6XRO

Crystal structure of GlpG in complex with peptide boronate inhibitor, Ac-KRFRSMQYSA-B(OH)2

Summary for 6XRO

Entry DOI	10.2210/pdb6xro/pdb
Descriptor	Rhomboid protease GlpG, peptide boronate inhibitor, ALANINE BORONIC ACID, ... (6 entities in total)
Functional Keywords	glpg, rhomboid protease, hydrolase-hydrolase inhibitor complex, membrane protein, hydrolase/hydrolase inhibitor
Biological source	Escherichia coli More
Total number of polymer chains	2
Total formula weight	25298.41
Authors	Urban, S.,Cho, S. (deposition date: 2020-07-13, release date: 2020-09-16, Last modification date: 2023-11-15)
Primary citation	Gandhi, S.,Baker, R.P.,Cho, S.,Stanchev, S.,Strisovsky, K.,Urban, S. Designed Parasite-Selective Rhomboid Inhibitors Block Invasion and Clear Blood-Stage Malaria. Cell Chem Biol, 27:1410-1424.e6, 2020 Cited by PubMed: 32888502 DOI: 10.1016/j.chembiol.2020.08.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation