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PDB: 22 件

6VJ8
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BU of 6vj8 by Molmil
Crystal structure of GlpG in complex with peptide chloromethylketone inhibitor
分子名称: Peptide chloromethylketone inhibitor, Rhomboid family intramembrane serine protease GlpG
著者Urban, S, Cho, S.
登録日2020-01-15
公開日2020-09-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Designed Parasite-Selective Rhomboid Inhibitors Block Invasion and Clear Blood-Stage Malaria.
Cell Chem Biol, 27, 2020
6VJ9
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BU of 6vj9 by Molmil
Crystal structure of GlpG in complex with peptide boronate inhibitor
分子名称: ACE-VAL-ARG-MET-B2A, Rhomboid family intramembrane serine protease GlpG
著者Urban, S, Cho, S.
登録日2020-01-15
公開日2020-09-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Designed Parasite-Selective Rhomboid Inhibitors Block Invasion and Clear Blood-Stage Malaria.
Cell Chem Biol, 27, 2020
6XRP
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BU of 6xrp by Molmil
Crystal structure of GlpG in complex with peptide ketoamide inhibitor, Ac-RVWHA-ketoamide-phenylbutyl
分子名称: N-(4-phenylbutyl)formamide, Rhomboid protease GlpG, peptide ketoamide inhibitor
著者Urban, S, Cho, S.
登録日2020-07-13
公開日2020-09-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Designed Parasite-Selective Rhomboid Inhibitors Block Invasion and Clear Blood-Stage Malaria.
Cell Chem Biol, 27, 2020
6XRO
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BU of 6xro by Molmil
Crystal structure of GlpG in complex with peptide boronate inhibitor, Ac-KRFRSMQYSA-B(OH)2
分子名称: CHLORIDE ION, Rhomboid protease GlpG, SODIUM ION, ...
著者Urban, S, Cho, S.
登録日2020-07-13
公開日2020-09-16
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Designed Parasite-Selective Rhomboid Inhibitors Block Invasion and Clear Blood-Stage Malaria.
Cell Chem Biol, 27, 2020
5F5J
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BU of 5f5j by Molmil
E.coli GlpG Y205F mutant complexed with aldehyde inhibitor in DMPC/CHAPSO bicelle
分子名称: Rhomboid protease GlpG, peptidic derivative of Gurken: ACE-VAL-ARG-MET-ALA-aldehyde
著者Urban, S, Cho, S, Dickey, S.
登録日2015-12-04
公開日2016-02-10
最終更新日2016-02-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis.
Mol.Cell, 61, 2016
5F5B
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BU of 5f5b by Molmil
Structure of E.Coli GlpG complexed with peptidic inhibitor Ac-VRMA-CHO
分子名称: Rhomboid protease GlpG, peptidic derivative of Gurken: ACE-VAL-ARG-MET-ALA-aldehyde
著者Urban, S, Cho, S, Dickey, S.W.
登録日2015-12-04
公開日2016-02-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis.
Mol.Cell, 61, 2016
5F5D
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BU of 5f5d by Molmil
Crystal structures and Inhibition kinetics reveal a two-state catalytic mechanism with drug design implications for rhomboid proteolysis
分子名称: Rhomboid protease GlpG
著者Urban, S, Cho, S, Dickey, S.W.
登録日2015-12-04
公開日2016-02-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis.
Mol.Cell, 61, 2016
5F5G
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BU of 5f5g by Molmil
Structure of E.Coli GlpG Y205F mutant complexed with peptidic inhibitor Ac-RMA-CHO in the DMPC/CHAPSO bicelle
分子名称: ACE-ARG-MET-ALA-aldehyde, Rhomboid protease GlpG
著者Urban, S, Cho, S, Dickey, S.W.
登録日2015-12-04
公開日2016-04-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis.
Mol.Cell, 61, 2016
5F5K
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BU of 5f5k by Molmil
E.Coli GlpG Y205F mutant complexed with aldehyde inhibitor in DMPC/CHAPSO bicelle
分子名称: Peptidic derivative of Gurken: ACE-ARG-LYS-VAL-ARG-MET-ALA-aldehyde, Rhomboid protease GlpG
著者Urban, S, Cho, S, Dickey, S.W.
登録日2015-12-04
公開日2016-02-10
最終更新日2016-02-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis.
Mol.Cell, 61, 2016
6PJU
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BU of 6pju by Molmil
Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
分子名称: Peptide aldehyde inhibitor, Rhomboid protease GlpG
著者Urban, S, Cho, S.
登録日2019-06-28
公開日2019-11-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
Nat.Struct.Mol.Biol., 26, 2019
6PJR
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BU of 6pjr by Molmil
Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
分子名称: CHLORIDE ION, Peptide aldehyde inhibitor, Rhomboid protease GlpG
著者Urban, S, Cho, S.
登録日2019-06-28
公開日2019-10-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
Nat.Struct.Mol.Biol., 26, 2019
6PJA
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BU of 6pja by Molmil
Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
分子名称: Peptide aldehyde inhibitor, Rhomboid protease GlpG
著者Urban, S, Cho, S.
登録日2019-06-28
公開日2019-10-02
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
Nat.Struct.Mol.Biol., 26, 2019
6PJ5
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BU of 6pj5 by Molmil
Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
分子名称: Peptide aldehyde inhibitor, Rhomboid protease GlpG
著者Urban, S, Cho, S.
登録日2019-06-27
公開日2019-10-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
Nat.Struct.Mol.Biol., 26, 2019
6PJ9
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BU of 6pj9 by Molmil
Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
分子名称: Peptide aldehyde inhibitor, Rhomboid protease GlpG
著者Urban, S, Cho, S.
登録日2019-06-28
公開日2019-10-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
Nat.Struct.Mol.Biol., 26, 2019
6PJ7
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BU of 6pj7 by Molmil
Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
分子名称: Peptide aldehyde inhibitor, Rhomboid protease GlpG
著者Urban, S, Cho, S.
登録日2019-06-28
公開日2019-10-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
Nat.Struct.Mol.Biol., 26, 2019
6PJQ
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BU of 6pjq by Molmil
Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
分子名称: Peptide aldehyde inhibitor, Rhomboid protease GlpG
著者Urban, S, Cho, S.
登録日2019-06-28
公開日2019-11-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
Nat.Struct.Mol.Biol., 26, 2019
6PJ8
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BU of 6pj8 by Molmil
Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
分子名称: Peptide aldehyde inhibitor, Rhomboid protease GlpG
著者Urban, S, Cho, S.
登録日2019-06-28
公開日2019-10-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
Nat.Struct.Mol.Biol., 26, 2019
6PJP
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BU of 6pjp by Molmil
Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
分子名称: Peptide aldehyde inhibitor, Rhomboid protease GlpG
著者Urban, S, Cho, S.
登録日2019-06-28
公開日2019-10-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
Nat.Struct.Mol.Biol., 26, 2019
6PJ4
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BU of 6pj4 by Molmil
Time-resolved structural snapshot of proteolysis by GlpG inside the membrane
分子名称: Peptide aldehyde inhibitor, Rhomboid protease GlpG
著者Urban, S, Cho, S.
登録日2019-06-27
公開日2019-10-02
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
Nat.Struct.Mol.Biol., 26, 2019
8RQF
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BU of 8rqf by Molmil
Cryo-EM structure of human NTCP-Bulevirtide complex
分子名称: Fab-specific nanobody, Heavy chain of Fab3, Light chain of Fab3, ...
著者Liu, H, Zakrzewicz, D, Nosol, K, Irobalieva, R.N, Mukherjee, S, Bang-Soerensen, R, Goldmann, N, Kunz, S, Rossi, L, Kossiakoff, A.A, Urban, S, Glebe, D, Geyer, J, Locher, K.P.
登録日2024-01-18
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Cryo-EM structure of human NTCP-Bulevirtide complex
To Be Published
4NJP
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BU of 4njp by Molmil
Proteolysis inside the membrane is a rate-governed reaction not Driven by substrate affinity
分子名称: Rhomboid protease GlpG
著者Dickey, S.W, Baker, R.P, Cho, S, Urban, S.
登録日2013-11-11
公開日2013-12-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Proteolysis inside the Membrane Is a Rate-Governed Reaction Not Driven by Substrate Affinity.
Cell(Cambridge,Mass.), 155, 2013
4NJN
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BU of 4njn by Molmil
Crystal Structure of E.coli GlpG at pH 4.5
分子名称: Rhomboid protease GlpG
著者Dickey, S.W, Baker, R.P, Cho, S, Urban, S.
登録日2013-11-11
公開日2013-12-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Proteolysis inside the Membrane Is a Rate-Governed Reaction Not Driven by Substrate Affinity.
Cell(Cambridge,Mass.), 155, 2013

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件を2024-07-03に公開中

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