2R8E
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![BU of 2r8e by Molmil](/molmil-images/mine/2r8e) | Crystal structure of YrbI from Escherichia coli in complex with Mg | Descriptor: | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, CHLORIDE ION, MAGNESIUM ION | Authors: | Tsodikov, O.V, Aggarwal, P, Rubin, J.R, Stuckey, J.A, Woodard, R, Biswas, T. | Deposit date: | 2007-09-10 | Release date: | 2008-09-23 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | The Tail of KdsC: CONFORMATIONAL CHANGES CONTROL THE ACTIVITY OF A HALOACID DEHALOGENASE SUPERFAMILY PHOSPHATASE. J.Biol.Chem., 284, 2009
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2A1J
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![BU of 2a1j by Molmil](/molmil-images/mine/2a1j) | Crystal Structure of the Complex between the C-Terminal Domains of Human XPF and ERCC1 | Descriptor: | DNA excision repair protein ERCC-1, DNA repair endonuclease XPF, MERCURY (II) ION | Authors: | Tsodikov, O.V, Enzlin, J.H, Scharer, O.D, Ellenberger, T. | Deposit date: | 2005-06-20 | Release date: | 2005-08-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure and DNA binding functions of ERCC1, a subunit of the DNA structure-specific endonuclease XPF-ERCC1. Proc.Natl.Acad.Sci.Usa, 102, 2005
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2A1I
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![BU of 2a1i by Molmil](/molmil-images/mine/2a1i) | Crystal Structure of the Central Domain of Human ERCC1 | Descriptor: | DNA excision repair protein ERCC-1, MERCURY (II) ION | Authors: | Tsodikov, O.V, Enzlin, J.H, Scharer, O.D, Ellenberger, T. | Deposit date: | 2005-06-20 | Release date: | 2005-08-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure and DNA binding functions of ERCC1, a subunit of the DNA structure-specific endonuclease XPF-ERCC1. Proc.Natl.Acad.Sci.Usa, 102, 2005
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3PVP
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![BU of 3pvp by Molmil](/molmil-images/mine/3pvp) | Structure of Mycobacterium tuberculosis DnaA-DBD in complex with box2 DNA | Descriptor: | Chromosomal replication initiator protein dnaA, DNA (5'-D(*CP*GP*TP*TP*AP*TP*CP*CP*AP*CP*AP*AP*C)-3'), DNA (5'-D(*GP*TP*TP*GP*TP*GP*GP*AP*TP*AP*AP*CP*G)-3') | Authors: | Tsodikov, O.V, Biswas, T. | Deposit date: | 2010-12-07 | Release date: | 2011-05-25 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and Thermodynamic Signatures of DNA Recognition by Mycobacterium tuberculosis DnaA. J.Mol.Biol., 410, 2011
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3PVV
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![BU of 3pvv by Molmil](/molmil-images/mine/3pvv) | Structure of Mycobacterium tuberculosis DnaA-DBD in complex with box1 DNA | Descriptor: | Chromosomal replication initiator protein dnaA, DNA (5'-D(*CP*GP*TP*TP*GP*TP*CP*CP*AP*CP*AP*AP*C)-3'), DNA (5'-D(*GP*TP*TP*GP*TP*GP*GP*AP*CP*AP*AP*CP*G)-3') | Authors: | Tsodikov, O.V, Biswas, T. | Deposit date: | 2010-12-07 | Release date: | 2011-05-25 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and Thermodynamic Signatures of DNA Recognition by Mycobacterium tuberculosis DnaA. J.Mol.Biol., 410, 2011
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2R8Z
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![BU of 2r8z by Molmil](/molmil-images/mine/2r8z) | Crystal structure of YrbI phosphatase from Escherichia coli in complex with a phosphate and a calcium ion | Descriptor: | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, CALCIUM ION, PHOSPHATE ION | Authors: | Tsodikov, O.V, Aggarwal, P, Rubin, J.R, Stuckey, J.A, Woodard, R.W, Biswas, T. | Deposit date: | 2007-09-11 | Release date: | 2008-09-23 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Tail of KdsC: CONFORMATIONAL CHANGES CONTROL THE ACTIVITY OF A HALOACID DEHALOGENASE SUPERFAMILY PHOSPHATASE. J.Biol.Chem., 284, 2009
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2R8X
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![BU of 2r8x by Molmil](/molmil-images/mine/2r8x) | Crystal structure of YrbI phosphatase from Escherichia coli | Descriptor: | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, CHLORIDE ION | Authors: | Tsodikov, O.V, Aggarwal, P, Rubin, J.R, Stuckey, J.A, Woodard, R.W, Biswas, T. | Deposit date: | 2007-09-11 | Release date: | 2008-09-23 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The Tail of KdsC: CONFORMATIONAL CHANGES CONTROL THE ACTIVITY OF A HALOACID DEHALOGENASE SUPERFAMILY PHOSPHATASE. J.Biol.Chem., 284, 2009
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2R8Y
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![BU of 2r8y by Molmil](/molmil-images/mine/2r8y) | Crystal structure of YrbI phosphatase from Escherichia coli in a complex with Ca | Descriptor: | CALCIUM ION, CHLORIDE ION, YrbI from Escherichia coli | Authors: | Tsodikov, O.V, Aggarwal, P, Rubin, J.R, Stuckey, J.A, Woodard, R.W, Biswas, T. | Deposit date: | 2007-09-11 | Release date: | 2008-09-23 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The Tail of KdsC: CONFORMATIONAL CHANGES CONTROL THE ACTIVITY OF A HALOACID DEHALOGENASE SUPERFAMILY PHOSPHATASE. J.Biol.Chem., 284, 2009
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2JNW
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![BU of 2jnw by Molmil](/molmil-images/mine/2jnw) | Solution structure of a ERCC1-XPA heterodimer | Descriptor: | DNA excision repair protein ERCC-1, DNA-repair protein complementing XP-A cells | Authors: | Tsodikov, O.V, Ivanov, D, Orelli, B, Staresincic, L, Scharer, O.D, Wagner, G. | Deposit date: | 2007-02-07 | Release date: | 2007-10-30 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Structural basis for the recruitment of ERCC1-XPF to nucleotide excision repair complexes by XPA Embo J., 26, 2007
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3HYC
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![BU of 3hyc by Molmil](/molmil-images/mine/3hyc) | |
4RVH
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![BU of 4rvh by Molmil](/molmil-images/mine/4rvh) | Crystal structure of MtmC in complex with SAH and TDP-4-keto-D-olivose | Descriptor: | D-mycarose 3-C-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ... | Authors: | Tsodikov, O.V, Hou, C, Chen, J.-M, Rohr, J. | Deposit date: | 2014-11-26 | Release date: | 2015-01-28 | Last modified: | 2015-05-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Insight into MtmC, a Bifunctional Ketoreductase-Methyltransferase Involved in the Assembly of the Mithramycin Trisaccharide Chain. Biochemistry, 54, 2015
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4RVG
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![BU of 4rvg by Molmil](/molmil-images/mine/4rvg) | Crystal structure of MtmC in complex with SAM and TDP | Descriptor: | ACETATE ION, D-mycarose 3-C-methyltransferase, S-ADENOSYLMETHIONINE, ... | Authors: | Tsodikov, O.V, Hou, C, Chen, J.-M, Rohr, J. | Deposit date: | 2014-11-26 | Release date: | 2015-01-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Insight into MtmC, a Bifunctional Ketoreductase-Methyltransferase Involved in the Assembly of the Mithramycin Trisaccharide Chain. Biochemistry, 54, 2015
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4RVD
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![BU of 4rvd by Molmil](/molmil-images/mine/4rvd) | Crystal structure of MtmC in complex with SAM | Descriptor: | ACETATE ION, D-mycarose 3-C-methyltransferase, S-ADENOSYLMETHIONINE, ... | Authors: | Tsodikov, O.V, Hou, C, Chen, J.-M, Rohr, J. | Deposit date: | 2014-11-26 | Release date: | 2015-01-28 | Last modified: | 2015-05-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Insight into MtmC, a Bifunctional Ketoreductase-Methyltransferase Involved in the Assembly of the Mithramycin Trisaccharide Chain. Biochemistry, 54, 2015
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4RVF
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![BU of 4rvf by Molmil](/molmil-images/mine/4rvf) | Crystal structure of MtmC in complex with TDP | Descriptor: | D-mycarose 3-C-methyltransferase, THYMIDINE-5'-DIPHOSPHATE, ZINC ION | Authors: | Tsodikov, O.V, Hou, C, Chen, J.-M, Rohr, J. | Deposit date: | 2014-11-26 | Release date: | 2015-01-28 | Last modified: | 2015-05-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Insight into MtmC, a Bifunctional Ketoreductase-Methyltransferase Involved in the Assembly of the Mithramycin Trisaccharide Chain. Biochemistry, 54, 2015
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3R1K
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![BU of 3r1k by Molmil](/molmil-images/mine/3r1k) | Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis H37Rv in complex with CoA and an acetamide moiety | Descriptor: | ACETAMIDE, COENZYME A, Enhanced intracellular survival protein | Authors: | Biswas, T, Chen, W, Garneau-Tsodikova, S, Tsodikov, O.V. | Deposit date: | 2011-03-10 | Release date: | 2011-06-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Unusual regioversatility of acetyltransferase Eis, a cause of drug resistance in XDR-TB. Proc.Natl.Acad.Sci.USA, 108, 2011
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3U9F
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![BU of 3u9f by Molmil](/molmil-images/mine/3u9f) | |
3U9B
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![BU of 3u9b by Molmil](/molmil-images/mine/3u9b) | Structure of apo-CATI | Descriptor: | Chloramphenicol acetyltransferase | Authors: | Biswas, T, Garneau-Tsodikova, S, Tsodikov, O.V. | Deposit date: | 2011-10-18 | Release date: | 2012-02-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The structural basis for substrate versatility of chloramphenicol acetyltransferase CAT(I). Protein Sci., 21, 2012
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5WHF
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![BU of 5whf by Molmil](/molmil-images/mine/5whf) | |
8G7F
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![BU of 8g7f by Molmil](/molmil-images/mine/8g7f) | Crystal Structure of FosB from Bacillus cereus with Zinc and 1-hydroxypropylphosphonic acid | Descriptor: | FORMIC ACID, GLYCEROL, MAGNESIUM ION, ... | Authors: | Travis, S, Pang, A.H, Tsodikov, O.V, Garneau-Tsodikova, S, Thompson, M.K. | Deposit date: | 2023-02-16 | Release date: | 2023-06-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Identification and analysis of small molecule inhibitors of FosB from Staphylococcus aureus. Rsc Med Chem, 14, 2023
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8G7G
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![BU of 8g7g by Molmil](/molmil-images/mine/8g7g) | Crystal Structure of FosB from Bacillus cereus with Zinc and (1-hydroxy-2-methylpropyl)phosphonic acid | Descriptor: | FORMIC ACID, MAGNESIUM ION, Metallothiol transferase FosB, ... | Authors: | Travis, S, Pang, A.H, Tsodikov, O.V, Garneau-Tsodikova, S, Thompson, M.K. | Deposit date: | 2023-02-16 | Release date: | 2023-06-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Identification and analysis of small molecule inhibitors of FosB from Staphylococcus aureus. Rsc Med Chem, 14, 2023
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8G7H
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![BU of 8g7h by Molmil](/molmil-images/mine/8g7h) | Crystal Structure of FosB from Bacillus cereus with Zinc and (1-hydroxypropan-2-yl)phosphonic acid | Descriptor: | FORMIC ACID, GLYCEROL, MAGNESIUM ION, ... | Authors: | Travis, S, Pang, A.H, Tsodikov, O.V, Garneau-Tsodikova, S, Thompson, M.K. | Deposit date: | 2023-02-16 | Release date: | 2023-06-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Identification and analysis of small molecule inhibitors of FosB from Staphylococcus aureus. Rsc Med Chem, 14, 2023
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8G7I
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![BU of 8g7i by Molmil](/molmil-images/mine/8g7i) | Crystal Structure of FosB from Bacillus cereus with Zinc and Sulfate | Descriptor: | FORMIC ACID, GLYCEROL, MAGNESIUM ION, ... | Authors: | Travis, S, Pang, A.H, Tsodikov, O.V, Garneau-Tsodikova, S, Thompson, M.K. | Deposit date: | 2023-02-16 | Release date: | 2023-06-14 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Identification and analysis of small molecule inhibitors of FosB from Staphylococcus aureus. Rsc Med Chem, 14, 2023
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8D1R
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![BU of 8d1r by Molmil](/molmil-images/mine/8d1r) | Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with inhibitor SGT520 | Descriptor: | 1-{3-[(4-chlorophenyl)methoxy]phenyl}methanamine, GLYCEROL, N-acetyltransferase Eis | Authors: | Pang, A.H, Punetha, A, Garneau-Tsodikova, S, Tsodikov, O.V. | Deposit date: | 2022-05-27 | Release date: | 2022-09-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Discovery of substituted benzyloxy-benzylamine inhibitors of acetyltransferase Eis and their anti-mycobacterial activity. Eur.J.Med.Chem., 242, 2022
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8D25
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![BU of 8d25 by Molmil](/molmil-images/mine/8d25) | Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with inhibitor SGT530 | Descriptor: | 1-{2-[(3-chlorophenyl)methoxy]phenyl}-N-[(pyridin-4-yl)methyl]methanamine, GLYCEROL, N-acetyltransferase Eis | Authors: | Pang, A.H, Punetha, A, Garneau-Tsodikova, S, Tsodikov, O.V. | Deposit date: | 2022-05-27 | Release date: | 2022-09-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Discovery of substituted benzyloxy-benzylamine inhibitors of acetyltransferase Eis and their anti-mycobacterial activity. Eur.J.Med.Chem., 242, 2022
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8D23
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![BU of 8d23 by Molmil](/molmil-images/mine/8d23) | Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with inhibitor SGT529 | Descriptor: | 1-{2-[(3-chlorophenyl)methoxy]phenyl}-N-[(pyridin-3-yl)methyl]methanamine, GLYCEROL, N-acetyltransferase Eis | Authors: | Pang, A.H, Punetha, A, Garneau-Tsodikova, S, Tsodikov, O.V. | Deposit date: | 2022-05-27 | Release date: | 2022-09-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Discovery of substituted benzyloxy-benzylamine inhibitors of acetyltransferase Eis and their anti-mycobacterial activity. Eur.J.Med.Chem., 242, 2022
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