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PDB: 140 results

4O21
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Product complex of metal-free PKAc, ATP-gamma-S and SP20.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Thio-phosphorylated peptide pSP20, cAMP-dependent protein kinase catalytic subunit alpha
Authors:Das, A, Kovalevsky, A.Y, Gerlits, O, Langan, P, Heller, W.T, Keshwani, M, Taylor, S.
Deposit date:2013-12-16
Release date:2014-05-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Metal-Free cAMP-Dependent Protein Kinase Can Catalyze Phosphoryl Transfer.
Biochemistry, 53, 2014
1FMO
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BU of 1fmo by Molmil
CRYSTAL STRUCTURE OF A POLYHISTIDINE-TAGGED RECOMBINANT CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE COMPLEXED WITH THE PEPTIDE INHIBITOR PKI(5-24) AND ADENOSINE
Descriptor: ADENOSINE, CAMP-DEPENDENT PROTEIN KINASE, HEAT STABLE RABBIT SKELETAL MUSCLE INHIBITOR PROTEIN
Authors:Narayana, N, Cox, S, Shaltiel, S, Taylor, S.S, Xuong, N.-H.
Deposit date:1997-07-08
Release date:1998-01-14
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a polyhistidine-tagged recombinant catalytic subunit of cAMP-dependent protein kinase complexed with the peptide inhibitor PKI(5-24) and adenosine.
Biochemistry, 36, 1997
4MX3
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BU of 4mx3 by Molmil
Crystal Structure of PKA RIalpha Homodimer
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, cAMP-dependent protein kinase type I-alpha regulatory subunit
Authors:Bruystens, J.G.H, Wu, J, Fortezzo, A, Kornev, A.P, Blumenthal, D.A, Taylor, S.S.
Deposit date:2013-09-25
Release date:2014-01-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.88 Å)
Cite:PKA RI alpha Homodimer Structure Reveals an Intermolecular Interface with Implications for Cooperative cAMP Binding and Carney Complex Disease.
Structure, 22, 2014
3QAM
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BU of 3qam by Molmil
Crystal Structure of Glu208Ala mutant of catalytic subunit of cAMP-dependent protein kinase
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein kinase inhibitor, ...
Authors:Yang, J, Wu, J, Steichen, J, Taylor, S.S.
Deposit date:2011-01-11
Release date:2011-12-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:A conserved Glu-Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold.
J.Mol.Biol., 415, 2012
3QAL
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BU of 3qal by Molmil
Crystal Structure of Arg280Ala mutant of Catalytic subunit of cAMP-dependent Protein Kinase
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein kinase inhibitor, ...
Authors:Yang, J, Wu, J, Steichen, J, Taylor, S.S.
Deposit date:2011-01-11
Release date:2011-12-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A conserved Glu-Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold.
J.Mol.Biol., 415, 2012
3OF1
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BU of 3of1 by Molmil
Crystal Structure of Bcy1, the Yeast Regulatory Subunit of PKA
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, cAMP-dependent protein kinase regulatory subunit
Authors:Rinaldi, J, Wu, J, Yang, J, Ralston, C.Y, Sankaran, B, Moreno, S, Taylor, S.S.
Deposit date:2010-08-13
Release date:2010-12-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structure of Yeast Regulatory Subunit: A Glimpse into the Evolution of PKA Signaling.
Structure, 18, 2010
3O7L
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BU of 3o7l by Molmil
Crystal Structure of phospholamban (1-19):PKA C-subunit:AMP-PNP:Mg2+ complex
Descriptor: Cardiac phospholamban, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ...
Authors:Cheng, C.Y, Taylor, S.S.
Deposit date:2010-07-30
Release date:2010-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Dynamics connect substrate recognition to catalysis in protein kinase A.
Nat.Chem.Biol., 6, 2010
2KWF
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BU of 2kwf by Molmil
The structure of E-protein activation domain 1 bound to the KIX domain of CBP/p300 elucidates leukemia induction by E2A-PBX1
Descriptor: CREB-binding protein, Transcription factor 4
Authors:Denis, C.M, Chitayat, S, Plevin, M.J, Liu, S, Spencer, H.L, Ikura, M, LeBrun, D.P, Smith, S.P.
Deposit date:2010-04-08
Release date:2011-07-20
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:The structure of E-protein activation domain 1 bound to the KIX domain of CBP/p300 elucidates leukemia induction by E2A-PBX1
To be Published
4DFY
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BU of 4dfy by Molmil
Crystal structure of R194A mutant of cAMP-dependent protein kinase with unphosphorylated activation loop
Descriptor: cAMP-dependent protein kinase catalytic subunit alpha
Authors:Steichen, J.M, Kuchinskas, M, Yang, J, Taylor, S.S.
Deposit date:2012-01-24
Release date:2012-02-15
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.997 Å)
Cite:Structural basis for the regulation of protein kinase a by activation loop phosphorylation.
J.Biol.Chem., 287, 2012
2M1U
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BU of 2m1u by Molmil
Solution structure of the small dictyostelium discoideium myosin light chain mlcb provides insights into iq-motif recognition of class i myosin myo1b
Descriptor: myosin light chain MlcB
Authors:Liburd, J, Chitayat, S, Crawley, S.W, Denis, C.M, Cote, G.P, Smith, S.P.
Deposit date:2012-12-06
Release date:2013-12-11
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of the small Dictyostelium discoideum myosin light chain MlcB provides insights into MyoB IQ motif recognition.
J.Biol.Chem., 289, 2014
2M8U
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Solution structure of the Dictyostelium discodieum Myosin Light Chain, MlcC
Descriptor: Myosin Light Chain, MlcC
Authors:Liburd, J.D, Miller, E, Langelaan, D, Chitayat, S, Crawley, S.W, Cote, G.P, Smith, S.P.
Deposit date:2013-05-28
Release date:2014-12-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of the Single-lobe Myosin Light Chain C in Complex with the Light Chain-binding Domains of Myosin-1C Provides Insights into Divergent IQ Motif Recognition.
J.Biol.Chem., 291, 2016
3PVB
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Crystal structure of (73-244)RIa:C holoenzyme of cAMP-dependent Protein kinase
Descriptor: GLYCEROL, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Boettcher, A.J, Wu, J, Kim, C, Yang, J, Bruystens, J, Cheung, N, Pennypacker, J.K, Blumenthal, D.A, Kornev, A.P, Taylor, S.S.
Deposit date:2010-12-06
Release date:2011-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal structure of (73-244)RIa:C holoenzyme of cAMP-dependent Protein kinase
Structure, 19, 2011
3TNP
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BU of 3tnp by Molmil
Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme
Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type II-beta regulatory subunit
Authors:Zhang, P, Smith-Nguyen, E.V, Keshwani, M.M, Deal, M.S, Kornev, A.P, Taylor, S.S.
Deposit date:2011-09-01
Release date:2012-02-01
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and allostery of the PKA RIIbeta tetrameric holoenzyme
Science, 335, 2012
2LS6
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BU of 2ls6 by Molmil
Solution NMR Structure of a Non-canonical galactose-binding CBM32 from Clostridium perfringens
Descriptor: Hyaluronoglucosaminidase
Authors:Grondin, J.M, Chitayat, S, Ficko-Blean, E, Boraston, A.B, Smith, S.P.
Deposit date:2012-04-20
Release date:2013-05-01
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:An unusual mode of galactose recognition by a family 32 carbohydrate-binding module.
J.Mol.Biol., 426, 2014
2CPK
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BU of 2cpk by Molmil
CRYSTAL STRUCTURE OF THE CATALYTIC SUBUNIT OF CYCLIC ADENOSINE MONOPHOSPHATE-DEPENDENT PROTEIN KINASE
Descriptor: PEPTIDE INHIBITOR 20-MER, cAMP-DEPENDENT PROTEIN KINASE, CATALYTIC SUBUNIT
Authors:Knighton, D.R, Zheng, J, Teneyck, L.F, Ashford, V.A, Xuong, N.-H, Taylor, S.S, Sowadski, J.M.
Deposit date:1992-10-21
Release date:1993-01-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase.
Science, 253, 1991
1J3H
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BU of 1j3h by Molmil
Crystal structure of apoenzyme cAMP-dependent protein kinase catalytic subunit
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, cAMP-dependent protein kinase, alpha-catalytic subunit
Authors:Akamine, P, Madhusudan, Wu, J, Xuong, N.H, Ten Eyck, L.F, Taylor, S.S.
Deposit date:2003-01-31
Release date:2003-03-04
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Dynamic Features of cAMP-dependent Protein Kinase Revealed by Apoenzyme Crystal Structure
J.Mol.Biol., 327, 2003
3SHR
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BU of 3shr by Molmil
Crystal Structure of cGMP-dependent Protein Kinase Reveals Novel Site of Interchain Communication
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SULFATE ION, cGMP-dependent protein kinase 1
Authors:Osborne, B.W, Wu, J, Taylor, S.S, Dostmann, W.R.
Deposit date:2011-06-16
Release date:2011-09-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of cGMP-Dependent Protein Kinase Reveals Novel Site of Interchain Communication.
Structure, 19, 2011
3TNQ
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BU of 3tnq by Molmil
Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein kinase, ...
Authors:Zhang, P, Smith-Nguyen, E.V, Keshwani, M.M, Deal, M.S, Kornev, A.P, Taylor, S.S.
Deposit date:2011-09-01
Release date:2012-02-01
Last modified:2012-09-26
Method:X-RAY DIFFRACTION (3.097 Å)
Cite:Structure and allostery of the PKA RIIbeta tetrameric holoenzyme
Science, 335, 2012
1JLU
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BU of 1jlu by Molmil
Crystal Structure of the Catalytic Subunit of cAMP-dependent Protein Kinase Complexed with a Phosphorylated Substrate Peptide and Detergent
Descriptor: AMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR, ...
Authors:Madhusudan, Trafny, E.A, Xuong, N.-H, Adams, J.A, Ten Eyck, L.F, Taylor, S.S, Sowadski, J.M.
Deposit date:2001-07-16
Release date:2001-08-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:cAMP-dependent protein kinase: crystallographic insights into substrate recognition and phosphotransfer.
Protein Sci., 3, 1994
2MH0
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BU of 2mh0 by Molmil
Solution NMR structure of the p300 Taz2:ETAD1 complex
Descriptor: Histone acetyltransferase p300, Transcription factor E2-alpha
Authors:Langelaan, D.N, Smith, S.P, Chitayat, S.
Deposit date:2013-11-12
Release date:2014-11-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural insights into TAZ2 domain-mediated CBP/p300 recruitment by transactivation domain 1 of the lymphopoietic transcription factor E2A.
J.Biol.Chem., 295, 2020
5VJU
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BU of 5vju by Molmil
De Novo Photosynthetic Reaction Center Protein Variant Equipped with His-Tyr H-bond, Heme B, and Cd(II) ions
Descriptor: CADMIUM ION, PROTOPORPHYRIN IX CONTAINING FE, Reaction Center Maquette Leu71His variant
Authors:Ennist, N.M, Stayrook, S.E, Dutton, P.L, Moser, C.C.
Deposit date:2017-04-19
Release date:2018-04-25
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:De novo protein design of photochemical reaction centers.
Nat Commun, 13, 2022
2LTJ
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BU of 2ltj by Molmil
Conformational analysis of StrH, the surface-attached exo- beta-D-N-acetylglucosaminidase from Streptococcus pneumoniae
Descriptor: Beta-N-acetylhexosaminidase
Authors:Pluvinage, B, Chitayat, S, Ficko-Blean, E, Abbott, D, Kunjachen, J, Grondin, J, Spencer, H, Smith, S, Boraston, A.
Deposit date:2012-05-28
Release date:2012-11-28
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Conformational analysis of StrH, the surface-attached exo-beta-D-N-acetylglucosaminidase from Streptococcus pneumoniae.
J.Mol.Biol., 425, 2013
5VJT
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BU of 5vjt by Molmil
De Novo Photosynthetic Reaction Center Protein Equipped with Heme B and Zn(II) cations
Descriptor: CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, Reaction Center Maquette, ...
Authors:Ennist, N.M, Stayrook, S.E, Dutton, P.L, Moser, C.C.
Deposit date:2017-04-19
Release date:2018-04-25
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:De novo protein design of photochemical reaction centers.
Nat Commun, 13, 2022
5VJS
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BU of 5vjs by Molmil
De Novo Photosynthetic Reaction Center Protein Equipped with Heme B, a synthetic Zn porphyrin, and Zn(II) cations
Descriptor: CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, Reaction Center Maquette, ...
Authors:Ennist, N.M, Dutton, P.L, Stayrook, S.E, Moser, C.C.
Deposit date:2017-04-19
Release date:2018-04-25
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:De novo protein design of photochemical reaction centers.
Nat Commun, 13, 2022
1Y47
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BU of 1y47 by Molmil
Structural studies of designed alpha-helical hairpins
Descriptor: CADMIUM ION, dueferri (DF2)
Authors:Lahr, S.J, Engel, D.E, Stayrook, S.E, Maglio, O, North, B, Geremia, S, Lombardi, A, DeGrado, W.F.
Deposit date:2004-11-30
Release date:2005-03-22
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Analysis and design of turns in alpha-helical hairpins
J.Mol.Biol., 346, 2005

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