5KEM
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![BU of 5kem by Molmil](/molmil-images/mine/5kem) | EBOV sGP in complex with variable Fab domains of IgGs c13C6 and BDBV91 | Descriptor: | BDBV91 variable Fab domain heavy chain, BDBV91 variable Fab domain light chain, Ebola secreted glycoprotein, ... | Authors: | Pallesen, J, Murin, C.D, de Val, N, Cottrell, C.A, Hastie, K.M, Turner, H.L, Fusco, M.L, Flyak, A.I, Zeitlin, L, Crowe Jr, J.E, Andersen, K.G, Saphire, E.O, Ward, A.B. | Deposit date: | 2016-06-09 | Release date: | 2016-09-07 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (5.5 Å) | Cite: | Structures of Ebola virus GP and sGP in complex with therapeutic antibodies. Nat Microbiol, 1, 2016
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2W0O
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![BU of 2w0o by Molmil](/molmil-images/mine/2w0o) | Horse spleen apoferritin | Descriptor: | CADMIUM ION, FERRITIN LIGHT CHAIN, SULFATE ION | Authors: | De Val, N, Declercq, J.P. | Deposit date: | 2008-08-20 | Release date: | 2008-08-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural Analysis of Haemin Demetallation by L-Chain Apoferritins J.Inorg.Biochem., 112, 2012
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2V2L
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![BU of 2v2l by Molmil](/molmil-images/mine/2v2l) | Mutant (E53,56,57,60Q) recombinant horse spleen apoferritin cocrystallized with haemin in acidic conditions | Descriptor: | CADMIUM ION, FERRITIN LIGHT CHAIN, GLYCEROL, ... | Authors: | De Val, N, Declercq, J.P. | Deposit date: | 2007-06-06 | Release date: | 2008-06-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Analysis of Haemin Demetallation by L-Chain Apoferritins J.Inorg.Biochem., 112, 2012
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2V2S
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![BU of 2v2s by Molmil](/molmil-images/mine/2v2s) | |
2V2O
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![BU of 2v2o by Molmil](/molmil-images/mine/2v2o) | |
2V2N
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![BU of 2v2n by Molmil](/molmil-images/mine/2v2n) | |
2V2J
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![BU of 2v2j by Molmil](/molmil-images/mine/2v2j) | |
2V2M
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![BU of 2v2m by Molmil](/molmil-images/mine/2v2m) | Mutant (E53,56,57,60Q) recombinant horse spleen apoferritin cocrystallized with haemin in basic conditions | Descriptor: | CADMIUM ION, FERRITIN LIGHT CHAIN, GLYCEROL, ... | Authors: | De Val, N, Declercq, J.P. | Deposit date: | 2007-06-06 | Release date: | 2008-06-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural Analysis of Haemin Demetallation by L-Chain Apoferritins J.Inorg.Biochem., 112, 2012
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2V2P
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![BU of 2v2p by Molmil](/molmil-images/mine/2v2p) | Mutant (E53,56,57,60Q and R59M) recombinant horse spleen apoferritin cocrystallized with haemin in acidic conditions | Descriptor: | CADMIUM ION, FERRITIN LIGHT CHAIN, GLYCEROL, ... | Authors: | De Val, N, Declercq, J.P. | Deposit date: | 2007-06-06 | Release date: | 2008-06-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Structural Analysis of Haemin Demetallation by L-Chain Apoferritins J.Inorg.Biochem., 112, 2012
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2V2I
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![BU of 2v2i by Molmil](/molmil-images/mine/2v2i) | |
2V2R
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![BU of 2v2r by Molmil](/molmil-images/mine/2v2r) | Mutant (E53,56,57,60Q and R59M) recombinant horse spleen apoferritin cocrystallized with haemin in basic conditions | Descriptor: | CADMIUM ION, FERRITIN LIGHT CHAIN, GLYCEROL, ... | Authors: | De Val, N, Declercq, J.P. | Deposit date: | 2007-06-06 | Release date: | 2008-06-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Analysis of Haemin Demetallation by L-Chain Apoferritins J.Inorg.Biochem., 112, 2012
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6N7W
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![BU of 6n7w by Molmil](/molmil-images/mine/6n7w) | Structure of bacteriophage T7 leading-strand DNA polymerase (D5A/E7A)/Trx in complex with a DNA fork and incoming dTTP (from multiple lead complexes) | Descriptor: | DNA (25-MER), DNA (77-MER), DNA-directed DNA polymerase, ... | Authors: | Gao, Y, Fox, T, Val, N, Yang, W. | Deposit date: | 2018-11-28 | Release date: | 2019-03-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structures and operating principles of the replisome. Science, 363, 2019
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6N9V
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![BU of 6n9v by Molmil](/molmil-images/mine/6n9v) | Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS1) | Descriptor: | DNA primase/helicase, DNA-directed DNA polymerase, MAGNESIUM ION, ... | Authors: | Gao, Y, Fox, T, Val, N, Yang, W. | Deposit date: | 2018-12-04 | Release date: | 2019-03-06 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structures and operating principles of the replisome. Science, 363, 2019
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6N9U
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![BU of 6n9u by Molmil](/molmil-images/mine/6n9u) | Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) interacting with primase domains of two gp4 subunits bound to an RNA/DNA hybrid and dTTP (from LagS1) | Descriptor: | DNA (44-MER), DNA primase/helicase, DNA-directed DNA polymerase, ... | Authors: | Gao, Y, Fox, T, Val, N, Yang, W. | Deposit date: | 2018-12-04 | Release date: | 2019-03-06 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structures and operating principles of the replisome. Science, 363, 2019
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6N9X
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![BU of 6n9x by Molmil](/molmil-images/mine/6n9x) | Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS3) | Descriptor: | DNA primase/helicase, DNA-directed DNA polymerase, MAGNESIUM ION, ... | Authors: | Gao, Y, Fox, T, Val, N, Yang, W. | Deposit date: | 2018-12-04 | Release date: | 2019-03-06 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structures and operating principles of the replisome. Science, 363, 2019
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6VO3
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![BU of 6vo3 by Molmil](/molmil-images/mine/6vo3) | AMC009 SOSIP.v4.2 in complex with PGV04 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AMC009 SOSIP.v4.2 envelope glycoprotein gp120, ... | Authors: | Cottrell, C.A, de Val, N, Ward, A.B. | Deposit date: | 2020-01-29 | Release date: | 2020-09-23 | Last modified: | 2020-12-09 | Method: | ELECTRON MICROSCOPY (4.25 Å) | Cite: | Neutralizing Antibody Responses Induced by HIV-1 Envelope Glycoprotein SOSIP Trimers Derived from Elite Neutralizers. J.Virol., 94, 2020
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6HMA
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![BU of 6hma by Molmil](/molmil-images/mine/6hma) | Improved model derived from cryo-EM map of Staphylococcus aureus large ribosomal subunit | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | Authors: | Eyal, Z, Cimicata, G, Matzov, D, Fox, T, de Val, N, Zimmerman, E, Bashan, A, Yonath, A. | Deposit date: | 2018-09-12 | Release date: | 2018-11-14 | Last modified: | 2020-05-27 | Method: | ELECTRON MICROSCOPY (2.65 Å) | Cite: | Improved model derived from cryo-EM map of Staphylococcus aureus large ribosomal subunit To Be Published
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4TX4
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![BU of 4tx4 by Molmil](/molmil-images/mine/4tx4) | Crystal Structure of a Single-Domain Cysteine Protease Inhibitor from Cowpea (Vigna unguiculata) | Descriptor: | Cysteine proteinase inhibitor, SULFATE ION | Authors: | Pereira, H.M, Valadares, N, Monteiro-Junior, J.E, Carvalho, C.P.S, Grangeiro, T.B. | Deposit date: | 2014-07-02 | Release date: | 2015-10-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Expression in Escherichia coli of cysteine protease inhibitors from cowpea (Vigna unguiculata): The crystal structure of a single-domain cystatin gives insights on its thermal and pH stability. Int. J. Biol. Macromol., 102, 2017
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7Q4G
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![BU of 7q4g by Molmil](/molmil-images/mine/7q4g) | Structure of coproheme decarboxylase from Corynebacterium dipththeriae Y135A mutant in complex with coproheme | Descriptor: | 1,3,5,8-TETRAMETHYL-PORPHINE-2,4,6,7-TETRAPROPIONIC ACID FERROUS COMPLEX, Coproheme decarboxylase from Corynebacterium diphtheriae Y135A mutant in complex with coproheme, DI(HYDROXYETHYL)ETHER | Authors: | Michlits, H, Valente, N, Mlynek, G, Hofbauer, S. | Deposit date: | 2021-10-30 | Release date: | 2022-02-23 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Initial Steps to Engineer Coproheme Decarboxylase to Obtain Stereospecific Monovinyl, Monopropionyl Deuterohemes. Front Bioeng Biotechnol, 9, 2021
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7Q4F
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![BU of 7q4f by Molmil](/molmil-images/mine/7q4f) | Structure of coproheme decarboxylase from Corynebacterium dipththeriae W183Y mutant in complex with coproheme | Descriptor: | 1,3,5,8-TETRAMETHYL-PORPHINE-2,4,6,7-TETRAPROPIONIC ACID FERROUS COMPLEX, Coproheme decarboxylase from Corynebacterium dipththeriae W183Y mutant in complex with coproheme, DI(HYDROXYETHYL)ETHER, ... | Authors: | Michlits, H, Valente, N, Mlynek, G, Hofbauer, S. | Deposit date: | 2021-10-30 | Release date: | 2022-02-23 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Initial Steps to Engineer Coproheme Decarboxylase to Obtain Stereospecific Monovinyl, Monopropionyl Deuterohemes. Front Bioeng Biotechnol, 9, 2021
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8FMW
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![BU of 8fmw by Molmil](/molmil-images/mine/8fmw) | The structure of a hibernating ribosome in the Lyme disease pathogen | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Sharma, M.R, Manjari, S.R, Agrawal, E.K, Keshavan, P, Koripella, R.K, Majumdar, S, Marcinkiewicz, A.L, Lin, Y.P, Agrawal, R.K, Banavali, N.K. | Deposit date: | 2022-12-25 | Release date: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | The structure of a hibernating ribosome in a Lyme disease pathogen. Nat Commun, 14, 2023
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8FN2
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![BU of 8fn2 by Molmil](/molmil-images/mine/8fn2) | The structure of a 50S ribosomal subunit in the Lyme disease pathogen Borreliella burgdorferi | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... | Authors: | Sharma, M.R, Manjari, S.R, Agrawal, E.K, Keshavan, P, Koripella, R.K, Majumdar, S, Marcinkiewicz, A.L, Lin, Y.P, Agrawal, R.K, Banavali, N.K. | Deposit date: | 2022-12-26 | Release date: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | The structure of a hibernating ribosome in a Lyme disease pathogen. Nat Commun, 14, 2023
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3IZY
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![BU of 3izy by Molmil](/molmil-images/mine/3izy) | Mammalian mitochondrial translation initiation factor 2 | Descriptor: | Translation initiation factor IF-2, mitochondrial, tRNA-Phe | Authors: | Yassin, A.S, Haque, E, Datta, P.P, Elmore, K, Banavali, N.K, Spremulli, L.L, Agrawal, R.K. | Deposit date: | 2011-01-19 | Release date: | 2011-03-23 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (10.8 Å) | Cite: | Insertion domain within mammalian mitochondrial translation initiation factor 2 serves the role of eubacterial initiation factor 1 Proc.Natl.Acad.Sci.USA, 108, 2011
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8HKR
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![BU of 8hkr by Molmil](/molmil-images/mine/8hkr) | Crystal Structure of Histone H3 Lysine 79 (H3K79) Methyltransferase Rv2067c from Mycobacterium tuberculosis | Descriptor: | PHOSPHATE ION, Protein lysine methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Dadireddy, V, Singh, P.R, Kalladi, S.M, Valakunja, N, Ramakumar, S. | Deposit date: | 2022-11-28 | Release date: | 2023-10-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The Mycobacterium tuberculosis methyltransferase Rv2067c manipulates host epigenetic programming to promote its own survival. Nat Commun, 14, 2023
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5LPG
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![BU of 5lpg by Molmil](/molmil-images/mine/5lpg) | Structure of NUDT15 in complex with 6-thio-GMP | Descriptor: | MAGNESIUM ION, Probable 8-oxo-dGTP diphosphatase NUDT15, [(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-sulfanyl-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate | Authors: | Masuyer, G, Carter, M, Rehling, D, Stenmark, P, Helleday, T, Jemth, A.-S, Valerie, N.C.K, Homan, E, Herr, P, Bevc, L, Page, B.D.G, Hagenkort, A. | Deposit date: | 2016-08-12 | Release date: | 2016-08-24 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | NUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine. Cancer Res., 76, 2016
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