8T6P
 
 | | SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 2 bp R-loop | | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | | Deposit date: | 2023-06-16 | | Release date: | 2024-05-01 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
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8T7S
 | | SpRYmer bound to NAC PAM DNA | | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, NTS, ... | | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | | Deposit date: | 2023-06-21 | | Release date: | 2024-05-01 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.01 Å) | | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
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8T6X
 | | SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 18 bp R-loop | | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, NTS, ... | | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | | Deposit date: | 2023-06-19 | | Release date: | 2024-05-01 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.08 Å) | | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
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8T79
 | | SpRY-Cas9:gRNA complex bound to non-target DNA with 10 bp R-loop | | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | | Deposit date: | 2023-06-20 | | Release date: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.04 Å) | | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
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8D49
 | | Structure of Cas12a2 binary complex | | Descriptor: | OrfB_Zn_ribbon domain-containing protein, RNA (26-MER) | | Authors: | Bravo, J.P.K, Taylor, D.W. | | Deposit date: | 2022-06-01 | | Release date: | 2023-01-18 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | RNA targeting unleashes indiscriminate nuclease activity of CRISPR-Cas12a2.
Nature, 613, 2023
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8D4A
 | | Cas12a2 quaternary complex | | Descriptor: | DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ... | | Authors: | Bravo, J.P.K, Taylor, D.W. | | Deposit date: | 2022-06-01 | | Release date: | 2023-01-18 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.74 Å) | | Cite: | RNA targeting unleashes indiscriminate nuclease activity of CRISPR-Cas12a2.
Nature, 613, 2023
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8D4B
 | | Structure of Cas12a2 ternary complex | | Descriptor: | OrfB_Zn_ribbon domain-containing protein, RNA (28-MER), RNA (41-MER) | | Authors: | Bravo, J.P.K, Taylor, D.W. | | Deposit date: | 2022-06-01 | | Release date: | 2023-01-18 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.92 Å) | | Cite: | RNA targeting unleashes indiscriminate nuclease activity of CRISPR-Cas12a2.
Nature, 613, 2023
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8DFS
 | | type I-C Cascade bound to AcrIF2 | | Descriptor: | Anti-CRISPR protein 30, CRISPR-associated protein, CT1133 family, ... | | Authors: | O'Brien, R.E, Bravo, J.P.K, Ramos, D, Hibshman, G.N, Wright, J.T, Taylor, D.W. | | Deposit date: | 2022-06-22 | | Release date: | 2023-02-22 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural snapshots of R-loop formation by a type I-C CRISPR Cascade.
Mol.Cell, 83, 2023
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8DFO
 | | type I-C Cascade bound to AcrIC4 | | Descriptor: | AcrIC4, CRISPR-associated protein, CT1133 family, ... | | Authors: | O'Brien, R.E, Bravo, J.P.K, Ramos, D, Hibshman, G.N, Wright, J.T, Taylor, D.W. | | Deposit date: | 2022-06-22 | | Release date: | 2023-02-15 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural snapshots of R-loop formation by a type I-C CRISPR Cascade.
Mol.Cell, 83, 2023
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8DFA
 | | type I-C Cascade bound to ssDNA target | | Descriptor: | CRISPR-associated protein, CT1133 family, TM1801 family, ... | | Authors: | O'Brien, R.E, Bravo, J.P.K, Ramos, D, Hibshman, G.N, Wright, J.T, Taylor, D.W. | | Deposit date: | 2022-06-21 | | Release date: | 2023-02-22 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural snapshots of R-loop formation by a type I-C CRISPR Cascade.
Mol.Cell, 83, 2023
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8DEJ
 | | D. vulgaris type I-C Cascade bound to dsDNA target | | Descriptor: | CRISPR-associated protein, CT1133 family, TM1801 family, ... | | Authors: | O'Brien, R.E, Bravo, J.P.K, Ramos, D, Hibshman, G.N, Wright, J.T, Taylor, D.W. | | Deposit date: | 2022-06-20 | | Release date: | 2023-02-22 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.86 Å) | | Cite: | Structural snapshots of R-loop formation by a type I-C CRISPR Cascade.
Mol.Cell, 83, 2023
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8DEX
 | | type I-C Cascade | | Descriptor: | CRISPR-associated protein, CT1133 family, TM1801 family, ... | | Authors: | O'Brien, R.E, Bravo, J.P.K, Ramos, D, Hibshman, G.N, Wright, J.T, Taylor, D.W. | | Deposit date: | 2022-06-21 | | Release date: | 2023-02-15 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structural snapshots of R-loop formation by a type I-C CRISPR Cascade.
Mol.Cell, 83, 2023
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