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PDB: 8 件
3UZT
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BU of 3uzt by Molmil
Structure of the C13.18 RNA Aptamer in Complex with G Protein-Coupled Receptor Kinase 2
分子名称: Beta-adrenergic receptor kinase 1, C13.18 RNA Aptamer, MAGNESIUM ION
著者Tesmer, J.J.G, Tesmer, V.M.
登録日2011-12-07
公開日2012-07-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.51 Å)
主引用文献Molecular mechanism for inhibition of g protein-coupled receptor kinase 2 by a selective RNA aptamer.
Structure, 20, 2012
3UZS
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BU of 3uzs by Molmil
Structure of the C13.28 RNA Aptamer Bound to the G Protein-Coupled Receptor Kinase 2-Heterotrimeric G Protein Beta 1 and Gamma 2 Subunit Complex
分子名称: Beta-adrenergic receptor kinase 1, C13.28 RNA Aptamer, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Tesmer, J.J.G, Tesmer, V.M.
登録日2011-12-07
公開日2012-07-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (4.52 Å)
主引用文献Molecular mechanism for inhibition of g protein-coupled receptor kinase 2 by a selective RNA aptamer.
Structure, 20, 2012
2ACX
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BU of 2acx by Molmil
Crystal Structure of G protein coupled receptor kinase 6 bound to AMPPNP
分子名称: G protein-coupled receptor kinase 6, MAGNESIUM ION, PHOSPHATE ION, ...
著者Lodowski, D.T, Tesmer, V.M, Benovic, J.L, Tesmer, J.J.
登録日2005-07-19
公開日2006-04-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Structure of G Protein-coupled Receptor Kinase (GRK)-6 Defines a Second Lineage of GRKs.
J.Biol.Chem., 281, 2006
3KRW
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BU of 3krw by Molmil
Human GRK2 in complex with Gbetgamma subunits and balanol (soak)
分子名称: BALANOL, Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Tesmer, J.J.G, Tesmer, V.M.
登録日2009-11-19
公開日2010-02-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of human g protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol.
J.Med.Chem., 53, 2010
3KRX
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BU of 3krx by Molmil
Human GRK2 in complex with Gbetgamma subunits and balanol (co-crystal)
分子名称: BALANOL, Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Tesmer, J.J.G, Tesmer, V.M.
登録日2009-11-19
公開日2010-02-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of human g protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol.
J.Med.Chem., 53, 2010
8SH1
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BU of 8sh1 by Molmil
Structure of human POT1 DNA binding domain bound to a 5'-phosphorylated junction of a telomeric double-stranded DNA duplex with a 3'-overhang
分子名称: DNA (5'-D(*CP*GP*CP*GP*CP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3'), DNA (5'-D(P*CP*TP*AP*AP*CP*GP*CP*GP*CP*G)-3'), Protection of telomeres protein 1
著者Nandakumar, J, Tesmer, V.M.
登録日2023-04-13
公開日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Human POT1 protects the telomeric ds-ss DNA junction by capping the 5' end of the chromosome.
Science, 381, 2023
8SH0
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BU of 8sh0 by Molmil
Structure of human POT1 DNA binding domain bound to a 5'-phosphorylated junction of a telomeric DNA hairpin with a 3'-overhang
分子名称: ACETATE ION, DNA (5'-D(P*CP*CP*AP*GP*CP*AP*GP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3'), Protection of telomeres protein 1
著者Nandakumar, J, Tesmer, V.M.
登録日2023-04-13
公開日2023-08-30
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Human POT1 protects the telomeric ds-ss DNA junction by capping the 5' end of the chromosome.
Science, 381, 2023
5WIR
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BU of 5wir by Molmil
Structure of the TRF1-TERB1 interface
分子名称: TERB1-TBM, Telomeric repeat-binding factor 1
著者Nandakumar, J, Pendlebury, D.F, Smith, E.M, Tesmer, V.M.
登録日2017-07-20
公開日2017-10-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Dissecting the telomere-inner nuclear membrane interface formed in meiosis.
Nat. Struct. Mol. Biol., 24, 2017

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件を2024-07-10に公開中

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