PDB Search results for query - 日本蛋白质结构数据库

PDB: 22 results

Crystal structure of GlpG in complex with peptide boronate inhibitor
Descriptor:	ACE-VAL-ARG-MET-B2A, Rhomboid family intramembrane serine protease GlpG
Authors:	Urban, S, Cho, S.
Deposit date:	2020-01-15
Release date:	2020-09-16
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Designed Parasite-Selective Rhomboid Inhibitors Block Invasion and Clear Blood-Stage Malaria. Cell Chem Biol, 27, 2020

6VJ8

Crystal structure of GlpG in complex with peptide chloromethylketone inhibitor
Descriptor:	Peptide chloromethylketone inhibitor, Rhomboid family intramembrane serine protease GlpG
Authors:	Urban, S, Cho, S.
Deposit date:	2020-01-15
Release date:	2020-09-16
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Designed Parasite-Selective Rhomboid Inhibitors Block Invasion and Clear Blood-Stage Malaria. Cell Chem Biol, 27, 2020

6XRO

Crystal structure of GlpG in complex with peptide boronate inhibitor, Ac-KRFRSMQYSA-B(OH)2
Descriptor:	CHLORIDE ION, Rhomboid protease GlpG, SODIUM ION, ...
Authors:	Urban, S, Cho, S.
Deposit date:	2020-07-13
Release date:	2020-09-16
Last modified:	2024-10-09
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Designed Parasite-Selective Rhomboid Inhibitors Block Invasion and Clear Blood-Stage Malaria. Cell Chem Biol, 27, 2020

6XRP

Crystal structure of GlpG in complex with peptide ketoamide inhibitor, Ac-RVWHA-ketoamide-phenylbutyl
Descriptor:	N-(4-phenylbutyl)formamide, Rhomboid protease GlpG, peptide ketoamide inhibitor
Authors:	Urban, S, Cho, S.
Deposit date:	2020-07-13
Release date:	2020-09-16
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Designed Parasite-Selective Rhomboid Inhibitors Block Invasion and Clear Blood-Stage Malaria. Cell Chem Biol, 27, 2020

5F5J

E.coli GlpG Y205F mutant complexed with aldehyde inhibitor in DMPC/CHAPSO bicelle
Descriptor:	Rhomboid protease GlpG, peptidic derivative of Gurken: ACE-VAL-ARG-MET-ALA-aldehyde
Authors:	Urban, S, Cho, S, Dickey, S.
Deposit date:	2015-12-04
Release date:	2016-02-10
Last modified:	2024-07-10
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis. Mol.Cell, 61, 2016

5F5B

Structure of E.Coli GlpG complexed with peptidic inhibitor Ac-VRMA-CHO
Descriptor:	Rhomboid protease GlpG, peptidic derivative of Gurken: ACE-VAL-ARG-MET-ALA-aldehyde
Authors:	Urban, S, Cho, S, Dickey, S.W.
Deposit date:	2015-12-04
Release date:	2016-02-17
Last modified:	2024-07-10
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis. Mol.Cell, 61, 2016

5F5D

Crystal structures and Inhibition kinetics reveal a two-state catalytic mechanism with drug design implications for rhomboid proteolysis
Descriptor:	Rhomboid protease GlpG
Authors:	Urban, S, Cho, S, Dickey, S.W.
Deposit date:	2015-12-04
Release date:	2016-02-24
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis. Mol.Cell, 61, 2016

5F5G

Structure of E.Coli GlpG Y205F mutant complexed with peptidic inhibitor Ac-RMA-CHO in the DMPC/CHAPSO bicelle
Descriptor:	ACE-ARG-MET-ALA-aldehyde, Rhomboid protease GlpG
Authors:	Urban, S, Cho, S, Dickey, S.W.
Deposit date:	2015-12-04
Release date:	2016-04-06
Last modified:	2024-07-10
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis. Mol.Cell, 61, 2016

5F5K

E.Coli GlpG Y205F mutant complexed with aldehyde inhibitor in DMPC/CHAPSO bicelle
Descriptor:	Peptidic derivative of Gurken: ACE-ARG-LYS-VAL-ARG-MET-ALA-aldehyde, Rhomboid protease GlpG
Authors:	Urban, S, Cho, S, Dickey, S.W.
Deposit date:	2015-12-04
Release date:	2016-02-10
Last modified:	2024-07-10
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis. Mol.Cell, 61, 2016

6PJU

Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
Descriptor:	Peptide aldehyde inhibitor, Rhomboid protease GlpG
Authors:	Urban, S, Cho, S.
Deposit date:	2019-06-28
Release date:	2019-11-27
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release. Nat.Struct.Mol.Biol., 26, 2019

6PJR

Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
Descriptor:	CHLORIDE ION, Peptide aldehyde inhibitor, Rhomboid protease GlpG
Authors:	Urban, S, Cho, S.
Deposit date:	2019-06-28
Release date:	2019-10-02
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release. Nat.Struct.Mol.Biol., 26, 2019

6PJA

Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
Descriptor:	Peptide aldehyde inhibitor, Rhomboid protease GlpG
Authors:	Urban, S, Cho, S.
Deposit date:	2019-06-28
Release date:	2019-10-02
Last modified:	2024-03-13
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release. Nat.Struct.Mol.Biol., 26, 2019

6PJ5

Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
Descriptor:	Peptide aldehyde inhibitor, Rhomboid protease GlpG
Authors:	Urban, S, Cho, S.
Deposit date:	2019-06-27
Release date:	2019-10-02
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release. Nat.Struct.Mol.Biol., 26, 2019

6PJ9

Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
Descriptor:	Peptide aldehyde inhibitor, Rhomboid protease GlpG
Authors:	Urban, S, Cho, S.
Deposit date:	2019-06-28
Release date:	2019-10-02
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release. Nat.Struct.Mol.Biol., 26, 2019

6PJ7

Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
Descriptor:	Peptide aldehyde inhibitor, Rhomboid protease GlpG
Authors:	Urban, S, Cho, S.
Deposit date:	2019-06-28
Release date:	2019-10-02
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release. Nat.Struct.Mol.Biol., 26, 2019

6PJQ

Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
Descriptor:	Peptide aldehyde inhibitor, Rhomboid protease GlpG
Authors:	Urban, S, Cho, S.
Deposit date:	2019-06-28
Release date:	2019-11-27
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release. Nat.Struct.Mol.Biol., 26, 2019

6PJ8

Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
Descriptor:	Peptide aldehyde inhibitor, Rhomboid protease GlpG
Authors:	Urban, S, Cho, S.
Deposit date:	2019-06-28
Release date:	2019-10-02
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release. Nat.Struct.Mol.Biol., 26, 2019

6PJP

Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
Descriptor:	Peptide aldehyde inhibitor, Rhomboid protease GlpG
Authors:	Urban, S, Cho, S.
Deposit date:	2019-06-28
Release date:	2019-10-02
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.45 Å)
Cite:	Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release. Nat.Struct.Mol.Biol., 26, 2019

6PJ4

Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
Descriptor:	Peptide aldehyde inhibitor, Rhomboid protease GlpG
Authors:	Urban, S, Cho, S.
Deposit date:	2019-06-27
Release date:	2019-10-02
Last modified:	2024-03-13
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release. Nat.Struct.Mol.Biol., 26, 2019

8RQF

Cryo-EM structure of human NTCP-Bulevirtide complex
Descriptor:	Fab-specific nanobody, Heavy chain of Fab3, Light chain of Fab3, ...
Authors:	Liu, H, Zakrzewicz, D, Nosol, K, Irobalieva, R.N, Mukherjee, S, Bang-Soerensen, R, Goldmann, N, Kunz, S, Rossi, L, Kossiakoff, A.A, Urban, S, Glebe, D, Geyer, J, Locher, K.P.
Deposit date:	2024-01-18
Release date:	2024-03-27
Last modified:	2024-10-23
Method:	ELECTRON MICROSCOPY (3.41 Å)
Cite:	Structure of antiviral drug bulevirtide bound to hepatitis B and D virus receptor protein NTCP. Nat Commun, 15, 2024

4NJP

Proteolysis inside the membrane is a rate-governed reaction not Driven by substrate affinity
Descriptor:	Rhomboid protease GlpG
Authors:	Dickey, S.W, Baker, R.P, Cho, S, Urban, S.
Deposit date:	2013-11-11
Release date:	2013-12-25
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Proteolysis inside the Membrane Is a Rate-Governed Reaction Not Driven by Substrate Affinity. Cell(Cambridge,Mass.), 155, 2013

4NJN

Crystal Structure of E.coli GlpG at pH 4.5
Descriptor:	Rhomboid protease GlpG
Authors:	Dickey, S.W, Baker, R.P, Cho, S, Urban, S.
Deposit date:	2013-11-11
Release date:	2013-12-25
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Proteolysis inside the Membrane Is a Rate-Governed Reaction Not Driven by Substrate Affinity. Cell(Cambridge,Mass.), 155, 2013

Total results:	22
Displayed results:	22
Sorted by:	Hit score (from highest)
Deposition authors:	"Urban, S."