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PDB: 57 件

5COM
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BU of 5com by Molmil
Crystal structure of Uncharacterized Protein Q187F5 from Clostridium difficile 630
分子名称: D(-)-TARTARIC ACID, Putative conjugative transposon protein Tn1549-like, CTn5-Orf2, ...
著者Taylor, J.D, Taylor, G, Matthews, S.J.
登録日2015-07-20
公開日2016-02-03
最終更新日2016-03-02
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structures of the DfsB Protein Family Suggest a Cationic, Helical Sibling Lethal Factor Peptide.
J.Mol.Biol., 428, 2016
5CIV
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BU of 5civ by Molmil
Sibling Lethal Factor Precursor - DfsB
分子名称: Sibling bacteriocin
著者Taylor, J.D, Matthews, S.J.
登録日2015-07-13
公開日2016-02-03
最終更新日2016-03-02
実験手法X-RAY DIFFRACTION (1.384 Å)
主引用文献Structures of the DfsB Protein Family Suggest a Cationic, Helical Sibling Lethal Factor Peptide.
J.Mol.Biol., 428, 2016
5COG
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BU of 5cog by Molmil
Crystal structure of Yeast IRC4
分子名称: CHLORIDE ION, IRC4, PHOSPHATE ION, ...
著者Taylor, J.D, Matthews, S.J.
登録日2015-07-20
公開日2016-02-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.613 Å)
主引用文献Structures of the DfsB Protein Family Suggest a Cationic, Helical Sibling Lethal Factor Peptide.
J.Mol.Biol., 428, 2016
5COF
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BU of 5cof by Molmil
Crystal structure of Uncharacterised protein Q1R1X2 from Escherichia coli UTI89
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, CHLORIDE ION, ...
著者Taylor, J.D, Hare, S, Matthews, S.J.
登録日2015-07-20
公開日2016-02-03
最終更新日2016-03-02
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structures of the DfsB Protein Family Suggest a Cationic, Helical Sibling Lethal Factor Peptide.
J.Mol.Biol., 428, 2016
5CQV
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BU of 5cqv by Molmil
Crystal structure of uncharacterized protein Q8DWV2 from Streptococcus agalactiae
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Uncharacterized protein
著者Taylor, J.D, Hare, S, Matthews, S.J.
登録日2015-07-22
公開日2016-02-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of the DfsB Protein Family Suggest a Cationic, Helical Sibling Lethal Factor Peptide.
J.Mol.Biol., 428, 2016
3VFD
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BU of 3vfd by Molmil
Human spastin AAA domain
分子名称: SULFATE ION, Spastin
著者Taylor, J.L, White, S.R, Lauring, B, Kull, F.J.
登録日2012-01-09
公開日2012-05-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.301 Å)
主引用文献Crystal structure of the human spastin AAA domain.
J.Struct.Biol., 179, 2012
2JYQ
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BU of 2jyq by Molmil
NMR structure of the apo v-Src SH2 domain
分子名称: Tyrosine-protein kinase transforming protein Src
著者Taylor, J.D, Ababou, A, Williams, M.A, Ladbury, J.E.
登録日2007-12-17
公開日2008-06-24
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Structure, dynamics, and binding thermodynamics of the v-Src SH2 domain: Implications for drug design
Proteins, 73, 2008
3T1B
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BU of 3t1b by Molmil
Crystal structure of the full-length AphB N100E variant
分子名称: Transcriptional regulator, LysR family
著者Taylor, J.L, De Silva, R.S, Kovacikova, G, Lin, W, Taylor, R.K, Skorupski, K, Kull, F.J.
登録日2011-07-21
公開日2011-11-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The crystal structure of AphB, a virulence gene activator from Vibrio cholerae, reveals residues that influence its response to oxygen and pH.
Mol.Microbiol., 83, 2012
3SZP
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BU of 3szp by Molmil
Full-length structure of the Vibrio cholerae virulence activator, AphB, a member of the LTTR protein family
分子名称: Transcriptional regulator, LysR family
著者Taylor, J.L, De Silva, R.S, Kovacikova, G, Lin, W, Taylor, R.K, Skorupski, K, Kull, F.J.
登録日2011-07-19
公開日2011-11-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.202 Å)
主引用文献The crystal structure of AphB, a virulence gene activator from Vibrio cholerae, reveals residues that influence its response to oxygen and pH.
Mol.Microbiol., 83, 2012
2Y2T
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BU of 2y2t by Molmil
E. coli CsgC in reduced form
分子名称: CURLI PRODUCTION PROTEIN CSGC
著者Taylor, J.D, Salgado, P.S, Cota, E, Matthews, S.J.
登録日2010-12-16
公開日2011-09-21
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Atomic Resolution Insights Into Curli Fiber Biogenesis.
Structure, 19, 2011
2Y2Y
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BU of 2y2y by Molmil
Oxidised form of E. coli CsgC
分子名称: ACETATE ION, CURLI PRODUCTION PROTEIN CSGC
著者Taylor, J.D, Salgado, P.S, Constable, S.C, Cota, E, Mathews, S.J.
登録日2010-12-16
公開日2011-09-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Atomic Resolution Insights Into Curli Fiber Biogenesis.
Structure, 19, 2011
1LD8
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BU of 1ld8 by Molmil
Co-crystal structure of Human Farnesyltransferase with farnesyldiphosphate and inhibitor compound 49
分子名称: (20S)-19,20,21,22-TETRAHYDRO-19-OXO-5H-18,20-ETHANO-12,14-ETHENO-6,10-METHENO-18H-BENZ[D]IMIDAZO[4,3-K][1,6,9,12]OXATRI AZA-CYCLOOCTADECOSINE-9-CARBONITRILE, ACETIC ACID, FARNESYL DIPHOSPHATE, ...
著者Taylor, J.S, Terry, K.L, Beese, L.S.
登録日2002-04-08
公開日2002-06-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献3-Aminopyrrolidinone farnesyltransferase inhibitors: design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency.
J.Med.Chem., 45, 2002
1LD7
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BU of 1ld7 by Molmil
Co-crystal structure of Human Farnesyltransferase with farnesyldiphosphate and inhibitor compound 66
分子名称: (20S)-19,20,22,23-TETRAHYDRO-19-OXO-5H,21H-18,20-ETHANO-12,14-ETHENO-6,10-METHENOBENZ[D]IMIDAZO[4,3-L][1,6,9,13]OXATRIA ZACYCLONOADECOSINE-9-CARBONITRILE, FARNESYL DIPHOSPHATE, ZINC ION, ...
著者Taylor, J.S, Terry, K.L, Beese, L.S.
登録日2002-04-08
公開日2002-06-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献3-Aminopyrrolidinone farnesyltransferase inhibitors: design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency.
J.Med.Chem., 45, 2002
1N4R
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BU of 1n4r by Molmil
Protein Geranylgeranyltransferase type-I Complexed with a Geranylgeranylated KKKSKTKCVIL Peptide Product
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Fusion protein consisting of transforming protein p21b and Ras related protein Rap-2b, ...
著者Taylor, J.S, Reid, T.S, Casey, P.J, Beese, L.S.
登録日2002-11-01
公開日2003-11-18
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of mammalian protein geranylgeranyltransferase type-I
EMBO J., 22, 2003
1N4P
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BU of 1n4p by Molmil
Protein Geranylgeranyltransferase type-I Complexed with Geranylgeranyl Diphosphate
分子名称: CHLORIDE ION, Fusion protein consisting of transforming protein p21b and Ras related protein Rap-2b, GERAN-8-YL GERAN, ...
著者Taylor, J.S, Reid, T.S, Casey, P.J, Beese, L.S.
登録日2002-11-01
公開日2003-11-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure of mammalian protein geranylgeranyltransferase type-I
EMBO J., 22, 2003
1N4Q
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BU of 1n4q by Molmil
Protein Geranylgeranyltransferase type-I Complexed with a GGPP Analog and a KKKSKTKCVIL Peptide
分子名称: 2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE, CHLORIDE ION, Fusion protein consisting of transforming protein p21b and Ras related protein Rap-2b, ...
著者Taylor, J.S, Reid, T.S, Casey, P.J, Beese, L.S.
登録日2002-11-01
公開日2003-11-18
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of mammalian protein geranylgeranyltransferase type-I
EMBO J., 22, 2003
1N4S
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BU of 1n4s by Molmil
Protein Geranylgeranyltransferase type-I Complexed with GGPP and a Geranylgeranylated KKKSKTKCVIL Peptide Product
分子名称: CHLORIDE ION, Fusion protein consisting of transforming protein p21b and Ras related protein Rap-2b, GERAN-8-YL GERAN, ...
著者Taylor, J.S, Reid, T.S, Casey, P.J, Beese, L.S.
登録日2002-11-01
公開日2003-11-18
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of mammalian protein geranylgeranyltransferase type-I
EMBO J., 22, 2003
8TH5
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BU of 8th5 by Molmil
Crystal Structure of the G3BP1 NTF2-like domain bound to the IDR1 of SARS-CoV-2 nucleocapsid protein P13L mutant
分子名称: Nucleoprotein, Ras GTPase-activating protein-binding protein 1
著者Hughes, M.P, Taylor, J.P, Yang, Z.
登録日2023-07-13
公開日2024-03-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity.
Cell Rep, 43, 2024
8TH1
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BU of 8th1 by Molmil
Crystal Structure of the G3BP1 NTF2-like domain bound to the IDR1 of SARS-CoV-2 nucleocapsid protein D3L mutant
分子名称: Nucleoprotein, Ras GTPase-activating protein-binding protein 1
著者Hughes, M.P, Taylor, J.P, Yang, Z.
登録日2023-07-13
公開日2023-12-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity.
Cell Rep, 43, 2024
8TH7
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BU of 8th7 by Molmil
Crystal Structure of the G3BP1 NTF2-like domain bound to the Caprin1 peptide
分子名称: Caprin-1, Ras GTPase-activating protein-binding protein 1
著者Hughes, M.P, Taylor, J.P, Yang, Z.
登録日2023-07-14
公開日2024-03-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity.
Cell Rep, 43, 2024
8TH6
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BU of 8th6 by Molmil
Crystal Structure of the G3BP1 NTF2-like domain bound to USP10 peptide
分子名称: 1,2-ETHANEDIOL, Ras GTPase-activating protein-binding protein 1, Ubiquitin carboxyl-terminal hydrolase 10
著者Hughes, M.P, Taylor, J.P, Yang, Z.
登録日2023-07-14
公開日2024-03-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity.
Cell Rep, 43, 2024
8V1L
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BU of 8v1l by Molmil
Crystal structure of the NTF2L domain of human G3BP1 in complex with small molecule
分子名称: N-[(2S)-2-fluoro-4,4-dimethylpentanoyl]-3-hydroxy-L-valyl-(betaS)-beta-methyl-L-phenylalanyl-D-alanyl-N-benzyl-N,O-dimethyl-L-homoserinamide, Ras GTPase-activating protein-binding protein 1
著者Hughes, M.P, Taylor, J.P.
登録日2023-11-20
公開日2024-02-14
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Identification of small molecule inhibitors of G3BP-driven stress granule formation.
J.Cell Biol., 223, 2024
6NZV
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BU of 6nzv by Molmil
Crystal structure of HCV NS3/4A protease in complex with compound 12
分子名称: (1aR,5S,8S,9S,10R,22aR)-5-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}cyclopropyl]-9-ethyl-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxamide, HCV NS3/4A protease, SULFATE ION, ...
著者Appleby, T.C, Taylor, J.G.
登録日2019-02-14
公開日2019-07-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Discovery of the pan-genotypic hepatitis C virus NS3/4A protease inhibitor voxilaprevir (GS-9857): A component of Vosevi®.
Bioorg.Med.Chem.Lett., 29, 2019
6OZX
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BU of 6ozx by Molmil
Wild type GapR crystal structure 1 from C. crescentus
分子名称: UPF0335 protein CC_3319
著者Tarry, M, Harmel, C, Taylor, J.A, Marczynski, G.T, Schmeing, T.M.
登録日2019-05-16
公開日2019-11-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.851 Å)
主引用文献Structures of GapR reveal a central channel which could accommodate B-DNA.
Sci Rep, 9, 2019
6OZY
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BU of 6ozy by Molmil
Wild type GapR crystal structure 2 from C. crescentus
分子名称: CADMIUM ION, UPF0335 protein CC_3319
著者Tarry, M, Harmel, C, Taylor, J.A, Marczynski, G.T, Schmeing, T.M.
登録日2019-05-16
公開日2019-11-27
最終更新日2021-09-22
実験手法X-RAY DIFFRACTION (2.014 Å)
主引用文献Structures of GapR reveal a central channel which could accommodate B-DNA.
Sci Rep, 9, 2019

 

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