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PDB: 71 件
1IB6
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CRYSTAL STRUCTURE OF R153C E. COLI MALATE DEHYDROGENASE
分子名称: MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION
著者Bell, J.K, Yennawar, H.P, Wright, S.K, Thompson, J.R, Viola, R.E, Banaszak, L.J.
登録日2001-03-27
公開日2001-09-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Analyses of a Malate Dehydrogenase with a Variable Active Site
J.Biol.Chem., 276, 2001
4W8S
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Crystal structure of truncated hemolysin A Q125S/Y134S from P. mirabilis at 1.5 Angstroms resolution
分子名称: Hemolysin
著者Novak, W.R.P, Glasgow, E, Thompson, J.R, Weaver, T.M.
登録日2014-08-26
公開日2015-10-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.511 Å)
主引用文献Crystal structure of truncated hemolysin A Q125S/Y134S from P. mirabilis at 1.5 Angstroms resolution
To Be Published
4W8T
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Crystal structure of truncated hemolysin A Q125S from P. mirabilis at 1.5 Angstroms resolution
分子名称: Hemolysin
著者Novak, W.R.P, Glasgow, E, Thompson, J.R, Weaver, T.M.
登録日2014-08-26
公開日2015-10-07
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.539 Å)
主引用文献Crystal structure of truncated hemolysin A Q125S from P. mirabilis at 1.5 Angstroms resolution
To Be Published
8EEB
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BU of 8eeb by Molmil
Cryo-EM structure of human ABCA7 in Digitonin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Phospholipid-transporting ATPase ABCA7, ...
著者Alam, A, Le, L.T.M, Thompson, J.R.
登録日2022-09-06
公開日2022-12-21
最終更新日2023-02-15
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms.
Embo J., 42, 2023
8EE6
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Cryo-EM Structure of human ABCA7 in PE/Ch nanodiscs
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Phospholipid-transporting ATPase ABCA7, ...
著者Alam, A, Le, L.T.M, Thompson, J.R.
登録日2022-09-06
公開日2022-12-21
最終更新日2023-02-15
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms.
Embo J., 42, 2023
8EDW
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Cryo-EM Structure of human ABCA7 in BPL/Ch Nanodiscs
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Alam, A, Le, L.T.M, Thompson, J.R.
登録日2022-09-06
公開日2022-12-21
最終更新日2023-02-15
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms.
Embo J., 42, 2023
8EOP
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Cryo-EM Structure of Nanodisc reconstituted human ABCA7 EQ mutant in ATP bound closed state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Alam, A, Le, L.T.M, Thompson, J.R.
登録日2022-10-04
公開日2022-12-21
最終更新日2023-02-15
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms.
Embo J., 42, 2023
3SQF
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BU of 3sqf by Molmil
Crystal structure of monomeric M-PMV retroviral protease
分子名称: Protease
著者Jaskolski, M, Kazmierczyk, M, Gilski, M, Krzywda, S, Pichova, I, Zabranska, H, Khatib, F, DiMaio, F, Cooper, S, Thompson, J, Popovic, Z, Baker, D, Group, Foldit Contenders
登録日2011-07-05
公開日2011-09-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6324 Å)
主引用文献Crystal structure of a monomeric retroviral protease solved by protein folding game players.
Nat.Struct.Mol.Biol., 18, 2011
1IE3
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BU of 1ie3 by Molmil
CRYSTAL STRUCTURE OF R153C E. COLI MALATE DEHYDROGENASE
分子名称: MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYRUVIC ACID
著者Bell, J.K, Yennawar, H.P, Wright, S.K, Thompson, J.R, Viola, R.E, Banaszak, L.J.
登録日2001-04-05
公開日2001-09-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Analyses of a Malate Dehydrogenase with a Variable Active Site
J.Biol.Chem., 276, 2001
3SZM
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STRUCTURE OF HUMAN MICROCEPHALIN (MCPH1) TANDEM BRCT DOMAINS IN COMPLEX WITH A GAMMA-H2AX PHOSPHOPEPTIDE
分子名称: Histone H2A.x, Microcephalin
著者Singh, N, Thompson, J.R, Mer, G.
登録日2011-07-19
公開日2011-11-30
最終更新日2012-09-19
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Dual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1.
Proc.Natl.Acad.Sci.USA, 109, 2012
3T1N
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Structure of human MICROCEPHALIN (MCPH1) TANDEM BRCT domains in complex with a CDC27 phosphopeptide
分子名称: Cdc27 peptide, Microcephalin
著者Singh, N, Thompson, J.R, Mer, G.
登録日2011-07-22
公開日2011-11-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular Basis for the Association of Microcephalin (MCPH1) Protein with the Cell Division Cycle Protein 27 (Cdc27) Subunit of the Anaphase-promoting Complex.
J.Biol.Chem., 287, 2012
3U3Z
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BU of 3u3z by Molmil
Structure of human microcephalin (MCPH1) tandem BRCT domains in complex with an H2A.X peptide phosphorylated at Ser139 and Tyr142
分子名称: GLYCEROL, Histone H2A.X peptide, Microcephalin
著者Singh, N, Thompson, J.R, Heroux, A, Mer, G.
登録日2011-10-06
公開日2012-07-25
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Dual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1.
Proc.Natl.Acad.Sci.USA, 109, 2012
3P8D
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BU of 3p8d by Molmil
Crystal structure of the second Tudor domain of human PHF20 (homodimer form)
分子名称: Medulloblastoma antigen MU-MB-50.72
著者Cui, G, Lee, J, Thompson, J.R, Botuyan, M.V, Mer, G.
登録日2010-10-13
公開日2011-06-22
最終更新日2012-09-26
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53.
Nat.Struct.Mol.Biol., 19, 2012
3FY3
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Crystal structure of truncated hemolysin A from P. mirabilis
分子名称: Hemolysin
著者Weaver, T.M, Thompson, J.R, Bailey, L.J, Wawrzyn, G.T, Hocking, J.M, Howard, D.R.
登録日2009-01-21
公開日2009-06-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and functional studies of truncated hemolysin A from Proteus mirabilis.
J.Biol.Chem., 284, 2009
3SD4
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BU of 3sd4 by Molmil
Crystal structure of the first Tudor domain of human PHF20
分子名称: PHD finger protein 20
著者Cui, G, Botuyan, M.V, Thompson, J.R, Mer, G.
登録日2011-06-08
公開日2011-06-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.928 Å)
主引用文献PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53.
Nat.Struct.Mol.Biol., 19, 2012
3U79
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BU of 3u79 by Molmil
AL-103 Y32F Y96F
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, Amyloidogenic immunoglobulin light chain protein AL-103 Y32F Y96F, ...
著者DiCostanzo, A.C, Thompson, J.R, Ramirez-Alvarado, M.
登録日2011-10-13
公開日2012-07-04
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Tyrosine Residues mediate crucial interactions in amyloid formation for immunoglobulin light chains
To be Published
3DVF
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BU of 3dvf by Molmil
Structure of amyloidogenic kappa 1 Bence Jones protein
分子名称: Amyloidogenic immunoglobulin light chain protein AL-12
著者Randles, E.G, Thompson, J.R, Ramirez-Alvarado, M.
登録日2008-07-18
公開日2009-05-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural alterations within native amyloidogenic immunoglobulin light chains.
J.Mol.Biol., 389, 2009
6CO2
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BU of 6co2 by Molmil
Structure of an engineered protein (NUDT16TI) in complex with 53BP1 Tudor domains
分子名称: NUDT16-Tudor-interacting (NUDT16TI), TP53-binding protein 1
著者Botuyan, M.V, Thompson, J.R, Cui, G, Mer, G.
登録日2018-03-10
公開日2018-06-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein.
Nat. Struct. Mol. Biol., 25, 2018
3CDF
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BU of 3cdf by Molmil
kI O18/O8 Y87H immunoglobulin light chain variable domain
分子名称: IMMUNOGLOBULIN LIGHT CHAIN
著者Baden, E.M, Randles, E.G, Thompson, J.R, Ramirez-Alvarado, M.
登録日2008-02-26
公開日2008-09-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Structural insights into the role of mutations in amyloidogenesis.
J.Biol.Chem., 283, 2008
3PD7
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BU of 3pd7 by Molmil
Crystal Structure of the Sixth BRCT Domain of Human TopBP1
分子名称: DNA topoisomerase 2-binding protein 1
著者Lee, J, Xu, C, Cui, G, Thompson, J.R, Mer, G.
登録日2010-10-22
公開日2010-12-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Crystal Structure of the Sixth BRCT Domain of Human TopBP1
To be Published
3Q68
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Structure of the Vps75-Rtt109 histone chaperone-lysine acetyltransferase complex (Full-length proteins in space group P212121)
分子名称: Histone acetyltransferase RTT109, Vacuolar protein sorting-associated protein 75 (VPS75)
著者Su, D, Thompson, J.R, Mer, G.
登録日2010-12-30
公開日2011-03-23
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.705 Å)
主引用文献Structure and histone binding properties of the Vps75-Rtt109 chaperone-lysine acetyltransferase complex.
J.Biol.Chem., 286, 2011
3Q66
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Structure of the Vps75-Rtt109 histone chaperone-lysine acetyltransferase complex (Full-length proteins in space group P6122)
分子名称: Histone acetyltransferase RTT109, SULFATE ION, Vacuolar protein sorting-associated protein 75
著者Su, D, Thompson, J.R, Mer, G.
登録日2010-12-30
公開日2011-03-23
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.705 Å)
主引用文献Structure and histone binding properties of the Vps75-Rtt109 chaperone-lysine acetyltransferase complex.
J.Biol.Chem., 286, 2011
1SNK
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Cathepsin K complexed with carbamate derivatized norleucine aldehyde
分子名称: Cathepsin K, N2-({[(4-BROMOPHENYL)METHYL]OXY}CARBONYL)-N1-[(1S)-1-FORMYLPENTYL]-L-LEUCINAMIDE, SULFATE ION
著者Boros, E.E, Deaton, D.N, Hassell, A.M, McFadyen, R.B, Miller, A.B, Miller, L.R, Shewchuk, L.M, Thompson, J.B, Willard Jr, D.H, Wright, L.L.
登録日2004-03-11
公開日2004-06-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Exploration of the P(2)-P(3) SAR of aldehyde cathepsin K inhibitors
Bioorg.Med.Chem.Lett., 14, 2004
3CDC
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kI O18/O8 N34I/Y87H immunoglobulin light chain variable domain
分子名称: Light Chain Amyloidogenic
著者Baden, E.M, Randles, E.G, Thompson, J.R, Ramirez-Alvarado, M.
登録日2008-02-26
公開日2008-09-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Structural insights into the role of mutations in amyloidogenesis.
J.Biol.Chem., 283, 2008
3CDY
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AL-09 H87Y, immunoglobulin light chain variable domain
分子名称: IMMUNOGLOBULIN LIGHT CHAIN
著者Baden, E.M, Randles, E.G, Aboagye, A.K, Thompson, J.R, Ramirez-Alvarado, M.
登録日2008-02-27
公開日2008-09-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Structural insights into the role of mutations in amyloidogenesis.
J.Biol.Chem., 283, 2008

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件を2024-05-29に公開中

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