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PDB: 123 件

4IJ1
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BU of 4ij1 by Molmil
Bianthranilate-like analogue bound to anthranilate phosphoribosyltransferase (AnPRT; trpD) in absence of substrates.
分子名称: 2,2'-iminodibenzoic acid, Anthranilate phosphoribosyltransferase, GLYCEROL, ...
著者Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2012-12-20
公開日2013-12-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Repurposing the Chemical Scaffold of the Anti-Arthritic Drug Lobenzarit to Target Tryptophan Biosynthesis in Mycobacterium tuberculosis.
Chembiochem, 15, 2014
4YI7
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BU of 4yi7 by Molmil
Anthranilate bound at active site of anthranilate phosphoribosyl transferase from Acinetobacter (AnPRT; TrpD)
分子名称: 2-AMINOBENZOIC ACID, Anthranilate phosphoribosyltransferase
著者Evans, G.L, Newton, M.S, Norris, G.E, Patrick, W.M.
登録日2015-02-28
公開日2015-09-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.853 Å)
主引用文献Substrate inhibition of protein in tryptophan biosynthesis pathway redirects flux to aromatic catabolism in Acinetobacter baylyi ADP1.
To Be Published
6ZET
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BU of 6zet by Molmil
Crystal structure of proteinase K nanocrystals by electron diffraction with a 20 micrometre C2 condenser aperture
分子名称: CALCIUM ION, Proteinase K
著者Evans, G, Zhang, P, Beale, E.V, Waterman, D.G.
登録日2020-06-16
公開日2020-10-14
最終更新日2024-02-14
実験手法ELECTRON CRYSTALLOGRAPHY (2.701 Å)
主引用文献A Workflow for Protein Structure Determination From Thin Crystal Lamella by Micro-Electron Diffraction.
Front Mol Biosci, 7, 2020
6ZEV
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BU of 6zev by Molmil
Crystal structure of proteinase K lamellae by electron diffraction with a 20 micrometre C2 condenser aperture
分子名称: CALCIUM ION, Proteinase K
著者Evans, G, Zhang, P, Beale, E.V, Waterman, D.G.
登録日2020-06-16
公開日2020-10-14
最終更新日2024-02-14
実験手法ELECTRON CRYSTALLOGRAPHY (2.4 Å)
主引用文献A Workflow for Protein Structure Determination From Thin Crystal Lamella by Micro-Electron Diffraction.
Front Mol Biosci, 7, 2020
6ZEU
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BU of 6zeu by Molmil
Crystal structure of proteinase K lamella by electron diffraction with a 50 micrometre C2 condenser aperture
分子名称: CALCIUM ION, Proteinase K
著者Evans, G, Zhang, P, Beale, E.V, Waterman, D.G.
登録日2020-06-16
公開日2020-10-14
最終更新日2024-02-14
実験手法ELECTRON CRYSTALLOGRAPHY (2.004 Å)
主引用文献A Workflow for Protein Structure Determination From Thin Crystal Lamella by Micro-Electron Diffraction.
Front Mol Biosci, 7, 2020
4ZOJ
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BU of 4zoj by Molmil
Methylsulfanyl-containing inhibitor bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 4-methyl-2-{[2-methyl-6-(methylsulfanyl)phenyl]amino}benzoic acid, Anthranilate phosphoribosyltransferase, ...
著者Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2015-05-06
公開日2016-05-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Inhibitor bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD).
To be Published
4ZOF
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BU of 4zof by Molmil
Lobenzarit-like inhibitor bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-[(2-carboxy-5-nitrophenyl)amino]-3-methylbenzoic acid, Anthranilate phosphoribosyltransferase, ...
著者Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2015-05-06
公開日2016-05-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Inhibitor bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD).
To be Published
5BO2
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BU of 5bo2 by Molmil
Bianthranilate-like inhibitor with 4-atom "line" and phosphonate "hook" fishing for hydrogen bond donors in Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
分子名称: 2-[(2-carboxyphenyl)amino]-5-(3-phosphonopropoxy)benzoic acid, Anthranilate phosphoribosyltransferase, IMIDAZOLE
著者Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2015-05-27
公開日2016-06-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Binding and mimicking of the phosphate-rich substrate, PRPP.
To be Published
4ZOK
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BU of 4zok by Molmil
Methylsulfonyl-containing inhibitor bound in the substrate capture site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 4-methyl-2-{[2-methyl-6-(methylsulfonyl)phenyl]amino}benzoic acid, Anthranilate phosphoribosyltransferase, ...
著者Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2015-05-06
公開日2016-05-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Inhibitor bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD).
To be Published
5BYT
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BU of 5byt by Molmil
PRPP complexed with a single Mg in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, MAGNESIUM ION
著者Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2015-06-11
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Binding and mimicking of the phosphate-rich substrate, PRPP.
To be Published
5BO3
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BU of 5bo3 by Molmil
Bianthranilate-like inhibitor with 5 atom "line" and phosphonate "hook" fishing for hydrogen bond donors in Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
分子名称: 2-[(2-carboxyphenyl)amino]-5-(4-phosphonobutoxy)benzoic acid, Anthranilate phosphoribosyltransferase, IMIDAZOLE
著者Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2015-05-27
公開日2016-06-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Binding and mimicking of the phosphate-rich substrate, PRPP.
To be Published
5BNE
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BU of 5bne by Molmil
Bianthranilate-like inhibitor with 6 atom "line" and phosphonate "hook" fishing for hydrogen bond donors in Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
分子名称: 2-[(2-carboxyphenyl)amino]-5-[(5-phosphonopentyl)oxy]benzoic acid, Anthranilate phosphoribosyltransferase, IMIDAZOLE
著者Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2015-05-26
公開日2016-05-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Binding and mimicking of the phosphate-rich substrate, PRPP.
To be Published
5C1R
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BU of 5c1r by Molmil
Stereoisomer of PRPP bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyl (AnPRT; trpD)
分子名称: 5-O-[(R)-hydroxy(phosphonooxy)phosphoryl]-1-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, GLYCEROL, ...
著者Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2015-06-15
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献Binding and mimicking of the phosphate-rich substrate, PRPP.
To Be Published
5C7S
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BU of 5c7s by Molmil
PRPP complexed with two Mn2+ in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, MANGANESE (II) ION
著者Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2015-06-24
公開日2016-06-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Binding and mimicking of the phosphate-rich substrate, PRPP
To Be Published
1GWD
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BU of 1gwd by Molmil
Tri-iodide derivative of hen egg-white lysozyme
分子名称: 1,2-ETHANEDIOL, CARBON MONOXIDE, CHLORIDE ION, ...
著者Evans, G, Bricogne, G.
登録日2002-03-14
公開日2002-06-06
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Triiodide Derivatization and Combinatorial Counter-Ion Replacement: Two Methods for Enhancing Phasing Signal Using Laboratory Cu Kalpha X-Ray Equipment
Acta Crystallogr.,Sect.D, 58, 2002
1GWG
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BU of 1gwg by Molmil
Tri-iodide derivative of apoferritin
分子名称: CADMIUM ION, FERRITIN LIGHT CHAIN, IODIDE ION
著者Evans, G, Bricogne, G.
登録日2002-03-15
公開日2002-06-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Triiodide Derivatization and Combinatorial Counter-Ion Replacement: Two Methods for Enhancing Phasing Signal Using Laboratory Cu Kalpha X-Ray Equipment
Acta Crystallogr.,Sect.D, 58, 2002
1GW9
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BU of 1gw9 by Molmil
Tri-iodide derivative of Xylose Isomerase from Streptomyces Rubiginosus
分子名称: CALCIUM ION, IODIDE ION, XYLOSE ISOMERASE, ...
著者Evans, G, Bricogne, G.
登録日2002-03-13
公開日2002-06-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Triiodide Derivatization and Combinatorial Counter-Ion Replacement: Two Methods for Enhancing Phasing Signal Using Laboratory Cu Kalpha X-Ray Equipment
Acta Crystallogr.,Sect.D, 58, 2002
1GWA
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BU of 1gwa by Molmil
Triiodide derivative of porcine pancreas elastase
分子名称: CALCIUM ION, ELASTASE 1, IODIDE ION, ...
著者Evans, G, Bricogne, G.
登録日2002-03-13
公開日2002-06-06
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Triiodide Derivatization and Combinatorial Counter-Ion Replacement: Two Methods for Enhancing Phasing Signal Using Laboratory Cu Kalpha X-Ray Equipment
Acta Crystallogr.,Sect.D, 58, 2002
3L21
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BU of 3l21 by Molmil
The crystal structure of a dimeric mutant of dihydrodipicolinate synthase (DAPA, RV2753C) from Mycobacterium Tuberculosis - DHDPS-A204R
分子名称: ACETATE ION, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
著者Evans, G.L, Schuldt, L, Jamerson, G.B, Devenish, S.R, Weiss, M.S, Gerrard, J.A.
登録日2009-12-14
公開日2010-12-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A dimeric mutant of DHDPS from Mycobacterium tuberculosis
To be Published
4ZTV
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BU of 4ztv by Molmil
Non-anthranilate-like inhibitor (TAMU-A7) complexed with anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis in absence of PRPP
分子名称: 4,4,4-trifluoro-1-(4-methoxyphenyl)butane-1,3-dione, Anthranilate phosphoribosyltransferase
著者Evans, G.L, Eom, J, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2015-05-15
公開日2016-05-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Bioactive non-anthranilate-like fragment-like inhibitor provides alternative starting point for inhibitor design against anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis.
To be Published
5C2L
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BU of 5c2l by Molmil
Magnesium soaked into the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
分子名称: Anthranilate phosphoribosyltransferase, IMIDAZOLE, MAGNESIUM ION
著者Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2015-06-16
公開日2016-06-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.009 Å)
主引用文献Binding and mimicking of the phosphate-rich substrate, PRPP
To Be Published
1FKF
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BU of 1fkf by Molmil
ATOMIC STRUCTURE OF FKBP-FK506, AN IMMUNOPHILIN-IMMUNOSUPPRESSANT COMPLEX
分子名称: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, FK506 BINDING PROTEIN
著者Vanduyne, G.D, Standaert, R.F, Karplus, P.A, Schreiber, S.L, Clardy, J.
登録日1991-05-07
公開日1991-07-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex.
Science, 252, 1991
4M0R
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BU of 4m0r by Molmil
Trianthranilate-like analogue bound to anthranilate phosphoribosyltransferase (AnPRT; TrpD).
分子名称: 2,6-bis[(2-carboxyphenyl)amino]benzoic acid, Anthranilate phosphoribosyltransferase, DIMETHYL SULFOXIDE, ...
著者Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2013-08-02
公開日2014-05-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Repurposing the Chemical Scaffold of the Anti-Arthritic Drug Lobenzarit to Target Tryptophan Biosynthesis in Mycobacterium tuberculosis.
Chembiochem, 15, 2014
4GKM
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BU of 4gkm by Molmil
Bianthranilate-like analogue bound in the outer site of anthranilate phosphoribosyltransferase (AnPRT; trpD)
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-[(2-carboxyphenyl)amino]-5-methylbenzoic acid, Anthranilate phosphoribosyltransferase, ...
著者Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2012-08-13
公開日2013-08-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6683 Å)
主引用文献Repurposing the Chemical Scaffold of the Anti-Arthritic Drug Lobenzarit to Target Tryptophan Biosynthesis in Mycobacterium tuberculosis.
Chembiochem, 15, 2014
4GIU
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BU of 4giu by Molmil
Bianthranilate-like analogue bound in inner site of anthranilate phosphoribosyltransferase (AnPRT; trpD).
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-[(2-carboxy-5-methylphenyl)amino]-3-methylbenzoic acid, Anthranilate phosphoribosyltransferase, ...
著者Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2012-08-09
公開日2013-08-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.667 Å)
主引用文献Repurposing the Chemical Scaffold of the Anti-Arthritic Drug Lobenzarit to Target Tryptophan Biosynthesis in Mycobacterium tuberculosis.
Chembiochem, 15, 2014

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