4ZGI
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![BU of 4zgi by Molmil](/molmil-images/mine/4zgi) | Structure of Truncated Human TIFA | 分子名称: | TRAF-interacting protein with FHA domain-containing protein A | 著者 | Weng, J.H, Wei, T.Y.W, Hsieh, Y.C, Huang, C.C.F, Wu, P.Y.G, Chen, E.S.W, Huang, K.F, Chen, C.J, Tsai, M.D. | 登録日 | 2015-04-23 | 公開日 | 2015-10-14 | 最終更新日 | 2015-10-28 | 実験手法 | X-RAY DIFFRACTION (2.701 Å) | 主引用文献 | Uncovering the Mechanism of Forkhead-Associated Domain-Mediated TIFA Oligomerization That Plays a Central Role in Immune Responses. Biochemistry, 54, 2015
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2VAN
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![BU of 2van by Molmil](/molmil-images/mine/2van) | Nucleotidyl Transfer Mechanism of Mismatched dNTP Incorporation by DNA Polymerase b by Structural and Kinetic Analyses | 分子名称: | DNA POLYMERSE BETA | 著者 | Chan, H, Chou, C, Tang, K, Niebuhr, M, Tung, C, Tsai, M. | 登録日 | 2007-09-03 | 公開日 | 2008-04-15 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Mismatched Dntp Incorporation by DNA Polymerase Beta Does not Proceed Via Globally Different Conformational Pathways. Nucleic Acids Res., 36, 2008
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1T6M
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![BU of 1t6m by Molmil](/molmil-images/mine/1t6m) | X-ray Structure of the R70D PI-PLC enzyme: Insight into the role of calcium and surrounding amino acids on active site geometry and catalysis. | 分子名称: | 1-phosphatidylinositol phosphodiesterase, CALCIUM ION | 著者 | Apiyo, D, Zhao, L, Tsai, M.-D, Selby, T.L. | 登録日 | 2004-05-06 | 公開日 | 2005-08-16 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.107 Å) | 主引用文献 | X-ray Structure of the R69D Phosphatidylinositol-Specific Phospholipase C Enzyme: Insight into the Role of Calcium and Surrounding Amino Acids in Active Site Geometry and Catalysis. Biochemistry, 44, 2005
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5YEQ
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![BU of 5yeq by Molmil](/molmil-images/mine/5yeq) | The structure of Sac-KARI protein | 分子名称: | 1,2-ETHANEDIOL, Ketol-acid reductoisomerase (NADP(+)), MAGNESIUM ION, ... | 著者 | Ko, T.P, Chen, C.Y, Lin, K.F, Lin, B.L, Huang, C.H, Chiang, C.H, Horng, J.C, Tsai, M.D. | 登録日 | 2017-09-19 | 公開日 | 2018-07-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | NADH/NADPH bi-cofactor-utilizing and thermoactive ketol-acid reductoisomerase from Sulfolobus acidocaldarius Sci Rep, 8, 2018
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6LY7
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![BU of 6ly7 by Molmil](/molmil-images/mine/6ly7) | PylRS C-terminus domain mutant bound with 1-Formyl-L-tryptophan and AMPNP | 分子名称: | MAGNESIUM ION, N1-FORMYL-TRYPTOPHAN, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Weng, J.H, Tsai, M.D, Wang, Y.S. | 登録日 | 2020-02-13 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.09447265 Å) | 主引用文献 | Probing the Active Site of Deubiquitinase USP30 with Noncanonical Tryptophan Analogues. Biochemistry, 59, 2020
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6JD1
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![BU of 6jd1 by Molmil](/molmil-images/mine/6jd1) | Cryo-EM Structure of Sulfolobus solfataricus ketol-acid reductoisomerase (Sso-KARI) in complex with Mg2+, NADH, and CPD at pH7.5 | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, MAGNESIUM ION, Putative ketol-acid reductoisomerase 2, ... | 著者 | Chen, C.Y, Chang, Y.C, Lin, K.F, Huang, C.H, Lin, B.L, Ko, T.P, Hsieh, D.L, Tsai, M.D. | 登録日 | 2019-01-30 | 公開日 | 2019-04-17 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | 主引用文献 | Use of Cryo-EM To Uncover Structural Bases of pH Effect and Cofactor Bispecificity of Ketol-Acid Reductoisomerase. J. Am. Chem. Soc., 141, 2019
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6LYA
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![BU of 6lya by Molmil](/molmil-images/mine/6lya) | PylRS C-terminus domain mutant bound with 1-Methyl-L-tryptophan and AMPNP | 分子名称: | 1,2-ETHANEDIOL, 1-Methyl-L-tryptophan, MAGNESIUM ION, ... | 著者 | Weng, J.H, Tsai, M.D, Wang, Y.S. | 登録日 | 2020-02-13 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.590702 Å) | 主引用文献 | Probing the Active Site of Deubiquitinase USP30 with Noncanonical Tryptophan Analogues. Biochemistry, 59, 2020
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6LYB
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![BU of 6lyb by Molmil](/molmil-images/mine/6lyb) | PylRS C-terminus domain mutant in complex with 3-Benzothienyl-D-alanine and AMPNP | 分子名称: | (2R)-2-azanyl-3-(1-benzothiophen-3-yl)propanoic acid, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Weng, J.H, Tsai, M.D, Wang, Y.S. | 登録日 | 2020-02-13 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.90366471 Å) | 主引用文献 | Probing the Active Site of Deubiquitinase USP30 with Noncanonical Tryptophan Analogues. Biochemistry, 59, 2020
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6JD2
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![BU of 6jd2 by Molmil](/molmil-images/mine/6jd2) | Crystal structure of Sulfolobus solfataricus ketol-acid reductoisomerase (Sso-KARI) in complex with Mg2+ at pH8.5 | 分子名称: | BETA-MERCAPTOETHANOL, MAGNESIUM ION, Putative ketol-acid reductoisomerase 2 | 著者 | Chen, C.Y, Chang, Y.C, Lin, K.F, Huang, C.H, Lin, B.L, Ko, T.P, Hsieh, D.L, Tsai, M.D. | 登録日 | 2019-01-30 | 公開日 | 2019-08-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Use of Cryo-EM To Uncover Structural Bases of pH Effect and Cofactor Bispecificity of Ketol-Acid Reductoisomerase. J.Am.Chem.Soc., 141, 2019
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6LY3
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![BU of 6ly3 by Molmil](/molmil-images/mine/6ly3) | PylRS C-terminus domain mutant bound with 3-Benzothienyl-L-alanine and AMPNP | 分子名称: | 3-(1-benzothiophen-3-yl)-L-alanine, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Weng, J.H, Tsai, M.D, Wang, Y.S. | 登録日 | 2020-02-13 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.89590144 Å) | 主引用文献 | Probing the Active Site of Deubiquitinase USP30 with Noncanonical Tryptophan Analogues. Biochemistry, 59, 2020
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6JCW
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![BU of 6jcw by Molmil](/molmil-images/mine/6jcw) | Cryo-EM Structure of Sulfolobus solfataricus ketol-acid reductoisomerase (Sso-KARI) with Mg2+ at pH8.5 | 分子名称: | MAGNESIUM ION, ketol-acid reductoisomerase | 著者 | Chen, C.Y, Chang, Y.C, Lin, K.F, Huang, C.H, Lin, B.L, Ko, T.P, Hsieh, D.L, Tsai, M.D. | 登録日 | 2019-01-30 | 公開日 | 2019-04-17 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | 主引用文献 | Use of Cryo-EM To Uncover Structural Bases of pH Effect and Cofactor Bispecificity of Ketol-Acid Reductoisomerase. J. Am. Chem. Soc., 141, 2019
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6JCV
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![BU of 6jcv by Molmil](/molmil-images/mine/6jcv) | Cryo-EM structure of Sulfolobus solfataricus ketol-acid reductoisomerase (Sso-KARI) with Mg2+ at pH7.5 | 分子名称: | MAGNESIUM ION, Putative ketol-acid reductoisomerase 2 | 著者 | Chen, C.Y, Chang, Y.C, Lin, K.F, Huang, C.H, Lin, B.L, Ko, T.P, Hsieh, D.L, Tsai, M.D. | 登録日 | 2019-01-30 | 公開日 | 2019-04-17 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Use of Cryo-EM To Uncover Structural Bases of pH Effect and Cofactor Bispecificity of Ketol-Acid Reductoisomerase. J. Am. Chem. Soc., 141, 2019
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6JCZ
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![BU of 6jcz by Molmil](/molmil-images/mine/6jcz) | Cryo-EM Structure of Sulfolobus solfataricus ketol-acid reductoisomerase (Sso-KARI) in complex with Mg2+, NADPH, and CPD at pH7.5 | 分子名称: | MAGNESIUM ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative ketol-acid reductoisomerase 2, ... | 著者 | Chen, C.Y, Chang, Y.C, Lin, K.F, Huang, C.H, Lin, B.L, Ko, T.P, Hsieh, D.L, Tsai, M.D. | 登録日 | 2019-01-30 | 公開日 | 2019-04-17 | 最終更新日 | 2019-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | Use of Cryo-EM To Uncover Structural Bases of pH Effect and Cofactor Bispecificity of Ketol-Acid Reductoisomerase. J. Am. Chem. Soc., 141, 2019
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6LY6
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![BU of 6ly6 by Molmil](/molmil-images/mine/6ly6) | PylRS C-terminus domain mutant bound with 3-(1-Naphthyl)-L-alanine and AMPNP | 分子名称: | MAGNESIUM ION, NAPHTHALEN-2-YL-3-ALANINE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Weng, J.H, Tsai, M.D, Wang, Y.S. | 登録日 | 2020-02-13 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5001328 Å) | 主引用文献 | Probing the Active Site of Deubiquitinase USP30 with Noncanonical Tryptophan Analogues. Biochemistry, 59, 2020
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6IQO
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![BU of 6iqo by Molmil](/molmil-images/mine/6iqo) | Se-Met L45M Programmed Cell Death 5 protein from Sulfolobus solfataricus | 分子名称: | DNA-binding protein SSO0352, NONAETHYLENE GLYCOL | 著者 | Chen, C.Y, Lin, K.F, Hsu, C.Y, Tsai, M.J. | 登録日 | 2018-11-08 | 公開日 | 2019-02-20 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Crystal structure of the programmed cell death 5 protein from Sulfolobus solfataricus. Acta Crystallogr F Struct Biol Commun, 75, 2019
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1TR4
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![BU of 1tr4 by Molmil](/molmil-images/mine/1tr4) | Solution structure of human oncogenic protein gankyrin | 分子名称: | 26S proteasome non-ATPase regulatory subunit 10 | 著者 | Yuan, C, Li, J, Mahajan, A, Poi, M.J, Byeon, I.J, Tsai, M.D. | 登録日 | 2004-06-19 | 公開日 | 2004-11-16 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the human oncogenic protein gankyrin containing seven ankyrin repeats and analysis of its structure--function relationship. Biochemistry, 43, 2004
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6KPE
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![BU of 6kpe by Molmil](/molmil-images/mine/6kpe) | 343 K cryoEM structure of Sso-KARI in complex with Mg2+ | 分子名称: | Ketol-acid reductoisomerase, MAGNESIUM ION | 著者 | Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D. | 登録日 | 2019-08-15 | 公開日 | 2020-03-25 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions. J.Am.Chem.Soc., 141, 2019
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6KQJ
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![BU of 6kqj by Molmil](/molmil-images/mine/6kqj) | 309 K cryoEM structure of Sso-KARI in complex with Mg2+, NADH and CPD | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Ketol-acid reductoisomerase, MAGNESIUM ION, ... | 著者 | Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D. | 登録日 | 2019-08-18 | 公開日 | 2020-03-25 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.54 Å) | 主引用文献 | Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions. J.Am.Chem.Soc., 141, 2019
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6KOU
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![BU of 6kou by Molmil](/molmil-images/mine/6kou) | 277 K cryoEM structure of Sso-KARI in complex with magnesium ions | 分子名称: | Ketol-acid reductoisomerase, MAGNESIUM ION | 著者 | Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D. | 登録日 | 2019-08-13 | 公開日 | 2020-03-25 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.43 Å) | 主引用文献 | Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions. J.Am.Chem.Soc., 141, 2019
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6KQ4
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![BU of 6kq4 by Molmil](/molmil-images/mine/6kq4) | 323 K cryoEM structure of Sso-KARI in complex with Mg2+ | 分子名称: | Ketol-acid reductoisomerase, MAGNESIUM ION | 著者 | Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D. | 登録日 | 2019-08-16 | 公開日 | 2020-03-25 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions. J.Am.Chem.Soc., 141, 2019
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6KPI
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![BU of 6kpi by Molmil](/molmil-images/mine/6kpi) | 298 K cryoEM structure of Sso-KARI in complex with Mg2+ | 分子名称: | Ketol-acid reductoisomerase, MAGNESIUM ION | 著者 | Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D. | 登録日 | 2019-08-15 | 公開日 | 2020-03-25 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.43 Å) | 主引用文献 | Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions. J.Am.Chem.Soc., 141, 2019
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6KPJ
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![BU of 6kpj by Molmil](/molmil-images/mine/6kpj) | 298 K cryoEM structure of Sso-KARI in complex with Mg2+, NADH and CPD | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Ketol-acid reductoisomerase, MAGNESIUM ION, ... | 著者 | Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D. | 登録日 | 2019-08-15 | 公開日 | 2020-03-25 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.56 Å) | 主引用文献 | Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions. J.Am.Chem.Soc., 141, 2019
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6KQ8
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![BU of 6kq8 by Molmil](/molmil-images/mine/6kq8) | 328 K cryoEM structure of Sso-KARI in complex with Mg2+ | 分子名称: | Ketol-acid reductoisomerase, MAGNESIUM ION | 著者 | Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D. | 登録日 | 2019-08-16 | 公開日 | 2020-03-25 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions. J.Am.Chem.Soc., 141, 2019
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6KPA
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![BU of 6kpa by Molmil](/molmil-images/mine/6kpa) | 277 K cryoEM structure of Sso-KARI in complex with Mg2+, NADH and CPD | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Ketol-acid reductoisomerase, MAGNESIUM ION, ... | 著者 | Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D. | 登録日 | 2019-08-15 | 公開日 | 2020-03-25 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | 主引用文献 | Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions. J.Am.Chem.Soc., 141, 2019
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6KPH
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![BU of 6kph by Molmil](/molmil-images/mine/6kph) | 343 K cryoEM structure of Sso-KARI in complex with Mg2+, NADH and CPD | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Ketol-acid reductoisomerase, MAGNESIUM ION, ... | 著者 | Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D. | 登録日 | 2019-08-15 | 公開日 | 2020-03-25 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.41 Å) | 主引用文献 | Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions. J.Am.Chem.Soc., 141, 2019
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