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PDB: 149 件
6B26
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Crystal structure of human STAC2 Tandem SH3 Domains (296-411)
分子名称: SH3 and cysteine-rich domain-containing protein 2
著者Wong King Yuen, S.M, Van Petegem, F.
登録日2017-09-19
公開日2017-10-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structural insights into binding of STAC proteins to voltage-gated calcium channels.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6B25
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Crystal structure of human STAC1 Tandem SH3 Domains (288-402)
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SH3 and cysteine-rich domain-containing protein
著者Wong King Yuen, S.M, Van Petegem, F.
登録日2017-09-19
公開日2017-10-25
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structural insights into binding of STAC proteins to voltage-gated calcium channels.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6DAF
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2.4 Angstrom crystal structure of the F141L Ca/CaM:CaV1.2 IQ domain complex
分子名称: CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C
著者Wang, K, Van Petegem, F.
登録日2018-05-01
公開日2018-10-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DLG
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Crystal structure of a SHIP1 surface entropy reduction mutant
分子名称: ISOPROPYL ALCOHOL, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1
著者Gardill, B.R, Cheung, S.T, Mui, A.L, Van Petegem, F.
登録日2018-06-01
公開日2019-06-05
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.499 Å)
主引用文献Interleukin-10 and Small Molecule SHIP1 Allosteric Regulators Trigger Anti-Inflammatory Effects Through SHIP1/STAT3 Complexes
Biorxiv, 2020
6DAE
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2.0 Angstrom crystal structure of the D95V Ca/CaM:CaV1.2 IQ domain complex
分子名称: CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C
著者Wang, K, Lu, J, Van Petegem, F.
登録日2018-05-01
公開日2018-10-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DAD
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1.65 Angstrom crystal structure of the N97I Ca/CaM:CaV1.2 IQ domain complex
分子名称: CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C
著者Wang, K, Van Petegem, F.
登録日2018-05-01
公開日2018-10-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DAH
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2.5 Angstrom crystal structure of the N97S CaM mutant
分子名称: CALCIUM ION, Calmodulin-1
著者Wang, K, Van Petegem, F.
登録日2018-05-01
公開日2018-10-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.502 Å)
主引用文献Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3OXQ
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BU of 3oxq by Molmil
Crystal Structure of Ca2+/CaM-CaV1.2 pre-IQ/IQ domain complex
分子名称: CALCIUM ION, Calmodulin, Voltage-dependent L-type calcium channel subunit alpha-1C
著者Kim, E.Y, Rumpf, C.H, Van Petegem, F, Arant, R, Findeisen, F, Cooley, E.S, Isacoff, E.Y, Minor, D.L.
登録日2010-09-21
公開日2010-11-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Multiple C-terminal tail Ca(2+)/CaMs regulate Ca(V)1.2 function but do not mediate channel dimerization.
Embo J., 29, 2010
3QR5
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Structure of the first domain of a cardiac Ryanodine Receptor mutant with exon 3 deleted
分子名称: Cardiac Ca2+ release channel
著者Lobo, P.A, Van Petegem, F.
登録日2011-02-17
公開日2011-06-08
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The deletion of exon 3 in the cardiac ryanodine receptor is rescued by beta strand switching.
Structure, 19, 2011
4KEI
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Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant P164S
分子名称: Ryanodine receptor 2
著者Kimlicka, L, Van Petegem, F.
登録日2013-04-25
公開日2013-09-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.406 Å)
主引用文献Type 2 Ryanodine Receptor Domain A Contains a Unique and Dynamic alpha-Helix That Transitions to a beta-Strand in a Mutant Linked with a Heritable Cardiomyopathy.
J.Mol.Biol., 425, 2013
4KEK
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Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant R176Q
分子名称: Ryanodine receptor 2, SULFATE ION
著者Kimlicka, L, Van Petegem, F.
登録日2013-04-25
公開日2013-09-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.146 Å)
主引用文献Type 2 Ryanodine Receptor Domain A Contains a Unique and Dynamic alpha-Helix That Transitions to a beta-Strand in a Mutant Linked with a Heritable Cardiomyopathy.
J.Mol.Biol., 425, 2013
3ILA
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Crystal structure of rabbit ryanodine receptor 1 N-terminal domain (9-205)
分子名称: Ryanodine receptor 1
著者Lobo, P.A, Van Petegem, F.
登録日2009-08-06
公開日2009-11-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structures of the N-terminal domains of cardiac and skeletal muscle ryanodine receptors: insights into disease mutations.
Structure, 17, 2009
4KEJ
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Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant R169Q
分子名称: Ryanodine receptor 2
著者Kimlicka, L, Van Petegem, F.
登録日2013-04-25
公開日2013-09-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.553 Å)
主引用文献Type 2 Ryanodine Receptor Domain A Contains a Unique and Dynamic alpha-Helix That Transitions to a beta-Strand in a Mutant Linked with a Heritable Cardiomyopathy.
J.Mol.Biol., 425, 2013
4L4I
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Crystal structure of mouse Ryanodine Receptor isoform 2 (RyR2) 1-547 disease mutant R420Q
分子名称: GLYCEROL, Ryanodine receptor 2
著者Kimlicka, L, Van Petegem, F.
登録日2013-06-07
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of ryanodine receptor disease mutant
To be Published
4L4H
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Crystal structure of mouse Ryanodine Receptor isoform 2 (RyR2) 1-547
分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Ryanodine receptor 2, ...
著者Kimlicka, L, Tung, C.C, Van Petegem, F.
登録日2013-06-07
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a ryanodine receptor domain
To be Published
4P9J
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Crystal Structure of rabbit Ryanodine Receptor 1 SPRY2 Domain (1070-1246)
分子名称: Ryanodine receptor 1
著者Lau, K, Van Petegem, F.
登録日2014-04-04
公開日2014-11-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.
Nat Commun, 5, 2014
4MZ2
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BU of 4mz2 by Molmil
Crystal structure of the voltage-gated sodium channel beta 4 subunit extracellular domain
分子名称: Sodium channel subunit beta-4
著者Das, S, Van Petegem, F.
登録日2013-09-28
公開日2013-12-04
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.722 Å)
主引用文献Crystallographic insights into sodium-channel modulation by the beta 4 subunit.
Proc.Natl.Acad.Sci.USA, 110, 2013
4P9I
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Crystal Structure of mouse Ryanodine Receptor 2 SPRY2 Domain (1080-1253)
分子名称: Ryanodine receptor 2
著者Lau, K, Van Petegem, F.
登録日2014-04-04
公開日2014-11-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.3401 Å)
主引用文献Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.
Nat Commun, 5, 2014
4P9L
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Crystal Structure of mouse Ryanodine Receptor 2 SPRY2 Domain (1080-1253) disease mutant A1107M
分子名称: Ryanodine receptor 2
著者Lau, K, Van Petegem, F.
登録日2014-04-04
公開日2014-11-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.4361 Å)
主引用文献Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.
Nat Commun, 5, 2014
4I6I
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Crystal structure of rabbit ryanodine receptor 1 (residues 1-559) disease mutant R45C
分子名称: Ryanodine receptor 1
著者Kimlicka, L, Van Petegem, F.
登録日2012-11-29
公開日2013-02-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Disease mutations in the ryanodine receptor N-terminal region couple to a mobile intersubunit interface.
Nat Commun, 4, 2013
3DVE
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BU of 3dve by Molmil
Crystal Structure of Ca2+/CaM-CaV2.2 IQ domain complex
分子名称: CALCIUM ION, Calmodulin, NICKEL (II) ION, ...
著者Kim, E.Y, Rumpf, C.H, Fujiwara, Y, Cooley, E.S, Van Petegem, F, Minor, D.L.
登録日2008-07-18
公開日2008-11-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structures of Ca(V)2 Ca(2+)/CaM-IQ Domain Complexes Reveal Binding Modes that Underlie Calcium-Dependent Inactivation and Facilitation.
Structure, 16, 2008
3DVM
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BU of 3dvm by Molmil
Crystal Structure of Ca2+/CaM-CaV2.1 IQ domain complex
分子名称: CALCIUM ION, Calmodulin, Voltage-dependent P/Q-type calcium channel subunit alpha-1A
著者Kim, E.Y, Rumpf, C.H, Fujiwara, Y, Cooley, E.S, Van Petegem, F, Minor, D.L.
登録日2008-07-18
公開日2008-11-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of Ca(V)2 Ca(2+)/CaM-IQ Domain Complexes Reveal Binding Modes that Underlie Calcium-Dependent Inactivation and Facilitation.
Structure, 16, 2008
3DVJ
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Crystal Structure of Ca2+/CaM-CaV2.2 IQ domain (without cloning artifact, HM to TV) complex
分子名称: CALCIUM ION, Calmodulin, Voltage-dependent N-type calcium channel subunit alpha-1B
著者Kim, E.Y, Rumpf, C.H, Fujiwara, Y, Cooley, E.S, Van Petegem, F, Minor, D.L.
登録日2008-07-18
公開日2008-11-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of Ca(V)2 Ca(2+)/CaM-IQ Domain Complexes Reveal Binding Modes that Underlie Calcium-Dependent Inactivation and Facilitation.
Structure, 16, 2008
3DVK
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Crystal Structure of Ca2+/CaM-CaV2.3 IQ domain complex
分子名称: CALCIUM ION, Calmodulin, Voltage-dependent R-type calcium channel subunit alpha-1E
著者Kim, E.Y, Rumpf, C.H, Fujiwara, Y, Cooley, E.S, Van Petegem, F, Minor, D.L.
登録日2008-07-18
公開日2008-11-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of Ca(V)2 Ca(2+)/CaM-IQ Domain Complexes Reveal Binding Modes that Underlie Calcium-Dependent Inactivation and Facilitation.
Structure, 16, 2008
3FYQ
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Structure of Drosophila melanogaster talin IBS2 domain (residues 1981-2168)
分子名称: CG6831-PA (Talin)
著者Cheung, T.Y.S, Fairchild, M.J, Zarivach, R, Tanentzapf, G, Van Petegem, F.
登録日2009-01-22
公開日2009-02-03
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of the talin integrin binding domain 2.
J.Mol.Biol., 387, 2009

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