1G4I
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![BU of 1g4i by Molmil](/molmil-images/mine/1g4i) | Crystal structure of the bovine pancreatic phospholipase A2 at 0.97A | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, ... | Authors: | Steiner, R.A, Rozeboom, H.J, de Vries, A, Kalk, K.H, Murshudov, G.N, Wilson, K.S, Dijkstra, B.W. | Deposit date: | 2000-10-27 | Release date: | 2001-04-04 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (0.97 Å) | Cite: | X-ray structure of bovine pancreatic phospholipase A2 at atomic resolution. Acta Crystallogr.,Sect.D, 57, 2001
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3V16
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![BU of 3v16 by Molmil](/molmil-images/mine/3v16) | An intramolecular pi-cation latch in phosphatidylinositol-specific phospholipase C from S.aureus controls substrate access to the active site | Descriptor: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, 1-phosphatidylinositol phosphodiesterase, CHLORIDE ION | Authors: | Goldstein, R.I, Cheng, J, Stec, B, Roberts, M.F. | Deposit date: | 2011-12-09 | Release date: | 2012-04-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure of the S. aureus PI-Specific Phospholipase C Reveals Modulation of Active Site Access by a Titratable PI-Cation Latched Loop Biochemistry, 51, 2012
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3V18
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![BU of 3v18 by Molmil](/molmil-images/mine/3v18) | Structure of the Phosphatidylinositol-specific phospholipase C from Staphylococcus aureus | Descriptor: | 1-phosphatidylinositol phosphodiesterase, ISOPROPYL ALCOHOL, SULFATE ION | Authors: | Goldstein, R.I, Cheng, J, Stec, B, Roberts, M.F. | Deposit date: | 2011-12-09 | Release date: | 2012-04-04 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Structure of the S. aureus PI-Specific Phospholipase C Reveals Modulation of Active Site Access by a Titratable PI-Cation Latched Loop Biochemistry, 51, 2012
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7Z0T
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![BU of 7z0t by Molmil](/molmil-images/mine/7z0t) | Structure of the Escherichia coli formate hydrogenlyase complex (aerobic preparation, composite structure) | Descriptor: | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, CARBONMONOXIDE-(DICYANO) IRON, FE (III) ION, ... | Authors: | Steinhilper, R, Murphy, B.J. | Deposit date: | 2022-02-23 | Release date: | 2022-09-28 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure of the membrane-bound formate hydrogenlyase complex from Escherichia coli. Nat Commun, 13, 2022
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7Z0S
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![BU of 7z0s by Molmil](/molmil-images/mine/7z0s) | |
3V1H
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![BU of 3v1h by Molmil](/molmil-images/mine/3v1h) | Structure of the H258Y mutant of Phosphatidylinositol-specific phospholipase C from Staphylococcus aureus | Descriptor: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, 1-phosphatidylinositol phosphodiesterase, ACETATE ION | Authors: | Goldstein, R.I, Cheng, J, Stec, B, Roberts, M.F. | Deposit date: | 2011-12-09 | Release date: | 2012-04-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the S. aureus PI-Specific Phospholipase C Reveals Modulation of Active Site Access by a Titratable PI-Cation Latched Loop Biochemistry, 51, 2012
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2OD7
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![BU of 2od7 by Molmil](/molmil-images/mine/2od7) | Crystal Structure of yHst2 bound to the intermediate analogue ADP-HPD, and and aceylated H4 peptide | Descriptor: | 5'-O-[(S)-{[(S)-{[(2R,3R,4S)-3,4-DIHYDROXYPYRROLIDIN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE, Acetylated histone H4 peptide, NAD-dependent deacetylase HST2, ... | Authors: | Marmorstein, R.Q, Sanders, B.D. | Deposit date: | 2006-12-21 | Release date: | 2007-02-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for nicotinamide inhibition and base exchange in sir2 enzymes. Mol.Cell, 25, 2007
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3RBG
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![BU of 3rbg by Molmil](/molmil-images/mine/3rbg) | Crystal structure analysis of Class-I MHC restricted T-cell associated molecule | Descriptor: | Cytotoxic and regulatory T-cell molecule, PHOSPHATE ION | Authors: | Rubinstein, R, Ramagopal, U.A, Toro, R, Nathenson, S.G, Fiser, A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN) | Deposit date: | 2011-03-29 | Release date: | 2011-05-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Functional classification of immune regulatory proteins. Structure, 21, 2013
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2OD9
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![BU of 2od9 by Molmil](/molmil-images/mine/2od9) | Structural Basis for Nicotinamide Inhibition and Base Exchange in Sir2 Enzymes | Descriptor: | 5'-O-[(S)-{[(S)-{[(2R,3R,4S)-3,4-DIHYDROXYPYRROLIDIN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE, H4 peptide, NAD-dependent deacetylase HST2, ... | Authors: | Marmorstein, R, Sanders, B.D. | Deposit date: | 2006-12-21 | Release date: | 2007-02-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis for nicotinamide inhibition and base exchange in sir2 enzymes. Mol.Cell, 25, 2007
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2QQF
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![BU of 2qqf by Molmil](/molmil-images/mine/2qqf) | Hst2 bound to ADP-HPD and Acetylated histone H4 | Descriptor: | 5'-O-[(S)-{[(S)-{[(2R,3R,4S)-3,4-DIHYDROXYPYRROLIDIN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE, Histone H4, NAD-dependent deacetylase HST2, ... | Authors: | Marmorstein, R, Sanders, B.D, Zhao, K, Slama, J. | Deposit date: | 2007-07-26 | Release date: | 2007-10-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for nicotinamide inhibition and base exchange in sir2 enzymes. Mol.Cell, 25, 2007
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2QQG
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![BU of 2qqg by Molmil](/molmil-images/mine/2qqg) | Hst2 bound to ADP-HPD, acetyllated histone H4 and nicotinamide | Descriptor: | 5'-O-[(S)-{[(S)-{[(2R,3R,4S)-3,4-DIHYDROXYPYRROLIDIN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE, Histone H4, NAD-dependent deacetylase HST2, ... | Authors: | Marmorstein, R, Sanders, B, Zhao, K, Slama, J. | Deposit date: | 2007-07-26 | Release date: | 2007-10-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis for nicotinamide inhibition and base exchange in sir2 enzymes. Mol.Cell, 25, 2007
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1D66
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![BU of 1d66 by Molmil](/molmil-images/mine/1d66) | DNA RECOGNITION BY GAL4: STRUCTURE OF A PROTEIN/DNA COMPLEX | Descriptor: | CADMIUM ION, DNA (5'-D(*CP*CP*GP*GP*AP*GP*GP*AP*CP*AP*GP*TP*CP*CP*TP*CP*C P*GP*G)-3'), DNA (5'-D(*CP*CP*GP*GP*AP*GP*GP*AP*CP*TP*GP*TP*CP*CP*TP*CP*C P*GP*G)-3'), ... | Authors: | Marmorstein, R, Carey, M, Ptashne, M, Harrison, S.C. | Deposit date: | 1992-03-06 | Release date: | 1992-03-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | DNA recognition by GAL4: structure of a protein-DNA complex. Nature, 356, 1992
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2I32
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![BU of 2i32 by Molmil](/molmil-images/mine/2i32) | |
1PYI
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![BU of 1pyi by Molmil](/molmil-images/mine/1pyi) | |
1W19
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![BU of 1w19 by Molmil](/molmil-images/mine/1w19) | Lumazine Synthase from Mycobacterium tuberculosis bound to 3-(1,3,7- trihydro-9-D-ribityl-2,6,8-purinetrione-7-yl)propane 1-phosphate | Descriptor: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, (4S,5S)-1,2-DITHIANE-4,5-DIOL, ... | Authors: | Morgunova, E, Meining, W, Illarionov, B, Haase, I, Fischer, M, Cushman, M, Bacher, A, Ladenstein, R. | Deposit date: | 2004-06-03 | Release date: | 2005-03-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Lumazine Synthase from Mycobacterium Tuberculosis as a Target for Rational Drug Design: Binding Mode of a New Class of Purinetrione Inhibitors(,) Biochemistry, 44, 2005
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1EJB
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![BU of 1ejb by Molmil](/molmil-images/mine/1ejb) | LUMAZINE SYNTHASE FROM SACCHAROMYCES CEREVISIAE | Descriptor: | 5-(6-D-RIBITYLAMINO-2,4-DIHYDROXYPYRIMIDIN-5-YL)-1-PENTYL-PHOSPHONIC ACID, LUMAZINE SYNTHASE | Authors: | Meining, W, Mortl, S, Fischer, M, Cushman, M, Bacher, A, Ladenstein, R. | Deposit date: | 2000-03-02 | Release date: | 2001-03-02 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The atomic structure of pentameric lumazine synthase from Saccharomyces cerevisiae at 1.85 A resolution reveals the binding mode of a phosphonate intermediate analogue. J.Mol.Biol., 299, 2000
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6RGT
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![BU of 6rgt by Molmil](/molmil-images/mine/6rgt) | Crystal structure of the cofactor-free Aspergillus flavus urate oxidase T57A variant anaerobically complexed with 9-methyl uric acid | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 9-METHYL URIC ACID, ... | Authors: | Bui, S, Lowden, S.R.J, Steiner, R.A. | Deposit date: | 2019-04-17 | Release date: | 2020-05-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of the cofactor-free Aspergillus flavus urate oxidase T57A variant anaerobically complexed with 9-methyl uric acid To Be Published
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5WJD
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![BU of 5wjd by Molmil](/molmil-images/mine/5wjd) | Crystal structure of Naa80 bound to acetyl-CoA | Descriptor: | ACETYL COENZYME *A, CG8481, isoform B, ... | Authors: | Goris, M, Magin, R.S, Marmorstein, R, Arnesen, T. | Deposit date: | 2017-07-21 | Release date: | 2018-03-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Structural determinants and cellular environment define processed actin as the sole substrate of the N-terminal acetyltransferase NAA80. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1MNT
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![BU of 1mnt by Molmil](/molmil-images/mine/1mnt) | SOLUTION STRUCTURE OF DIMERIC MNT REPRESSOR (1-76) | Descriptor: | MNT REPRESSOR | Authors: | Burgering, M.J.M, Boelens, R, Gilbert, D.E, Breg, J.N, Knight, K.L, Sauer, R.T, Kaptein, R. | Deposit date: | 1994-06-28 | Release date: | 1994-09-30 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of dimeric Mnt repressor (1-76). Biochemistry, 33, 1994
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2RC4
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![BU of 2rc4 by Molmil](/molmil-images/mine/2rc4) | Crystal Structure of the HAT domain of the human MOZ protein | Descriptor: | ACETYL COENZYME *A, Histone acetyltransferase MYST3, ZINC ION | Authors: | Holbert, M.A, Sikorski, T, Snowflack, D, Marmorstein, R. | Deposit date: | 2007-09-19 | Release date: | 2007-11-13 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The human monocytic leukemia zinc finger histone acetyltransferase domain contains DNA-binding activity implicated in chromatin targeting. J.Biol.Chem., 282, 2007
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4UT3
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![BU of 4ut3 by Molmil](/molmil-images/mine/4ut3) | X-ray structure of the human PP1 gamma catalytic subunit treated with hydrogen peroxide | Descriptor: | MANGANESE (II) ION, PHOSPHATE ION, SERINE/THREONINE-PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUBUNIT | Authors: | Zeh Silva, M, Kopec, J, Fotinou, D, Steiner, R.A. | Deposit date: | 2014-07-17 | Release date: | 2015-07-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Targeted Redox Inhibition of Protein Phosphatase 1 by Nox4 Regulates Eif2Alpha-Mediated Stress Signaling. Embo J., 35, 2016
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4UT2
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![BU of 4ut2 by Molmil](/molmil-images/mine/4ut2) | X-ray structure of the human PP1 gamma catalytic subunit treated with ascorbate | Descriptor: | MANGANESE (II) ION, PHOSPHATE ION, SERINE/THREONINE-PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUBUNIT | Authors: | Kopec, J, Zeh Silva, M, Fotinou, C, Steiner, R.A. | Deposit date: | 2014-07-17 | Release date: | 2015-07-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Targeted Redox Inhibition of Protein Phosphatase 1 by Nox4 Regulates Eif2Alpha-Mediated Stress Signaling. Embo J., 35, 2016
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7MX2
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![BU of 7mx2 by Molmil](/molmil-images/mine/7mx2) | |
4UOW
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![BU of 4uow by Molmil](/molmil-images/mine/4uow) | Crystal structure of the titin M10-Obscurin Ig domain 1 complex | Descriptor: | CHLORIDE ION, Obscurin, SODIUM ION, ... | Authors: | Pernigo, S, Fukuzawa, A, Gautel, M, Steiner, R.A. | Deposit date: | 2014-06-10 | Release date: | 2014-12-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | The Crystal Structure of the Human Titin:Obscurin Complex Reveals a Conserved Yet Specific Muscle M-Band Zipper Module. J.Mol.Biol., 427, 2015
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5ICV
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![BU of 5icv by Molmil](/molmil-images/mine/5icv) | Crystal structure of human NatF (hNaa60) bound to a bisubstrate analogue | Descriptor: | MET-LYS-ALA-VAL-LIG, N-alpha-acetyltransferase 60, [5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)furan-2-yl]methyl (3R)-4-{[3-({(E)-2-[(2,2-dihydroxyethyl)sulfanyl]ethenyl}amino)-3-oxopropyl]amino}-3-hydroxy-2,2-dimethyl-4-oxobutyl dihydrogen diphosphate | Authors: | Stove, S.I, Magin, R.S, Marmorstein, R, Arnesen, T. | Deposit date: | 2016-02-23 | Release date: | 2016-06-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Crystal Structure of the Golgi-Associated Human N alpha-Acetyltransferase 60 Reveals the Molecular Determinants for Substrate-Specific Acetylation. Structure, 24, 2016
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