4A1I
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![BU of 4a1i by Molmil](/molmil-images/mine/4a1i) | ykud from B.subtilis | Descriptor: | CADMIUM ION, CHLORIDE ION, PUTATIVE L, ... | Authors: | Blaise, M, Fuglsang Midtgaard, S, Roi Midtgaard, S, Boesen, T, Thirup, S. | Deposit date: | 2011-09-15 | Release date: | 2012-09-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Structures of Three New Crystal Forms of the Ykud L,D-Transpeptidase from B. Subtilis. To be Published
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4ACJ
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![BU of 4acj by Molmil](/molmil-images/mine/4acj) | Crystal structure of the TLDC domain of Oxidation resistance protein 2 from zebrafish | Descriptor: | WU:FB25H12 PROTEIN, | Authors: | Blaise, M, B Alsarraf, H.M.A, Wong, J.E.M.M, Midtgaard, S.R, Laroche, F, Schack, L, Spaink, H, Stougaard, J, Thirup, S. | Deposit date: | 2011-12-15 | Release date: | 2012-02-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (0.97 Å) | Cite: | Crystal Structure of the Tldc Domain of Oxidation Resistance Protein 2 from Zebrafish. Proteins, 80, 2012
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3G2W
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![BU of 3g2w by Molmil](/molmil-images/mine/3g2w) | VHS Domain of human GGA1 complexed with a DXXLL hinge peptide | Descriptor: | ADP-ribosylation factor-binding protein GGA1, Internal peptide of the Hinge domain of ADP-ribosylation factor-binding protein GGA1 | Authors: | Cramer, J.F, Behrens, M.A, Gustafsen, C, Oliveira, C.L.P, Pedersen, J.S, Madsen, P, Petersen, C.M, Thirup, S.S. | Deposit date: | 2009-02-01 | Release date: | 2009-12-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | GGA autoinhibition revisited Traffic, 11, 2010
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3G2V
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![BU of 3g2v by Molmil](/molmil-images/mine/3g2v) | VHS Domain of human GGA1 complexed with Sotilin C-terminal Phosphopeptide | Descriptor: | ADP-ribosylation factor-binding protein GGA1, C-terminal fragment of Sortilin, IODIDE ION | Authors: | Cramer, J.F, Behrens, M.A, Gustafsen, C, Oliveira, C.L.P, Pedersen, J.S, Madsen, P, Petersen, C.M, Thirup, S.S. | Deposit date: | 2009-02-01 | Release date: | 2009-12-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | GGA autoinhibition revisited Traffic, 11, 2010
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3G2U
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![BU of 3g2u by Molmil](/molmil-images/mine/3g2u) | VHS Domain of human GGA1 complexed with Sotilin C-terminal Peptide | Descriptor: | ADP-ribosylation factor-binding protein GGA1, C-terminal fragment of Sortilin, IODIDE ION | Authors: | Cramer, J.F, Behrens, M.A, Gustafsen, C, Oliveira, C.L.P, Pedersen, J.S, Madsen, P, Petersen, C.M, Thirup, S.S. | Deposit date: | 2009-02-01 | Release date: | 2009-12-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | GGA autoinhibition revisited Traffic, 11, 2010
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3G2S
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![BU of 3g2s by Molmil](/molmil-images/mine/3g2s) | VHS Domain of human GGA1 complexed with SorLA C-terminal Peptide | Descriptor: | ADP-ribosylation factor-binding protein GGA1, C-terminal fragment of Sortilin-related receptor, HEXANE-1,6-DIOL | Authors: | Cramer, J.F, Behrens, M.A, Gustafsen, C, Oliveira, C.L.P, Pedersen, J.S, Madsen, P, Petersen, C.M, Thirup, S.S. | Deposit date: | 2009-02-01 | Release date: | 2009-12-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | GGA autoinhibition revisited Traffic, 11, 2010
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3G2T
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![BU of 3g2t by Molmil](/molmil-images/mine/3g2t) | VHS Domain of human GGA1 complexed with SorLA C-terminal Phosphopeptide | Descriptor: | ADP-ribosylation factor-binding protein GGA1, IODIDE ION, Phosphorylated C-terminal fragment of Sortilin-related receptor | Authors: | Cramer, J.F, Behrens, M.A, Gustafsen, C, Oliveira, C.L.P, Pedersen, J.S, Madsen, P, Petersen, C.M, Thirup, S.S. | Deposit date: | 2009-02-01 | Release date: | 2009-12-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | GGA autoinhibition revisited Traffic, 11, 2010
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3F6K
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![BU of 3f6k by Molmil](/molmil-images/mine/3f6k) | Crystal structure of the Vps10p domain of human sortilin/NTS3 in complex with neurotensin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Neurotensin, ... | Authors: | Quistgaard, E.M, Madsen, P, Groftehauge, M.K, Nissen, P, Petersen, C.M, Thirup, S. | Deposit date: | 2008-11-06 | Release date: | 2008-12-30 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Ligands bind to Sortilin in the tunnel of a ten-bladed beta-propeller domain. Nat.Struct.Mol.Biol., 16, 2009
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4PO7
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![BU of 4po7 by Molmil](/molmil-images/mine/4po7) | Structure of the Sortilin:neurotensin complex at excess neurotensin concentration | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Neurotensin/neuromedin N, Sortilin, ... | Authors: | Quistgaard, E.M, Groftehauge, M.K, Thirup, S.S. | Deposit date: | 2014-02-25 | Release date: | 2014-07-23 | Last modified: | 2020-10-21 | Method: | X-RAY DIFFRACTION (2.66 Å) | Cite: | Revisiting the structure of the Vps10 domain of human sortilin and its interaction with neurotensin. Protein Sci., 23, 2014
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1D2E
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![BU of 1d2e by Molmil](/molmil-images/mine/1d2e) | CRYSTAL STRUCTURE OF MITOCHONDRIAL EF-TU IN COMPLEX WITH GDP | Descriptor: | ELONGATION FACTOR TU (EF-TU), GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | Authors: | Andersen, G.R, Thirup, S, Spremulli, L.L, Nyborg, J. | Deposit date: | 1999-09-23 | Release date: | 1999-09-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | High resolution crystal structure of bovine mitochondrial EF-Tu in complex with GDP. J.Mol.Biol., 297, 2000
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1B23
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![BU of 1b23 by Molmil](/molmil-images/mine/1b23) | E. coli cysteinyl-tRNA and T. aquaticus elongation factor EF-TU:GTP ternary complex | Descriptor: | CYSTEINE, CYSTEINYL TRNA, ELONGATION FACTOR TU, ... | Authors: | Nissen, P, Kjeldgaard, M, Thirup, S, Nyborg, J. | Deposit date: | 1998-12-04 | Release date: | 1998-12-07 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The crystal structure of Cys-tRNACys-EF-Tu-GDPNP reveals general and specific features in the ternary complex and in tRNA. Structure Fold.Des., 7, 1999
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1AYO
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![BU of 1ayo by Molmil](/molmil-images/mine/1ayo) | RECEPTOR BINDING DOMAIN OF BOVINE ALPHA-2-MACROGLOBULIN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-2-MACROGLOBULIN, CALCIUM ION | Authors: | Jenner, L.B, Husted, L, Thirup, S, Sottrup-Jensen, L, Nyborg, J. | Deposit date: | 1997-11-07 | Release date: | 1998-11-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the receptor-binding domain of alpha 2-macroglobulin. Structure, 6, 1998
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1EFT
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![BU of 1eft by Molmil](/molmil-images/mine/1eft) | THE CRYSTAL STRUCTURE OF ELONGATION FACTOR EF-TU FROM THERMUS AQUATICUS IN THE GTP CONFORMATION | Descriptor: | ELONGATION FACTOR TU, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | Authors: | Kjeldgaard, M, Nissen, P, Thirup, S, Nyborg, J. | Deposit date: | 1993-08-24 | Release date: | 1994-08-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure of elongation factor EF-Tu from Thermus aquaticus in the GTP conformation. Structure, 1, 1993
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4MSL
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![BU of 4msl by Molmil](/molmil-images/mine/4msl) | Crystal structure of the Vps10p domain of human sortilin/NTS3 in complex with AF40431 | Descriptor: | N-[(7-hydroxy-4-methyl-2-oxo-2H-chromen-8-yl)methyl]-L-leucine, Sortilin, TETRAETHYLENE GLYCOL, ... | Authors: | Andersen, J.L, Strandbygaard, D, Thirup, S. | Deposit date: | 2013-09-18 | Release date: | 2014-02-12 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Identification of the first small-molecule ligand of the neuronal receptor sortilin and structure determination of the receptor-ligand complex. Acta Crystallogr.,Sect.D, 70, 2014
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4N7E
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![BU of 4n7e by Molmil](/molmil-images/mine/4n7e) | Crystal structure of the Vps10p domain of human sortilin/NTS3 in complex with AF38469 | Descriptor: | 2-[(6-methylpyridin-2-yl)carbamoyl]-5-(trifluoromethyl)benzoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Sortilin, ... | Authors: | Andersen, J.L, Strandbygaard, D, Thirup, S. | Deposit date: | 2013-10-15 | Release date: | 2014-01-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The identification of AF38469: An orally bioavailable inhibitor of the VPS10P family sorting receptor Sortilin. Bioorg.Med.Chem.Lett., 24, 2014
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