4R02
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![BU of 4r02 by Molmil](/molmil-images/mine/4r02) | yCP in complex with BSc4999 (alpha-Keto Phenylamide) | 分子名称: | MAGNESIUM ION, N-[(benzyloxy)carbonyl]-L-leucyl-N-{(2S,3S)-1-[(2,4-dimethylphenyl)amino]-2-hydroxy-5-methyl-1-oxohexan-3-yl}-L-leucinamide, Probable proteasome subunit alpha type-7, ... | 著者 | Voss, C, Scholz, C, Knorr, S, Beck, P, Stein, M, Zall, A, Kuckelkorn, U, Kloetzel, P.-M, Groll, M, Hamacher, K, Schmidt, B. | 登録日 | 2014-07-29 | 公開日 | 2014-08-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | alpha-Keto Phenylamides as P1'-Extended Proteasome Inhibitors. Chemmedchem, 9, 2014
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4F5A
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![BU of 4f5a by Molmil](/molmil-images/mine/4f5a) | Triple mutant Src SH2 domain bound to phosphate ion | 分子名称: | PHOSPHATE ION, Proto-oncogene tyrosine-protein kinase Src | 著者 | Kaneko, T, Huang, H, Cao, X, Li, C, Voss, C, Sidhu, S.S, Li, S.S. | 登録日 | 2012-05-12 | 公開日 | 2012-10-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Superbinder SH2 Domains Act as Antagonists of Cell Signaling. Sci.Signal., 5, 2012
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4F5B
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![BU of 4f5b by Molmil](/molmil-images/mine/4f5b) | Triple mutant Src SH2 domain bound to phosphotyrosine | 分子名称: | O-PHOSPHOTYROSINE, Proto-oncogene tyrosine-protein kinase Src | 著者 | Kaneko, T, Huang, H, Cao, X, Li, C, Voss, C, Sidhu, S.S, Li, S.S. | 登録日 | 2012-05-12 | 公開日 | 2012-10-03 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Superbinder SH2 Domains Act as Antagonists of Cell Signaling. Sci.Signal., 5, 2012
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3MAZ
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![BU of 3maz by Molmil](/molmil-images/mine/3maz) | Crystal Structure of the Human BRDG1/STAP-1 SH2 Domain in Complex with the NTAL pTyr136 Peptide | 分子名称: | CheD family protein, MALONATE ION, Signal-transducing adaptor protein 1 | 著者 | Kaneko, T, Huang, H, Zhao, B, Li, L, Liu, H, Voss, C.K, Wu, C, Schiller, M.R, Li, S.S. | 登録日 | 2010-03-24 | 公開日 | 2010-05-12 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Loops govern SH2 domain specificity by controlling access to binding pockets. Sci.Signal., 3, 2010
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4NO6
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![BU of 4no6 by Molmil](/molmil-images/mine/4no6) | yCP in complex with Z-Leu-Leu-Leu-vinylsulfone | 分子名称: | MAGNESIUM ION, N-[(benzyloxy)carbonyl]-L-leucyl-N-[(3S)-5-methyl-1-(methylsulfonyl)hexan-3-yl]-L-leucinamide, Probable proteasome subunit alpha type-7, ... | 著者 | Stein, M.L, Cui, H, Beck, P, Dubiella, C, Voss, C, Krueger, A, Schmidt, B, Groll, M. | 登録日 | 2013-11-19 | 公開日 | 2014-02-12 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Systematic Comparison of Peptidic Proteasome Inhibitors Highlights the alpha-Ketoamide Electrophile as an Auspicious Reversible Lead Motif. Angew.Chem.Int.Ed.Engl., 53, 2014
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4NNN
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![BU of 4nnn by Molmil](/molmil-images/mine/4nnn) | yCP in complex with MG132 | 分子名称: | MAGNESIUM ION, N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S)-1-hydroxy-4-methylpentan-2-yl]-L-leucinamide, Probable proteasome subunit alpha type-7, ... | 著者 | Stein, M.L, Cui, H, Beck, P, Dubiella, C, Voss, C, Krueger, A, Schmidt, B, Groll, M. | 登録日 | 2013-11-18 | 公開日 | 2014-02-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Systematic Comparison of Peptidic Proteasome Inhibitors Highlights the alpha-Ketoamide Electrophile as an Auspicious Reversible Lead Motif. Angew.Chem.Int.Ed.Engl., 53, 2014
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4NO9
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![BU of 4no9 by Molmil](/molmil-images/mine/4no9) | yCP in complex with Z-Leu-Leu-Leu-epoxyketone | 分子名称: | MAGNESIUM ION, N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2R,3S,4S)-1,3-dihydroxy-2,6-dimethylheptan-4-yl]-L-leucinamide, N-[(benzyloxy)carbonyl]-L-leucyl-N-{(1R,2S)-1-hydroxy-4-methyl-1-[(2R)-2-methyloxiran-2-yl]pentan-2-yl}-L-leucinamide, ... | 著者 | Stein, M.L, Cui, H, Beck, P, Dubiella, C, Voss, C, Krueger, A, Schmidt, B, Groll, M. | 登録日 | 2013-11-19 | 公開日 | 2014-02-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Systematic Comparison of Peptidic Proteasome Inhibitors Highlights the alpha-Ketoamide Electrophile as an Auspicious Reversible Lead Motif. Angew.Chem.Int.Ed.Engl., 53, 2014
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4F59
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![BU of 4f59 by Molmil](/molmil-images/mine/4f59) | Triple mutant Src SH2 domain | 分子名称: | Proto-oncogene tyrosine-protein kinase Src | 著者 | Kaneko, T, Huang, H, Cao, X, Li, C, Voss, C, Sidhu, S.S, Li, S.S. | 登録日 | 2012-05-12 | 公開日 | 2012-10-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Superbinder SH2 Domains Act as Antagonists of Cell Signaling. Sci.Signal., 5, 2012
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4NNW
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![BU of 4nnw by Molmil](/molmil-images/mine/4nnw) | yCP in complex with Z-Leu-Leu-Leu-ketoaldehyde | 分子名称: | MAGNESIUM ION, N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2R,3S)-1,2-dihydroxy-5-methylhexan-3-yl]-L-leucinamide, Probable proteasome subunit alpha type-7, ... | 著者 | Stein, M.L, Cui, H, Beck, P, Dubiella, C, Voss, C, Krueger, A, Schmidt, B, Groll, M. | 登録日 | 2013-11-19 | 公開日 | 2014-02-12 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Systematic Comparison of Peptidic Proteasome Inhibitors Highlights the alpha-Ketoamide Electrophile as an Auspicious Reversible Lead Motif. Angew.Chem.Int.Ed.Engl., 53, 2014
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4NO1
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![BU of 4no1 by Molmil](/molmil-images/mine/4no1) | yCP in complex with Z-Leu-Leu-Leu-B(OH)2 | 分子名称: | MAGNESIUM ION, N-[(benzyloxy)carbonyl]-L-leucyl-N-[(1R)-1-(dihydroxyboranyl)-3-methylbutyl]-L-leucinamide, Probable proteasome subunit alpha type-7, ... | 著者 | Stein, M.L, Cui, H, Beck, P, Dubiella, C, Voss, C, Krueger, A, Schmidt, B, Groll, M. | 登録日 | 2013-11-19 | 公開日 | 2014-02-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Systematic Comparison of Peptidic Proteasome Inhibitors Highlights the alpha-Ketoamide Electrophile as an Auspicious Reversible Lead Motif. Angew.Chem.Int.Ed.Engl., 53, 2014
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4NO8
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![BU of 4no8 by Molmil](/molmil-images/mine/4no8) | yCP in complex with Z-Leu-Leu-Leu-ketoamide | 分子名称: | MAGNESIUM ION, N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S,3S)-2-hydroxy-5-methyl-1-oxo-1-(phenylamino)hexan-3-yl]-L-leucinamide, Probable proteasome subunit alpha type-7, ... | 著者 | Stein, M.L, Cui, H, Beck, P, Dubiella, C, Voss, C, Krueger, A, Schmidt, B, Groll, M. | 登録日 | 2013-11-19 | 公開日 | 2014-02-12 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Systematic Comparison of Peptidic Proteasome Inhibitors Highlights the alpha-Ketoamide Electrophile as an Auspicious Reversible Lead Motif. Angew.Chem.Int.Ed.Engl., 53, 2014
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6RM3
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![BU of 6rm3 by Molmil](/molmil-images/mine/6rm3) | Evolutionary compaction and adaptation visualized by the structure of the dormant microsporidian ribosome | 分子名称: | 16S rRNA, 23S rRNA, 5S rRNA, ... | 著者 | Barandun, J, Hunziker, M, Vossbrinck, C.R, Klinge, S. | 登録日 | 2019-05-05 | 公開日 | 2019-07-10 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Evolutionary compaction and adaptation visualized by the structure of the dormant microsporidian ribosome. Nat Microbiol, 4, 2019
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6ZU5
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![BU of 6zu5 by Molmil](/molmil-images/mine/6zu5) | Structure of the Paranosema locustae ribosome in complex with Lso2 | 分子名称: | 18S rRNA, 25S rRNA, 5S rRNA, ... | 著者 | Ehrenbolger, K, Jespersen, N, Sharma, H, Sokolova, Y.Y, Tokarev, Y.S, Vossbrinck, C.R, Barandun, J. | 登録日 | 2020-07-21 | 公開日 | 2020-11-04 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Differences in structure and hibernation mechanism highlight diversification of the microsporidian ribosome. Plos Biol., 18, 2020
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8ADN
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![BU of 8adn by Molmil](/molmil-images/mine/8adn) | Vairimorpha necatrix 20S proteasome from spores | 分子名称: | Proteasome Inhibitor 31-Like, Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, ... | 著者 | Jespersen, N, Ehrenbolger, K, Winiger, R, Svedberg, D, Vossbrinck, C.R, Barandun, J. | 登録日 | 2022-07-08 | 公開日 | 2022-11-23 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | Structure of the reduced microsporidian proteasome bound by PI31-like peptides in dormant spores. Nat Commun, 13, 2022
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