8HKR

Crystal Structure of Histone H3 Lysine 79 (H3K79) Methyltransferase Rv2067c from Mycobacterium tuberculosis

Summary for 8HKR

• Entry DOI: 10.2210/pdb8hkr/pdb
• Descriptor: Protein lysine methyltransferase, PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ... (4 entities in total)
• Functional Keywords: mycobacterium tuberculosis, sam-binding, class i methyltransferase, dimerization domain, transferase
• Biological source: Mycobacterium tuberculosis H37Rv
• Total number of polymer chains: 2
• Total formula weight: 93392.05

Authors

Dadireddy, V.,Singh, P.R.,Kalladi, S.M.,Valakunja, N.,Ramakumar, S. (deposition date: 2022-11-28, release date: 2023-10-18, Last modification date: 2024-01-24)

• Primary citation: Singh, P.R.,Dadireddy, V.,Udupa, S.,Kalladi, S.M.,Shee, S.,Khosla, S.,Rajmani, R.S.,Singh, A.,Ramakumar, S.,Nagaraja, V.; The Mycobacterium tuberculosis methyltransferase Rv2067c manipulates host epigenetic programming to promote its own survival.; Nat Commun, 14:8497-8497, 2023; PubMed: 38129415; DOI: 10.1038/s41467-023-43940-6

Experimental method

X-RAY DIFFRACTION (2.4 Å)