2OD9

Structural Basis for Nicotinamide Inhibition and Base Exchange in Sir2 Enzymes

Summary for 2OD9

Entry DOI	10.2210/pdb2od9/pdb
Related	1SZC 1SZD 2OD2 2OD7
Descriptor	NAD-dependent deacetylase HST2, H4 peptide, ZINC ION, ... (6 entities in total)
Functional Keywords	zn binding protein, rossmann fold, hydrolase
Biological source	Saccharomyces cerevisiae (baker's yeast)
Cellular location	Cytoplasm: P53686
Total number of polymer chains	2
Total formula weight	37135.62
Authors	Marmorstein, R.,Sanders, B.D. (deposition date: 2006-12-21, release date: 2007-02-27, Last modification date: 2023-11-15)
Primary citation	Sanders, B.D.,Zhao, K.,Slama, J.T.,Marmorstein, R. Structural basis for nicotinamide inhibition and base exchange in sir2 enzymes. Mol.Cell, 25:463-472, 2007 Cited by PubMed: 17289592 DOI: 10.1016/j.molcel.2006.12.022 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation