6XRO
Crystal structure of GlpG in complex with peptide boronate inhibitor, Ac-KRFRSMQYSA-B(OH)2
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue B2A B 501 |
| Chain | Residue |
| A | GLY198 |
| A | NA304 |
| A | HOH623 |
| B | SER500 |
| A | GLY199 |
| A | LEU200 |
| A | SER201 |
| A | GLY202 |
| A | ALA250 |
| A | ALA253 |
| A | HIS254 |
| A | NA303 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 301 |
| Chain | Residue |
| A | GLN189 |
| A | SER193 |
| A | ASN251 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 302 |
| Chain | Residue |
| A | ARG92 |
| A | ALA93 |
| A | TRP159 |
| A | GLN226 |
| A | GLY228 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 303 |
| Chain | Residue |
| A | SER201 |
| A | MET249 |
| A | HIS254 |
| B | B2A501 |
| A | HOH622 |
| A | HOH630 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 304 |
| Chain | Residue |
| A | HIS150 |
| A | ASN154 |
| B | B2A501 |
| A | HOH636 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"17051161","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"17099694","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"17190827","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"17277078","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"17051161","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"17099694","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"17190827","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"17277078","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=1","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 30 |
| Details | Topological domain: {"description":"Periplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=2","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 14 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=3","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=4","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 22 |
| Details | Transmembrane: {"description":"Helical; Name=5","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 22 |
| Details | Transmembrane: {"description":"Helical; Name=6","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
