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PDB: 39 results
7RR0
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BU of 7rr0 by Molmil
SARS-CoV-2 receptor binding domain bound to Fab PDI 222
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PDI 222 Fab Heavy Chain, PDI 222 Fab Light Chain, ...
Authors:Pymm, P, Glukhova, A, Black, K.A, Tham, W.H.
Deposit date:2021-08-08
Release date:2021-10-06
Last modified:2021-10-27
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain.
Cell Rep, 37, 2021
8TZU
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BU of 8tzu by Molmil
OC43 S1b domain in complex with WNb 293 and WNb 317
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Pymm, P, Feng, J, Tham, W.H.
Deposit date:2023-08-27
Release date:2024-05-01
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:OC43 S1b domain in complex with WNb 293 and WNb 317
To Be Published
4Z8N
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BU of 4z8n by Molmil
Crystal structure of the erythrocyte-binding domain from Plasmodium vivax reticulocyte-binding protein 2a (PvRBP2a)
Descriptor: CALCIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Gruszczyk, J, Tham, W.H.
Deposit date:2015-04-09
Release date:2015-12-16
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.124 Å)
Cite:Structurally conserved erythrocyte-binding domain in Plasmodium provides a versatile scaffold for alternate receptor engagement.
Proc.Natl.Acad.Sci.USA, 113, 2016
5W53
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BU of 5w53 by Molmil
Crystal structure of the erythrocyte-binding domain from Plasmodium vivax reticulocyte-binding protein 2b (PvRBP2b)
Descriptor: POTASSIUM ION, Reticulocyte binding protein 2, putative, ...
Authors:Gruszczyk, J, Tham, W.H.
Deposit date:2017-06-13
Release date:2017-11-29
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Transferrin receptor 1 is a reticulocyte-specific receptor for Plasmodium vivax.
Science, 359, 2018
6WNO
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BU of 6wno by Molmil
Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 243244
Descriptor: 243244 Fab heavy chain, 243244 Fab light chain, Plasmodium vivax reticulocyte binding protein 2b
Authors:Chan, L.J, Dietrich, M.H, Tham, W.H.
Deposit date:2020-04-23
Release date:2021-01-27
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b.
Nat Commun, 12, 2021
6WTV
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BU of 6wtv by Molmil
Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 258259
Descriptor: 258259 Fab heavy chain, 258259 Fab light chain, reticulocyte binding protein 2b
Authors:Chan, L.J, Dietrich, M.H, Tham, W.H.
Deposit date:2020-05-04
Release date:2021-01-27
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b.
Nat Commun, 12, 2021
6WOZ
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BU of 6woz by Molmil
Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 251249
Descriptor: 251249 Fab heavy chain, 251249 Fab light chain, reticulocyte binding protein 2b
Authors:Chan, L.J, Dietrich, M.H, Tham, W.H.
Deposit date:2020-04-26
Release date:2021-01-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b.
Nat Commun, 12, 2021
6WTY
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BU of 6wty by Molmil
Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 253245
Descriptor: 253245 Fab heavy chain, 253245 Fab light chain, reticulocyte binding protein 2b
Authors:Chan, L.J, Dietrich, M.H, Tham, W.H.
Deposit date:2020-05-04
Release date:2021-01-27
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.481 Å)
Cite:Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b.
Nat Commun, 12, 2021
7USS
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BU of 7uss by Molmil
Plasmodium falciparum protein Pfs230 Pro-D1D2 - Structure of the first two 6-cysteine domains with N-terminal extension
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Gametocyte surface protein P230, ...
Authors:Dietrich, M.H, Tham, W.H.
Deposit date:2022-04-25
Release date:2022-12-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Nanobodies against Pfs230 block Plasmodium falciparum transmission.
Biochem.J., 479, 2022
7UST
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BU of 7ust by Molmil
Plasmodium falciparum protein Pfs230 D1 in complex with nanobody F5
Descriptor: Gametocyte surface protein P230, Nanobody F5, SULFATE ION
Authors:Dietrich, M.H, Tham, W.H.
Deposit date:2022-04-25
Release date:2022-12-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Nanobodies against Pfs230 block Plasmodium falciparum transmission.
Biochem.J., 479, 2022
7USR
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BU of 7usr by Molmil
Plasmodium falciparum protein Pfs230 D1D2 - Structure of the first two 6-cysteine domains
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Gametocyte surface protein P230
Authors:Dietrich, M.H, Tham, W.H.
Deposit date:2022-04-25
Release date:2022-12-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Nanobodies against Pfs230 block Plasmodium falciparum transmission.
Biochem.J., 479, 2022
7USV
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BU of 7usv by Molmil
Plasmodium falciparum protein Pfs230 D1 in complex with nanobody F10
Descriptor: Gametocyte surface protein P230, Nanobody F10, SULFATE ION
Authors:Dietrich, M.H, Tham, W.H.
Deposit date:2022-04-25
Release date:2022-12-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Nanobodies against Pfs230 block Plasmodium falciparum transmission.
Biochem.J., 479, 2022
6WM9
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BU of 6wm9 by Molmil
Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 237235
Descriptor: 237235 Fab heavy chain, 237235 Fab light chain, Reticulocyte binding protein 2b
Authors:Chan, L.J, Dietrich, M.H, Tham, W.H.
Deposit date:2020-04-20
Release date:2021-01-27
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b.
Nat Commun, 12, 2021
6WTU
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BU of 6wtu by Molmil
Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 273264
Descriptor: 273264 Fab heavy chain, 273264 Fab light chain, reticulocyte binding protein 2b
Authors:Chan, L.J, Dietrich, M.H, Tham, W.H.
Deposit date:2020-05-04
Release date:2021-01-27
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b.
Nat Commun, 12, 2021
6WN1
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BU of 6wn1 by Molmil
Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 241242
Descriptor: 241242 Fab heavy chain, 241242 Fab light chain, Reticulocyte binding protein 2b
Authors:Chan, L.J, Dietrich, M.H, Tham, W.H.
Deposit date:2020-04-22
Release date:2021-01-27
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b.
Nat Commun, 12, 2021
6WQO
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BU of 6wqo by Molmil
Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 283284
Descriptor: 283284 Fab heavy chain, 283284 Fab light chain, reticulocyte binding protein 2b
Authors:Chan, L.J, Dietrich, M.H, Tham, W.H.
Deposit date:2020-04-29
Release date:2021-01-27
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b.
Nat Commun, 12, 2021
7KJI
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BU of 7kji by Molmil
Plasmodium falciparum protein Pf12p bound to nanobody D9
Descriptor: Nanobody D9, Surface protein P12p
Authors:Dietrich, M.H, Tham, W.H.
Deposit date:2020-10-26
Release date:2021-02-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Nanobody generation and structural characterization of Plasmodium falciparum 6-cysteine protein Pf12p.
Biochem.J., 478, 2021
7KJH
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BU of 7kjh by Molmil
Plasmodium falciparum protein Pf12p bound to nanobody B9
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRATE ANION, Nanobody B9, ...
Authors:Dietrich, M.H, Tham, W.H.
Deposit date:2020-10-26
Release date:2021-02-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Nanobody generation and structural characterization of Plasmodium falciparum 6-cysteine protein Pf12p.
Biochem.J., 478, 2021
7S7R
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BU of 7s7r by Molmil
Plasmodium falciparum protein Pf12 bound to nanobody G7
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Merozoite surface protein P12, Nanobody G7, ...
Authors:Dietrich, M.H, Tham, W.H.
Deposit date:2021-09-17
Release date:2022-03-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structure of the Pf12 and Pf41 heterodimeric complex of Plasmodium falciparum 6-cysteine proteins.
FEMS Microbes, 3, 2022
7KJ7
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BU of 7kj7 by Molmil
Plasmodium falciparum protein Pf12p
Descriptor: Surface protein P12p
Authors:Dietrich, M.H, Tham, W.H.
Deposit date:2020-10-26
Release date:2021-02-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Nanobody generation and structural characterization of Plasmodium falciparum 6-cysteine protein Pf12p.
Biochem.J., 478, 2021
7LDJ
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BU of 7ldj by Molmil
SARS-CoV-2 receptor binding domain in complex with WNb-2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody 2, ...
Authors:Pymm, P, Dietrich, M.H, Tan, L.L, Adair, A, Tham, W.H.
Deposit date:2021-01-13
Release date:2021-05-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:SARS-CoV-2 receptor binding domain in complex with WNb-2
Proc.Natl.Acad.Sci.USA, 2021
6BPD
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BU of 6bpd by Molmil
Plasmodium vivax invasion blocking monoclonal antibody 10B12
Descriptor: Monoclonal antibody 10B12 Fab heavy chain, Monoclonal antibody 10B12 Fab light chain
Authors:Gruszczyk, J, Chan, L.J, Tham, W.H.
Deposit date:2017-11-22
Release date:2018-06-20
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
7S7Q
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BU of 7s7q by Molmil
Heterodimeric complex of Pf12 and Pf41 of Plasmodium falciparum
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, Merozoite surface protein P12, ...
Authors:Dietrich, M.H, Tham, W.H.
Deposit date:2021-09-17
Release date:2022-03-02
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure of the Pf12 and Pf41 heterodimeric complex of Plasmodium falciparum 6-cysteine proteins.
FEMS Microbes, 3, 2022
6D03
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BU of 6d03 by Molmil
Cryo-EM structure of a Plasmodium vivax invasion complex essential for entry into human reticulocytes; one molecule of parasite ligand.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(2-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gruszczyk, J, Huang, R.K, Hong, C, Yu, Z, Tham, W.H.
Deposit date:2018-04-10
Release date:2018-06-20
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6D05
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BU of 6d05 by Molmil
Cryo-EM structure of a Plasmodium vivax invasion complex essential for entry into human reticulocytes; two molecules of parasite ligand, subclass 2.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Gruszczyk, J, Huang, R.K, Hong, C, Yu, Z, Tham, W.H.
Deposit date:2018-04-10
Release date:2018-06-20
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018

 

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