1SZD
Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD+-dependent Sir2 histone/protein deacetylases
Summary for 1SZD
Entry DOI | 10.2210/pdb1szd/pdb |
Related | 1Q14 1Q17 1Q1A 1SZC |
Descriptor | NAD-dependent deacetylase HST2, Histone H4 peptide, CHLORIDE ION, ... (7 entities in total) |
Functional Keywords | hst2, sir2, sirtuin, histone deacetylase, protein deacetylase, gene regulation |
Biological source | Saccharomyces cerevisiae (baker's yeast) More |
Cellular location | Nucleus (Potential): P53686 Nucleus: P02309 |
Total number of polymer chains | 2 |
Total formula weight | 35610.30 |
Authors | Zhao, K.,Harshaw, R.,Chai, X.,Marmorstein, R. (deposition date: 2004-04-05, release date: 2004-06-15, Last modification date: 2023-11-15) |
Primary citation | Zhao, K.,Harshaw, R.,Chai, X.,Marmorstein, R. Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases. Proc.Natl.Acad.Sci.Usa, 101:8563-8568, 2004 Cited by PubMed: 15150415DOI: 10.1073/pnas.0401057101 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
Download full validation report