6Z9U
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![BU of 6z9u by Molmil](/molmil-images/mine/6z9u) | Crystal structure of a TSEN15-34 heterodimer. | Descriptor: | GLYCEROL, tRNA-splicing endonuclease subunit Sen15, tRNA-splicing endonuclease subunit Sen34 | Authors: | Trowitzsch, S, Sekulovski, S. | Deposit date: | 2020-06-04 | Release date: | 2021-06-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.10001779 Å) | Cite: | Assembly defects of human tRNA splicing endonuclease contribute to impaired pre-tRNA processing in pontocerebellar hypoplasia. Nat Commun, 12, 2021
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6ENY
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![BU of 6eny by Molmil](/molmil-images/mine/6eny) | Structure of the human PLC editing module | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Calreticulin, ... | Authors: | Trowitzsch, S, Januliene, D, Blees, A, Moeller, A, Tampe, R. | Deposit date: | 2017-10-07 | Release date: | 2017-11-29 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (5.8 Å) | Cite: | Structure of the human MHC-I peptide-loading complex. Nature, 551, 2017
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4WV4
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![BU of 4wv4 by Molmil](/molmil-images/mine/4wv4) | Heterodimer of TAF8/TAF10 | Descriptor: | CHLORIDE ION, GLYCEROL, Transcription initiation factor TFIID subunit 10, ... | Authors: | Trowitzsch, S. | Deposit date: | 2014-11-04 | Release date: | 2015-01-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.909 Å) | Cite: | Cytoplasmic TAF2-TAF8-TAF10 complex provides evidence for nuclear holo-TFIID assembly from preformed submodules. Nat Commun, 6, 2015
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4WV6
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![BU of 4wv6 by Molmil](/molmil-images/mine/4wv6) | Heterodimer of Importin alpha 1 with nuclear localization signal of TAF8 | Descriptor: | 1,2-ETHANEDIOL, Importin subunit alpha-1, Transcription initiation factor TFIID subunit 8 | Authors: | Trowitzsch, S. | Deposit date: | 2014-11-04 | Release date: | 2015-01-28 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Cytoplasmic TAF2-TAF8-TAF10 complex provides evidence for nuclear holo-TFIID assembly from preformed submodules. Nat Commun, 6, 2015
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2POX
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![BU of 2pox by Molmil](/molmil-images/mine/2pox) | |
3ELV
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![BU of 3elv by Molmil](/molmil-images/mine/3elv) | Crystal Structure of Full-Length Yeast Pml1p | Descriptor: | Pre-mRNA leakage protein 1, SULFATE ION | Authors: | Trowitzsch, S, Weber, G, L hrmann, R, Wahl, M.C. | Deposit date: | 2008-09-23 | Release date: | 2009-02-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of the Pml1p subunit of the yeast precursor mRNA retention and splicing complex. J.Mol.Biol., 385, 2009
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3ELS
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![BU of 3els by Molmil](/molmil-images/mine/3els) | Crystal Structure of Yeast Pml1p, Residues 51-204 | Descriptor: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | Authors: | Trowitzsch, S, Weber, G, Luehrmann, R, Wahl, M.C. | Deposit date: | 2008-09-23 | Release date: | 2009-02-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the Pml1p subunit of the yeast precursor mRNA retention and splicing complex. J.Mol.Biol., 385, 2009
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3LSA
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![BU of 3lsa by Molmil](/molmil-images/mine/3lsa) | Padron0.9-OFF (non-fluorescent state) | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Padron0.9, ... | Authors: | Brakemann, T, Weber, G, Trowitzsch, S, Wahl, M.C, Jakobs, S. | Deposit date: | 2010-02-12 | Release date: | 2010-03-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Molecular basis of the light-driven switching of the photochromic fluorescent protein Padron. J.Biol.Chem., 285, 2010
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7ZRZ
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![BU of 7zrz by Molmil](/molmil-images/mine/7zrz) | |
3LS3
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![BU of 3ls3 by Molmil](/molmil-images/mine/3ls3) | Padron0.9-ON (fluorescent state) | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Padron0.9, ... | Authors: | Brakemann, T, Weber, G, Trowitzsch, S, Wahl, M.C, Jakobs, S. | Deposit date: | 2010-02-12 | Release date: | 2010-03-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Molecular basis of the light-driven switching of the photochromic fluorescent protein Padron. J.Biol.Chem., 285, 2010
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8OMR
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![BU of 8omr by Molmil](/molmil-images/mine/8omr) | Human tRNA guanine transglycosylase (TGT) bound to tRNAAsp | Descriptor: | 9-DEAZAGUANINE, Queuine tRNA-ribosyltransferase accessory subunit 2, Queuine tRNA-ribosyltransferase catalytic subunit 1, ... | Authors: | Sievers, K, Neumann, P, Susac, L, Trowitzsch, S, Tampe, R, Ficner, R. | Deposit date: | 2023-03-31 | Release date: | 2023-12-20 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural and functional insights into tRNA recognition by human tRNA guanine transglycosylase. Structure, 32, 2024
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2IOV
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![BU of 2iov by Molmil](/molmil-images/mine/2iov) | Bright-state structure of the reversibly switchable fluorescent protein Dronpa | Descriptor: | Fluorescent protein Dronpa | Authors: | Stiel, A.C, Trowitzsch, S, Weber, G, Andresen, M, Eggeling, C, Hell, S.W, Jakobs, S, Wahl, M.C. | Deposit date: | 2006-10-11 | Release date: | 2006-12-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | 1.8 A bright-state structure of the reversibly switchable fluorescent protein Dronpa guides the generation of fast switching variants Biochem.J., 402, 2007
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5LL6
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![BU of 5ll6 by Molmil](/molmil-images/mine/5ll6) | Structure of the 40S ABCE1 post-splitting complex in ribosome recycling and translation initiation | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | Authors: | Heuer, A, Gerovac, M, Schmidt, C, Trowitzsch, S, Preis, A, Koetter, P, Berninghausen, O, Becker, T, Beckmann, R, Tampe, R. | Deposit date: | 2016-07-26 | Release date: | 2017-04-12 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structure of the 40S-ABCE1 post-splitting complex in ribosome recycling and translation initiation. Nat. Struct. Mol. Biol., 24, 2017
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3PGW
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![BU of 3pgw by Molmil](/molmil-images/mine/3pgw) | Crystal structure of human U1 snRNP | Descriptor: | DNA 5'-D(*AP*GP*GP*TP*AP*AP*GP*TP*A)-3', Sm B, Sm G, ... | Authors: | Weber, G, Trowitzsch, S, Kastner, B, Luehrmann, R, Wahl, M.C. | Deposit date: | 2010-11-02 | Release date: | 2010-12-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (4.4 Å) | Cite: | Functional organization of the Sm core in the crystal structure of human U1 snRNP. Embo J., 29, 2010
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2MKC
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![BU of 2mkc by Molmil](/molmil-images/mine/2mkc) | Cooperative Structure of the Heterotrimeric pre-mRNA Retention and Splicing Complex | Descriptor: | Pre-mRNA leakage protein 1, Pre-mRNA-splicing factor CWC26, U2 snRNP component IST3 | Authors: | Wysoczanski, P, Schneider, C, Xiang, S, Munari, F, Trowitzsch, S, Wahl, M.C, Luhrmann, R, Becker, S, Zweckstetter, M. | Deposit date: | 2014-02-04 | Release date: | 2014-09-03 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Cooperative structure of the heterotrimeric pre-mRNA retention and splicing complex. Nat.Struct.Mol.Biol., 21, 2014
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7QNG
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![BU of 7qng by Molmil](/molmil-images/mine/7qng) | Structure of a MHC I-Tapasin-ERp57 complex | Descriptor: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | Authors: | Mueller, I.K, Thomas, C, Trowitzsch, S, Tampe, R. | Deposit date: | 2021-12-20 | Release date: | 2022-09-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of an MHC I-tapasin-ERp57 editing complex defines chaperone promiscuity. Nat Commun, 13, 2022
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7QPD
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![BU of 7qpd by Molmil](/molmil-images/mine/7qpd) | Structure of the human MHC I peptide-loading complex editing module | Descriptor: | Beta-2-microglobulin, Calreticulin, HLA class I histocompatibility antigen, ... | Authors: | Domnick, A, Susac, L, Trowitzsch, S, Thomas, C, Tampe, R. | Deposit date: | 2022-01-03 | Release date: | 2022-07-20 | Last modified: | 2022-08-24 | Method: | ELECTRON MICROSCOPY (3.73 Å) | Cite: | Molecular basis of MHC I quality control in the peptide loading complex. Nat Commun, 13, 2022
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2A50
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![BU of 2a50 by Molmil](/molmil-images/mine/2a50) | fluorescent protein asFP595, wt, off-state | Descriptor: | GFP-like non-fluorescent chromoprotein FP595 chain 1, GFP-like non-fluorescent chromoprotein FP595 chain 2 | Authors: | Andresen, M, Wahl, M.C, Stiel, A.C, Graeter, F, Schaefer, L, Trowitzsch, S, Weber, G, Eggeling, C, Grubmueller, H, Hell, S.W, Jakobs, S. | Deposit date: | 2005-06-30 | Release date: | 2005-08-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structure and mechanism of the reversible photoswitch of a fluorescent protein Proc.Natl.Acad.Sci.Usa, 102, 2005
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2A54
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![BU of 2a54 by Molmil](/molmil-images/mine/2a54) | fluorescent protein asFP595, A143S, on-state, 1min irradiation | Descriptor: | CHLORIDE ION, GFP-like non-fluorescent chromoprotein FP595 chain 1, GFP-like non-fluorescent chromoprotein FP595 chain 2 | Authors: | Andresen, M, Wahl, M.C, Stiel, A.C, Graeter, F, Schaefer, L, Trowitzsch, S, Weber, G, Eggeling, C, Grubmueller, H, Hell, S.W, Jakobs, S. | Deposit date: | 2005-06-30 | Release date: | 2005-08-16 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure and mechanism of the reversible photoswitch of a fluorescent protein Proc.Natl.Acad.Sci.Usa, 102, 2005
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2A52
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![BU of 2a52 by Molmil](/molmil-images/mine/2a52) | fluorescent protein asFP595, S158V, on-state | Descriptor: | GFP-like non-fluorescent chromoprotein FP595 chain 1, GFP-like non-fluorescent chromoprotein FP595 chain 2 | Authors: | Andresen, M, Wahl, M.C, Stiel, A.C, Graeter, F, Schaefer, L, Trowitzsch, S, Weber, G, Eggeling, C, Grubmueller, H, Hell, S.W, Jakobs, S. | Deposit date: | 2005-06-30 | Release date: | 2005-08-16 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure and mechanism of the reversible photoswitch of a fluorescent protein Proc.Natl.Acad.Sci.Usa, 102, 2005
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2A53
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![BU of 2a53 by Molmil](/molmil-images/mine/2a53) | fluorescent protein asFP595, A143S, off-state | Descriptor: | CHLORIDE ION, GFP-like non-fluorescent chromoprotein FP595 chain 1, GFP-like non-fluorescent chromoprotein FP595 chain 2 | Authors: | Andresen, M, Wahl, M.C, Stiel, A.C, Graeter, F, Schaefer, L, Trowitzsch, S, Weber, G, Eggeling, C, Grubmueller, H, Hell, S.W, Jakobs, S. | Deposit date: | 2005-06-30 | Release date: | 2005-08-16 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure and mechanism of the reversible photoswitch of a fluorescent protein Proc.Natl.Acad.Sci.Usa, 102, 2005
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2A56
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![BU of 2a56 by Molmil](/molmil-images/mine/2a56) | fluorescent protein asFP595, A143S, on-state, 5min irradiation | Descriptor: | GFP-like non-fluorescent chromoprotein FP595 chain 1, GFP-like non-fluorescent chromoprotein FP595 chain 2 | Authors: | Andresen, M, Wahl, M.C, Stiel, A.C, Graeter, F, Schaefer, L, Trowitzsch, S, Weber, G, Eggeling, C, Grubmueller, H, Hell, S.W, Jakobs, S. | Deposit date: | 2005-06-30 | Release date: | 2005-08-16 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and mechanism of the reversible photoswitch of a fluorescent protein Proc.Natl.Acad.Sci.Usa, 102, 2005
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