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PDB: 61 results

6OAO
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BU of 6oao by Molmil
Structure of DBP in complex with human neutralizing antibody 092096
Descriptor: Antibody 092096 single chain variable fragment, Duffy binding surface protein region II, SULFATE ION
Authors:Urusova, D, Tolia, N.H.
Deposit date:2019-03-18
Release date:2019-06-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.497 Å)
Cite:Structural basis for neutralization of Plasmodium vivax by naturally acquired human antibodies that target DBP.
Nat Microbiol, 4, 2019
6WG9
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BU of 6wg9 by Molmil
Crystal structure of tetracycline destructase Tet(X7)
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Tetracycline destructase Tet(X7)
Authors:Kumar, H, Tolia, N.H.
Deposit date:2020-04-05
Release date:2021-02-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Tetracycline-inactivating enzymes from environmental, human commensal, and pathogenic bacteria cause broad-spectrum tetracycline resistance.
Commun Biol, 3, 2020
7U9E
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BU of 7u9e by Molmil
Pfs230 D1 domain in complex with 230AL-26
Descriptor: 230AL-26, Gametocyte surface protein P230, LMIV230-01
Authors:Tang, W.K, Tolia, N.H.
Deposit date:2022-03-10
Release date:2023-02-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
5F3J
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Crystal structure of DBP in complex with inhibitory monoclonal antibody 2D10
Descriptor: Antibody 2D10 single chain variable fragment, Duffy receptor
Authors:Chen, E, Salinas, N.D, Tolia, N.H.
Deposit date:2015-12-02
Release date:2016-05-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (4.001 Å)
Cite:Broadly neutralizing epitopes in the Plasmodium vivax vaccine candidate Duffy Binding Protein.
Proc.Natl.Acad.Sci.USA, 113, 2016
8DCC
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BU of 8dcc by Molmil
SARS-CoV-2 Receptor-Binding Domain SPEEDesign Immunogen 3 Bound to P2B-2F6 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, P2B-2F6 Fab heavy chain, P2B-2F6 Fab light chain, ...
Authors:Dickey, T.D, Tolia, N.H.
Deposit date:2022-06-16
Release date:2022-07-06
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Design of the SARS-CoV-2 RBD vaccine antigen improves neutralizing antibody response.
Sci Adv, 8, 2022
4GF2
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BU of 4gf2 by Molmil
Crystal structure of Plasmodium falciparum Erythrocyte Binding Antigen 140 (PfEBA-140/BAEBL)
Descriptor: Erythrocyte binding antigen 140, GLYCEROL
Authors:Lin, D.H, Malpede, B.M, Batchelor, J.D, Tolia, N.H.
Deposit date:2012-08-02
Release date:2012-09-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal and Solution Structures of Plasmodium falciparum Erythrocyte-binding Antigen 140 Reveal Determinants of Receptor Specificity during Erythrocyte Invasion.
J.Biol.Chem., 287, 2012
4QEX
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BU of 4qex by Molmil
Crystal structure of PfEBA-175 RII in complex with a Fab fragment from inhibitory antibody R217
Descriptor: Antibody Heavy Chain, Antibody Light Chain, Erythrocyte-binding antigen-175
Authors:Chen, E, Paing, M.M, Salinas, N, Sim, B.K, Tolia, N.H.
Deposit date:2014-05-19
Release date:2014-06-04
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structural and Functional Basis for Inhibition of Erythrocyte Invasion by Antibodies that Target Plasmodium falciparum EBA-175.
Plos Pathog., 9, 2013
7UFW
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BU of 7ufw by Molmil
Pfs230 D1D2 in complex with LMIV230-01
Descriptor: Gametocyte surface protein P230, LMIV230-01
Authors:Tang, W.K, Tolia, N.H.
Deposit date:2022-03-23
Release date:2023-02-15
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
7UA8
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BU of 7ua8 by Molmil
Pfs230 D1 domain in complex with 230AL-20
Descriptor: 230Al-20, Gametocyte surface protein P230
Authors:Tang, W.K, Tolia, N.H.
Deposit date:2022-03-11
Release date:2023-02-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
7UA2
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BU of 7ua2 by Molmil
Pfs230 D1 domain in complex with 230AL-18
Descriptor: 230AL-18, Gametocyte surface protein P230, LMIV230-01
Authors:Tang, W.K, Tolia, N.H.
Deposit date:2022-03-11
Release date:2023-02-15
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
7UCQ
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BU of 7ucq by Molmil
Pfs230 D1 domain in complex with 230AS-18
Descriptor: 230AS-18, Gametocyte surface protein P230
Authors:Tang, W.K, Tolia, N.H.
Deposit date:2022-03-17
Release date:2023-02-15
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
7UI1
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BU of 7ui1 by Molmil
Pfs230 D1D2 domain in complex with 230AL-37
Descriptor: 230AL-37, Gametocyte surface protein P230, SULFATE ION
Authors:Tang, W.K, Tolia, N.H.
Deposit date:2022-03-28
Release date:2023-02-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
7UC8
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BU of 7uc8 by Molmil
Pfs230 D1 domain in complex with 230AS-73
Descriptor: 230AS-73, Gametocyte surface protein P230, SODIUM ION
Authors:Tang, W.K, Tolia, N.H.
Deposit date:2022-03-16
Release date:2023-02-15
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
4YFS
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BU of 4yfs by Molmil
Structure of the synthetic Duffy Binding Protein (DBP) antigen DEKnull relevant for malaria vaccine design
Descriptor: Duffy receptor
Authors:Chen, E, Tolia, N.H.
Deposit date:2015-02-25
Release date:2015-03-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Analysis of the Synthetic Duffy Binding Protein (DBP) Antigen DEKnull Relevant for Plasmodium vivax Malaria Vaccine Design.
Plos Negl Trop Dis, 9, 2015
4ZEW
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BU of 4zew by Molmil
Crystal structure of PfHAD1 in complex with glucose-6-phosphate
Descriptor: 6-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Park, J, Tolia, N.H.
Deposit date:2015-04-20
Release date:2015-09-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Cap-domain closure enables diverse substrate recognition by the C2-type haloacid dehalogenase-like sugar phosphatase Plasmodium falciparum HAD1.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4ZEX
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BU of 4zex by Molmil
Crystal structure of PfHAD1 in complex with glyceraldehyde-3-phosphate
Descriptor: GLYCERALDEHYDE-3-PHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Park, J, Tolia, N.H.
Deposit date:2015-04-20
Release date:2015-09-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cap-domain closure enables diverse substrate recognition by the C2-type haloacid dehalogenase-like sugar phosphatase Plasmodium falciparum HAD1.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
7U9W
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BU of 7u9w by Molmil
Pfs230 D1 domain in complex with 230AS-88
Descriptor: 230AS-88, Gametocyte surface protein P230
Authors:Tang, W.K, Tolia, N.H.
Deposit date:2022-03-11
Release date:2023-02-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
7UBS
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BU of 7ubs by Molmil
Pfs230 D1 domain in complex with 230AS-26
Descriptor: 230AS-26, Gametocyte surface protein P230
Authors:Tang, W.K, Tolia, N.H.
Deposit date:2022-03-15
Release date:2023-02-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
4ZEV
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BU of 4zev by Molmil
Crystal structure of PfHAD1 in complex with mannose-6-phosphate
Descriptor: 6-O-phosphono-alpha-D-mannopyranose, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Park, J, Tolia, N.H.
Deposit date:2015-04-20
Release date:2015-09-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Cap-domain closure enables diverse substrate recognition by the C2-type haloacid dehalogenase-like sugar phosphatase Plasmodium falciparum HAD1.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
1Z25
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BU of 1z25 by Molmil
Structure of P.furiosus Argonaute with bound Mn2+
Descriptor: Argonaute, MANGANESE (II) ION
Authors:Rivas, F.V, Tolia, N.H, Song, J.J, Aragon, J.P, Liu, J, Hannon, G.J, Joshua-Tor, L.
Deposit date:2005-03-07
Release date:2005-04-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Purified Argonaute2 and an siRNA form recombinant human RISC.
Nat.Struct.Mol.Biol., 12, 2005
1Z26
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BU of 1z26 by Molmil
Structure of Pyrococcus furiosus Argonaute with bound tungstate
Descriptor: Argonaute, TUNGSTATE(VI)ION
Authors:Rivas, F.V, Tolia, N.H, Song, J.J, Aragon, J.P, Liu, J, Hannon, G.J, Joshua-Tor, L.
Deposit date:2005-03-07
Release date:2005-04-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Purified Argonaute2 and an siRNA form recombinant human RISC.
Nat.Struct.Mol.Biol., 12, 2005
8DCE
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BU of 8dce by Molmil
SARS-CoV-2 Receptor-Binding Domain SPEEDesign Immunogen 1 Bound to C144 scFv
Descriptor: C144 scFv, Spike protein S1
Authors:Tang, W.K, Tolia, N.H.
Deposit date:2022-06-16
Release date:2022-06-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design of the SARS-CoV-2 RBD vaccine antigen improves neutralizing antibody response.
Sci Adv, 8, 2022
8DFG
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BU of 8dfg by Molmil
Crystal structure of potently neutralizing human monoclonal antibody 42D6 Fab in complex with MSP1-19
Descriptor: 42D6 Fab Heavy Chain, 42D6 Fab Light Chain, Merozoite surface protein 1
Authors:Patel, P.N, Tang, W.K, Tolia, N.H.
Deposit date:2022-06-22
Release date:2022-10-12
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion.
Nat Commun, 13, 2022
8DFH
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BU of 8dfh by Molmil
Crystal structure of non-neutralizing / interfering human monoclonal antibody 42C3 Fab in complex with MSP1-19
Descriptor: 42C3 Fab Heavy Chain, 42C3 Fab Light Chain, Merozoite surface protein 1
Authors:Patel, P.N, Tang, W.K, Tolia, N.H.
Deposit date:2022-06-22
Release date:2022-10-12
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion.
Nat Commun, 13, 2022
8DFI
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BU of 8dfi by Molmil
Crystal structure of moderately neutralizing / interfering human monoclonal antibody 42C11 Fab in complex with MSP1-19
Descriptor: 42C11 Fab Heavy Chain, 42C11 Fab Light Chain, Merozoite surface protein 1
Authors:Patel, P.N, Tang, W.K, Tolia, N.H.
Deposit date:2022-06-22
Release date:2022-10-12
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion.
Nat Commun, 13, 2022

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