1CKH
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![BU of 1ckh by Molmil](/molmil-images/mine/1ckh) | T70V MUTANT HUMAN LYSOZYME | Descriptor: | PROTEIN (LYSOZYME) | Authors: | Takano, K, Yamagata, Y, Funahashi, J, Yutani, K. | Deposit date: | 1999-04-22 | Release date: | 1999-04-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Contribution of intra- and intermolecular hydrogen bonds to the conformational stability of human lysozyme(,). Biochemistry, 38, 1999
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1CKD
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![BU of 1ckd by Molmil](/molmil-images/mine/1ckd) | T43V MUTANT HUMAN LYSOZYME | Descriptor: | PROTEIN (LYSOZYME), SODIUM ION | Authors: | Takano, K, Yamagata, Y, Funahashi, J, Yutani, K. | Deposit date: | 1999-04-22 | Release date: | 1999-04-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Contribution of intra- and intermolecular hydrogen bonds to the conformational stability of human lysozyme(,). Biochemistry, 38, 1999
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1EQ5
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![BU of 1eq5 by Molmil](/molmil-images/mine/1eq5) | CRYSTAL STRUCTURES OF SALT BRIDGE MUTANTS OF HUMAN LYSOZYME | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Takano, K, Tsuchimori, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-04-03 | Release date: | 2000-04-19 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Contribution of salt bridges near the surface of a protein to the conformational stability. Biochemistry, 39, 2000
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1EQE
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![BU of 1eqe by Molmil](/molmil-images/mine/1eqe) | CRYSTAL STRUCTURES OF SALT BRIDGE MUTANTS OF HUMAN LYSOZYME | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Takano, K, Tsuchimori, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-04-04 | Release date: | 2000-04-19 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Contribution of salt bridges near the surface of a protein to the conformational stability. Biochemistry, 39, 2000
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1WQ5
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![BU of 1wq5 by Molmil](/molmil-images/mine/1wq5) | Crystal structure of tryptophan synthase alpha-subunit from Escherichia coli | Descriptor: | GLYCEROL, SULFATE ION, Tryptophan synthase alpha chain | Authors: | Nishio, K, Morimoto, Y, Ishizuka, M, Ogasahara, K, Yutani, K, Tsukihara, T, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-09-22 | Release date: | 2005-02-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Conformational Changes in the alpha-Subunit Coupled to Binding of the beta(2)-Subunit of Tryptophan Synthase from Escherichia coli: Crystal Structure of the Tryptophan Synthase alpha-Subunit Alon Biochemistry, 44, 2005
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1EQ4
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![BU of 1eq4 by Molmil](/molmil-images/mine/1eq4) | CRYSTAL STRUCTURES OF SALT BRIDGE MUTANTS OF HUMAN LYSOZYME | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Takano, K, Tsuchimori, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-04-03 | Release date: | 2000-04-19 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Contribution of salt bridges near the surface of a protein to the conformational stability. Biochemistry, 39, 2000
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6QIS
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![BU of 6qis by Molmil](/molmil-images/mine/6qis) | Crystal structure of CAG repeats with synthetic CMBL3a compound (model II) | Descriptor: | CMBL3a, RNA (5'-R(*GP*CP*AP*GP*CP*AP*GP*C)-3'), SULFATE ION | Authors: | Kiliszek, A, Blaszczyk, L, Rypniewski, W, Nakatani, K. | Deposit date: | 2019-01-21 | Release date: | 2019-09-25 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats. Nucleic Acids Res., 47, 2019
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6QIV
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![BU of 6qiv by Molmil](/molmil-images/mine/6qiv) | Crystal structure of seleno-derivative CAG repeats with synthetic CMBL4 compound | Descriptor: | CMBL4, RNA (5'-R(*GP*CP*AP*GP*CP*AP*GP*C)-3') | Authors: | Kiliszek, A, Blaszczyk, L, Rypniewski, W, Nakatani, K. | Deposit date: | 2019-01-21 | Release date: | 2019-09-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats. Nucleic Acids Res., 47, 2019
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6QIQ
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![BU of 6qiq by Molmil](/molmil-images/mine/6qiq) | Crystal structure of seleno-derivative CAG repeats with synthetic CMBL3a compound | Descriptor: | CMBL3a, RNA (5'-R(*GP*CP*AP*G)-D(P*(CSL))-R(P*AP*GP*C)-3') | Authors: | Kiliszek, A, Blaszczyk, L, Rypniewski, W, Micura, R, Nakatani, K. | Deposit date: | 2019-01-21 | Release date: | 2019-09-25 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.519 Å) | Cite: | Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats. Nucleic Acids Res., 47, 2019
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6QIT
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![BU of 6qit by Molmil](/molmil-images/mine/6qit) | Crystal structure of CAG repeats with synthetic CMBL3b compound | Descriptor: | CMBL3a, RNA (5'-R(*GP*CP*AP*GP*CP*AP*GP*C)-3') | Authors: | Kiliszek, A, Blaszczyk, L, Rypniewski, W, Nakatani, K. | Deposit date: | 2019-01-21 | Release date: | 2019-09-25 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.501 Å) | Cite: | Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats. Nucleic Acids Res., 47, 2019
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6QIR
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![BU of 6qir by Molmil](/molmil-images/mine/6qir) | Crystal structure of CAG repeats with synthetic CMBL3a compound (model I) | Descriptor: | CMBL3a, RNA (5'-R(*GP*CP*AP*GP*CP*AP*GP*C)-3') | Authors: | Kiliszek, A, Blaszczyk, L, Rypniewski, W, Nakatani, K. | Deposit date: | 2019-01-21 | Release date: | 2019-09-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.531 Å) | Cite: | Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats. Nucleic Acids Res., 47, 2019
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1V7Y
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![BU of 1v7y by Molmil](/molmil-images/mine/1v7y) | Crystal structure of tryptophan synthase alpha-subunit from Escherichia coli at room temperature | Descriptor: | SULFATE ION, Tryptophan synthase alpha chain | Authors: | Nishio, K, Morimoto, Y, Ishizuka, M, Ogasahara, K, Yutani, K, Tsukihara, T, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-12-25 | Release date: | 2005-02-15 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Conformational Changes in the alpha-Subunit Coupled to Binding of the beta(2)-Subunit of Tryptophan Synthase from Escherichia coli: Crystal Structure of the Tryptophan Synthase alpha-Subunit Alon Biochemistry, 44, 2005
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1X12
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![BU of 1x12 by Molmil](/molmil-images/mine/1x12) | Structure of Mutant Pyrrolidone Carboxyl Peptidase (E192D) from a Hyperthermophile, Pyrococcus furiosus | Descriptor: | Pyrrolidone-carboxylate peptidase | Authors: | Kaushik, J.K, Yamagata, Y, Ogasahara, K, Yutani, K. | Deposit date: | 2005-03-31 | Release date: | 2006-06-13 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Completely buried, non-ion-paired glutamic acid contributes favorably to the conformational stability of pyrrolidone carboxyl peptidases from hyperthermophiles. Biochemistry, 45, 2006
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1X10
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![BU of 1x10 by Molmil](/molmil-images/mine/1x10) | Structure of Mutant Pyrrolidone Carboxyl Peptidase (E192A) from a Hyperthermophile, Pyrococcus furiosus | Descriptor: | Pyrrolidone-carboxylate peptidase | Authors: | Kaushik, J.K, Yamagata, Y, Ogasahara, K, Yutani, K. | Deposit date: | 2005-03-31 | Release date: | 2006-06-13 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Completely buried, non-ion-paired glutamic acid contributes favorably to the conformational stability of pyrrolidone carboxyl peptidases from hyperthermophiles. Biochemistry, 45, 2006
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6IZP
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![BU of 6izp by Molmil](/molmil-images/mine/6izp) | Solution structure of the complex of naphthyridine carbamate dimer and an RNA with UGGAA-UGGAA pentad | Descriptor: | 3-[3-[(7-methyl-1,8-naphthyridin-2-yl)carbamoyloxy]propylamino]propyl ~{N}-(7-methyl-1,8-naphthyridin-2-yl)carbamate, RNA (29-MER) | Authors: | Nagano, K, Shibata, T, Nakatani, K, Kawai, G. | Deposit date: | 2018-12-20 | Release date: | 2019-12-25 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Small molecule targeting r(UGGAA)n disrupts RNA foci and alleviates disease phenotype in Drosophila model Nat Commun, 12, 2021
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1GEZ
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![BU of 1gez by Molmil](/molmil-images/mine/1gez) | BURIED POLAR MUTANT HUMAN LYSOZYME | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-11-30 | Release date: | 2001-04-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Contribution of polar groups in the interior of a protein to the conformational stability. Biochemistry, 40, 2001
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1GF4
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![BU of 1gf4 by Molmil](/molmil-images/mine/1gf4) | BURIED POLAR MUTANT HUMAN LYSOZYME | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-11-30 | Release date: | 2001-04-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Contribution of polar groups in the interior of a protein to the conformational stability. Biochemistry, 40, 2001
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7FCI
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![BU of 7fci by Molmil](/molmil-images/mine/7fci) | human NTCP in complex with YN69083 Fab | Descriptor: | Fab Heavy chain, Fab Light chain, Sodium/bile acid cotransporter | Authors: | Park, J.H, Iwamoto, M, Yun, J.H, Uchikubo-Kamo, T, Son, D, Jin, Z, Yoshida, H, Ohki, M, Ishimoto, N, Mizutani, K, Oshima, M, Muramatsu, M, Wakita, T, Shirouzu, M, Liu, K, Uemura, T, Nomura, N, Iwata, S, Watashi, K, Tame, J.R.H, Nishizawa, T, Lee, W, Park, S.Y. | Deposit date: | 2021-07-14 | Release date: | 2022-05-25 | Last modified: | 2022-07-13 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural insights into the HBV receptor and bile acid transporter NTCP. Nature, 606, 2022
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1JJU
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![BU of 1jju by Molmil](/molmil-images/mine/1jju) | Structure of a Quinohemoprotein Amine Dehydrogenase with a Unique Redox Cofactor and Highly Unusual Crosslinking | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, QUINOHEMOPROTEIN AMINE DEHYDROGENASE, SODIUM ION, ... | Authors: | Datta, S, Mori, Y, Takagi, K, Kawaguchi, K, Chen, Z.-W, Kano, K, Ikeda, T, Okajima, T, Kuroda, S, Tanizawa, K, Mathews, F.S. | Deposit date: | 2001-07-09 | Release date: | 2001-12-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure of a quinohemoprotein amine dehydrogenase with an uncommon redox cofactor and highly unusual crosslinking. Proc.Natl.Acad.Sci.USA, 98, 2001
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1GEV
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![BU of 1gev by Molmil](/molmil-images/mine/1gev) | BURIED POLAR MUTANT HUMAN LYSOZYME | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-11-30 | Release date: | 2001-04-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Contribution of polar groups in the interior of a protein to the conformational stability. Biochemistry, 40, 2001
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1GF5
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![BU of 1gf5 by Molmil](/molmil-images/mine/1gf5) | BURIED POLAR MUTANT HUMAN LYSOZYME | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-11-30 | Release date: | 2001-04-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Contribution of polar groups in the interior of a protein to the conformational stability. Biochemistry, 40, 2001
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1GF7
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![BU of 1gf7 by Molmil](/molmil-images/mine/1gf7) | BURIED POLAR MUTANT HUMAN LYSOZYME | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-11-30 | Release date: | 2001-04-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Contribution of polar groups in the interior of a protein to the conformational stability Biochemistry, 40, 2001
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1GF0
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![BU of 1gf0 by Molmil](/molmil-images/mine/1gf0) | BURIED POLAR MUTANT HUMAN LYSOZYME | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-11-30 | Release date: | 2001-04-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Contribution of polar groups in the interior of a protein to the conformational stability. Biochemistry, 40, 2001
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1GF6
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![BU of 1gf6 by Molmil](/molmil-images/mine/1gf6) | BURIED POLAR MUTANT HUMAN LYSOZYME | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-11-30 | Release date: | 2001-04-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Contribution of polar groups in the interior of a protein to the conformational stability. Biochemistry, 40, 2001
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1GF3
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![BU of 1gf3 by Molmil](/molmil-images/mine/1gf3) | BURIED POLAR MUTANT HUMAN LYSOZYME | Descriptor: | LYSOZYME, SODIUM ION | Authors: | Takano, K, Yamagata, Y, Yutani, K. | Deposit date: | 2000-11-30 | Release date: | 2001-04-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Contribution of polar groups in the interior of a protein to the conformational stability. Biochemistry, 40, 2001
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