21A/E22A/C54T/C97A | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme | 著者 | He, M.M, Wood, Z.A, Baase, W.A, Xiao, H, Matthews, B.W. | 登録日 | 2004-05-12 | 公開日 | 2004-10-19 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Alanine-scanning mutagenesis of the beta-sheet region of phage T4 lysozyme suggests that tertiary context has a dominant effect on beta-sheet formation. Protein Sci., 13, 2004
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1FSB
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![BU of 1fsb by Molmil](/molmil-images/mine/1fsb) | STRUCTURE OF THE EGF DOMAIN OF P-SELECTIN, NMR, 19 STRUCTURES | 分子名称: | P-SELECTIN | 著者 | Freedman, S.J, Sanford, D.G, Bachovchin, W.W, Furie, B.C, Baleja, J.D, Furie, B. | 登録日 | 1996-03-25 | 公開日 | 1997-04-01 | 最終更新日 | 2017-11-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and function of the epidermal growth factor domain of P-selectin. Biochemistry, 35, 1996
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2MWI
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7ADQ
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![BU of 7adq by Molmil](/molmil-images/mine/7adq) | Serial Laue crystallography structure of dehaloperoxidase B from Amphitrite ornata | 分子名称: | Dehaloperoxidase B, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | 著者 | Moreno-Chicano, T.M, Ebrahim, A.E, Srajer, V, Henning, R.W, Doak, B.C, Trebbin, M, Monteiro, D.C.F, Hough, M.A. | 登録日 | 2020-09-15 | 公開日 | 2021-11-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Complementarity of neutron, XFEL and synchrotron crystallography for defining the structures of metalloenzymes at room temperature. Iucrj, 9, 2022
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1FGQ
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6EF4
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![BU of 6ef4 by Molmil](/molmil-images/mine/6ef4) | Crystal structure of mouse PP2A Aalpha P179R mutant | 分子名称: | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform | 著者 | Wang, Z, Shen, G, Xu, W. | 登録日 | 2018-08-16 | 公開日 | 2019-06-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | The Highly Recurrent PP2A A alpha-Subunit Mutation P179R Alters Protein Structure and Impairs PP2A Enzyme Function to Promote Endometrial Tumorigenesis. Cancer Res., 79, 2019
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7AEB
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![BU of 7aeb by Molmil](/molmil-images/mine/7aeb) | Cryo-EM structure of an extracellular contractile injection system in marine bacterium Algoriphagus machipongonensis, the baseplate complex in extended state applied 6-fold symmetry. | 分子名称: | Baseplate_J domain-containing protein, LysM domain-containing protein, Phage tail protein, ... | 著者 | Xu, J, Ericson, C, Feldmueller, M, Lien, Y.W, Pilhofer, M. | 登録日 | 2020-09-17 | 公開日 | 2022-02-16 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Identification and structure of an extracellular contractile injection system from the marine bacterium Algoriphagus machipongonensis. Nat Microbiol, 7, 2022
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6EQJ
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![BU of 6eqj by Molmil](/molmil-images/mine/6eqj) | Crystal Structure of Human Glycogenin-1 (GYG1) Tyr195pIPhe mutant, apo form | 分子名称: | 1,2-ETHANEDIOL, Glycogenin-1 | 著者 | Bailey, H.J, Kopec, J, Bilyard, M.K, Bezerra, G.A, Seo Lee, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Davis, B.G, Yue, W.W. | 登録日 | 2017-10-13 | 公開日 | 2017-12-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Palladium-mediated enzyme activation suggests multiphase initiation of glycogenesis. Nature, 563, 2018
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7AEF
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![BU of 7aef by Molmil](/molmil-images/mine/7aef) | Cryo-EM structure of an extracellular contractile injection system in marine bacterium Algoriphagus machipongonensis, the baseplate complex in extended state applied 3-fold symmetry. | 分子名称: | Baseplate_J domain-containing protein, LysM domain-containing protein, Phage tail protein, ... | 著者 | Xu, J, Ericson, C, Feldmueller, M, Lien, Y.W, Pilhofer, M. | 登録日 | 2020-09-17 | 公開日 | 2022-02-23 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Identification and structure of an extracellular contractile injection system from the marine bacterium Algoriphagus machipongonensis. Nat Microbiol, 7, 2022
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1TBD
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![BU of 1tbd by Molmil](/molmil-images/mine/1tbd) | SOLUTION STRUCTURE OF THE ORIGIN DNA BINDING DOMAIN OF SV40 T-ANTIGEN, NMR, MINIMIZED AVERAGE STRUCTURE | 分子名称: | SV40 T-ANTIGEN | 著者 | Luo, X, Sanford, D.G, Bullock, P.A, Bachovchin, W.W. | 登録日 | 1996-11-04 | 公開日 | 1997-03-12 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the origin DNA-binding domain of SV40 T-antigen. Nat.Struct.Biol., 3, 1996
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6XEV
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![BU of 6xev by Molmil](/molmil-images/mine/6xev) | CryoEM structure of GIRK2-PIP2/CHS - G protein-gated inwardly rectifying potassium channel GIRK2 with modulators cholesteryl hemisuccinate and PIP2 | 分子名称: | CHOLESTEROL HEMISUCCINATE, G protein-activated inward rectifier potassium channel 2, POTASSIUM ION, ... | 著者 | Mathiharan, Y.K, Glaaser, I.W, Skiniotis, G, Slesinger, P.A. | 登録日 | 2020-06-14 | 公開日 | 2021-09-01 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural insights into GIRK2 channel modulation by cholesterol and PIP2 Cell Rep, 36, 2021
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1FBZ
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![BU of 1fbz by Molmil](/molmil-images/mine/1fbz) | Structure-based design of a novel, osteoclast-selective, nonpeptide Src SH2 inhibitor with in vivo anti-resorptive activity | 分子名称: | PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK, {4-[2-ACETYLAMINO-2-(3-CARBAMOYL-2-CYCLOHEXYLMETHOXY-6,7,8,9-TETRAHYDRO-5H-BENZOCYCLOHEPTEN-5YLCARBAMOYL)-ETHYL]-2-PHOSPHONO-PHENYL}-PHOSPHONIC ACID | 著者 | Shakespeare, W, Yang, M, Bohacek, R, Cerasoli, F, Stebbis, K, Sundaramoorthi, R, Vu, C, Pradeepan, S, Metcalf, C, Haraldson, C, Merry, T, Dalgarno, D, Narula, S, Hatada, M, Lu, X, Van Schravendijk, M.R, Adams, S, Violette, S, Smith, J, Guan, W, Bartlett, C, Herson, J, Iuliucci, J, Weigele, M, Sawyer, T. | 登録日 | 2000-07-17 | 公開日 | 2000-08-23 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure-based design of an osteoclast-selective, nonpeptide src homology 2 inhibitor with in vivo antiresorptive activity. Proc.Natl.Acad.Sci.Usa, 97, 2000
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1FGT
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4C45
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![BU of 4c45 by Molmil](/molmil-images/mine/4c45) | Crystal structure of human pterin-4-alpha-carbinolamine dehydratase 2 (PCBD2) | 分子名称: | 1,2-ETHANEDIOL, PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE 2 | 著者 | Kopec, J, Kiyani, W, Vollmar, M, Shrestha, L, Canning, P, von Delft, F, Burgess-Brown, N, Bountra, C, Arrowsmith, C.H, Edwards, A, Yue, W.W. | 登録日 | 2013-08-30 | 公開日 | 2013-09-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Crystal Structure of Human Pterin-4-Alpha- Carbinolamine Dehydratase 2 (Pcbd2) To be Published
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1TDC
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![BU of 1tdc by Molmil](/molmil-images/mine/1tdc) | STRUCTURES OF THYMIDYLATE SYNTHASE WITH A C-TERMINAL DELETION: ROLE OF THE C-TERMINUS IN ALIGNMENT OF D/UMP AND CH2H4FOLATE | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE | 著者 | Perry, K.M, Carreras, C.W, Chang, L.C, Santi, D.V, Stroud, R.M. | 登録日 | 1993-02-15 | 公開日 | 1993-07-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structures of thymidylate synthase with a C-terminal deletion: role of the C-terminus in alignment of 2'-deoxyuridine 5'-monophosphate and 5,10-methylenetetrahydrofolate. Biochemistry, 32, 1993
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1FK0
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![BU of 1fk0 by Molmil](/molmil-images/mine/1fk0) | STRUCTURAL BASIS OF NON-SPECIFIC LIPID BINDING IN MAIZE LIPID-TRANSFER PROTEIN COMPLEXES WITH CAPRIC ACID REVEALED BY HIGH-RESOLUTION X-RAY CRYSTALLOGRAPHY | 分子名称: | DECANOIC ACID, FORMIC ACID, NONSPECIFIC LIPID-TRANSFER PROTEIN | 著者 | Han, G.W, Lee, J.Y, Song, H.K, Shin, D.H, Suh, S.W. | 登録日 | 2000-08-08 | 公開日 | 2001-06-06 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis of non-specific lipid binding in maize lipid-transfer protein complexes revealed by high-resolution X-ray crystallography. J.Mol.Biol., 308, 2001
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4CCZ
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![BU of 4ccz by Molmil](/molmil-images/mine/4ccz) | Crystal structure of human 5-methyltetrahydrofolate-homocysteine methyltransferase, the homocysteine and folate binding domains | 分子名称: | (6S)-5,6,7,8-TETRAHYDROFOLATE, METHIONINE SYNTHASE | 著者 | Vollmar, M, Kiyani, W, Krojer, T, Goubin, S, Burgess-Brown, N, von Delft, F, Oppermann, U, Edwards, A, Arrowsmith, C, Bountra, C, Yue, W.W. | 登録日 | 2013-10-29 | 公開日 | 2013-11-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal Structure of Human 5-Methyltetrahydrofolate-Homocysteine Methyltransferase, the Homocysteine and Folate Binding Domains To be Published
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