Crystal structure of MtmC in complex with SAM and TDP

Summary for 4RVG

Related1RV9 4RVD 4RVF 4RVH
DescriptorD-mycarose 3-C-methyltransferase, ZINC ION, THYMIDINE-5'-DIPHOSPHATE, ... (6 entities in total)
Functional Keywordsc-methyltransferase, tdp-4-keto-d-olivose, transferase
Biological sourceStreptomyces argillaceus
Total number of polymer chains1
Total molecular weight47850.24
Tsodikov, O.V.,Hou, C.,Chen, J.-M.,Rohr, J. (deposition date: 2014-11-26, release date: 2015-01-28, Last modification date: 2015-05-06)
Primary citation
Chen, J.M.,Hou, C.,Wang, G.,Tsodikov, O.V.,Rohr, J.
Structural Insight into MtmC, a Bifunctional Ketoreductase-Methyltransferase Involved in the Assembly of the Mithramycin Trisaccharide Chain.
Biochemistry, 54:2481-2489, 2015
PubMed: 25587924 (PDB entries with the same primary citation)
DOI: 10.1021/bi501462g
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.240203.8%2.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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