5WT9
 
 | | Complex structure of PD-1 and nivolumab-Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy Chain of Nivolumab, Light Chain of Nivolumab, ... | | 著者 | Tan, S, Zhang, H, Chai, Y, Song, H, Tong, Z, Wang, Q, Qi, J, Wong, G, Zhu, X, Liu, W.J, Gao, S, Wang, Z, Shi, Y, Yang, F, Gao, G.F, Yan, J. | | 登録日 | 2016-12-10 | | 公開日 | 2017-02-15 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | | 主引用文献 | An unexpected N-terminal loop in PD-1 dominates binding by nivolumab.
Nat Commun, 8, 2017
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2AW9
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3BN4
 | | Carboxysome Subunit, CcmK1 | | 分子名称: | Carbon dioxide-concentrating mechanism protein ccmK homolog 1, SULFATE ION | | 著者 | Tanaka, S, Sawaya, M.R, Yeates, T.O. | | 登録日 | 2007-12-13 | | 公開日 | 2008-03-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Atomic-level models of the bacterial carboxysome shell.
Science, 319, 2008
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6UMV
 | | Human apo PD-1 double mutant | | 分子名称: | CHLORIDE ION, Programmed cell death protein 1 | | 著者 | Tang, S, Kim, P.S. | | 登録日 | 2019-10-10 | | 公開日 | 2019-11-27 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.424 Å) | | 主引用文献 | A high-affinity human PD-1/PD-L2 complex informs avenues for small-molecule immune checkpoint drug discovery.
Proc.Natl.Acad.Sci.USA, 116, 2019
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5WRJ
 | | Crystal structure of human tyrosylprotein sulfotransferase-1 complexed with PAP and gastrin peptide | | 分子名称: | ADENOSINE-3'-5'-DIPHOSPHATE, MAGNESIUM ION, Protein-tyrosine sulfotransferase 1, ... | | 著者 | Tanaka, S, Nishiyori, T, Kojo, H, Otsubo, R, Kakuta, Y. | | 登録日 | 2016-12-02 | | 公開日 | 2017-09-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Structural basis for the broad substrate specificity of the human tyrosylprotein sulfotransferase-1.
Sci Rep, 7, 2017
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5WRI
 | | Crystal structure of human tyrosylprotein sulfotransferase-1 complexed with PAP and C4 peptide | | 分子名称: | ADENOSINE-3'-5'-DIPHOSPHATE, ASP-PHE-GLU-ASP-TYR-GLU-PHE-ASP, GLYCEROL, ... | | 著者 | Tanaka, S, Nishiyori, T, Kojo, H, Otsubo, R, Kakuta, Y. | | 登録日 | 2016-12-02 | | 公開日 | 2017-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural basis for the broad substrate specificity of the human tyrosylprotein sulfotransferase-1.
Sci Rep, 7, 2017
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1MNM
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8HIT
 | | Crystal structure of anti-CTLA-4 humanized IgG1 MAb--JS007 in complex with human CTLA-4 | | 分子名称: | Cytotoxic T-lymphocyte protein 4, JS007-VH, JS007-VL | | 著者 | Tan, S, Shi, Y, Wang, Q, Gao, G.F, Guan, J, Chai, Y, Qi, J. | | 登録日 | 2022-11-21 | | 公開日 | 2023-02-01 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Characterization of the high-affinity anti-CTLA-4 monoclonal antibody JS007 for immune checkpoint therapy of cancer.
Mabs, 15, 2023
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1YTF
 | | YEAST TFIIA/TBP/DNA COMPLEX | | 分子名称: | DNA (5'-D(*GP*TP*TP*TP*TP*AP*TP*AP*TP*AP*CP*AP*TP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*AP*TP*GP*TP*AP*TP*AP*TP*AP*AP*AP*AP*C)-3'), PROTEIN (TATA BINDING PROTEIN (TBP)), ... | | 著者 | Tan, S, Hunziker, Y, Sargent, D.F, Richmond, T.J. | | 登録日 | 1996-04-05 | | 公開日 | 1996-06-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of a yeast TFIIA/TBP/DNA complex.
Nature, 381, 1996
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5XJ4
 | | Complex structure of durvalumab-scFv/PD-L1 | | 分子名称: | Programmed cell death 1 ligand 1, durvalumab-VH, durvalumab-VL | | 著者 | Tan, S, Liu, K, Chai, Y, Gao, G.F, Qi, J. | | 登録日 | 2017-04-29 | | 公開日 | 2018-04-25 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Distinct PD-L1 binding characteristics of therapeutic monoclonal antibody durvalumab
Protein Cell, 9, 2018
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3MN8
 | | Structure of Drosophila melanogaster carboxypeptidase D isoform 1B short | | 分子名称: | (2-GUANIDINOETHYLMERCAPTO)SUCCINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | | 著者 | Tanco, S, Arolas, J.L, Guevara, T, Lorenzo, J, Aviles, F.X, Gomis-Ruth, F.X. | | 登録日 | 2010-04-21 | | 公開日 | 2010-07-28 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure-Function Analysis of the Short Splicing Variant Carboxypeptidase Encoded by Drosophila melanogaster silver.
J.Mol.Biol., 401, 2010
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8KDX
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7S0B
 | | Structure of the SARS-CoV-2 RBD in complex with neutralizing antibody N-612-056 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, N-612-056 Fab Heavy Chain, N-612-056 Light Chain, ... | | 著者 | Tanaka, S, Barnes, C.O, Bjorkman, P.J. | | 登録日 | 2021-08-30 | | 公開日 | 2021-10-06 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Rapid identification of neutralizing antibodies against SARS-CoV-2 variants by mRNA display.
Cell Rep, 38, 2022
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6UMT
 | | High-affinity human PD-1 PD-L2 complex | | 分子名称: | MAGNESIUM ION, Programmed cell death 1 ligand 2, Programmed cell death protein 1 | | 著者 | Tang, S, Kim, P.S. | | 登録日 | 2019-10-10 | | 公開日 | 2019-11-27 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.986 Å) | | 主引用文献 | A high-affinity human PD-1/PD-L2 complex informs avenues for small-molecule immune checkpoint drug discovery.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6UMU
 | | Human apo PD-1 triple mutant | | 分子名称: | CHLORIDE ION, Programmed cell death protein 1 | | 著者 | Tang, S, Kim, P.S. | | 登録日 | 2019-10-10 | | 公開日 | 2019-11-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.183 Å) | | 主引用文献 | A high-affinity human PD-1/PD-L2 complex informs avenues for small-molecule immune checkpoint drug discovery.
Proc.Natl.Acad.Sci.USA, 116, 2019
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7OT4
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2E1P
 | | Crystal structure of pro-Tk-subtilisin | | 分子名称: | CALCIUM ION, Tk-subtilisin | | 著者 | Tanaka, S, Saito, K, Chon, H, Matsumura, H, Koga, Y, Takano, K, Kanaya, S. | | 登録日 | 2006-10-27 | | 公開日 | 2007-01-16 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of unautoprocessed precursor of subtilisin from a hyperthermophilic archaeon: evidence for Ca2+-induced folding
J.Biol.Chem., 282, 2007
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6PER
 | | Crystal Structure of Ligand-Free iSeroSnFR | | 分子名称: | 1,2-ETHANEDIOL, iSeroSnFR, a soluble, ... | | 著者 | Hartanto, S, Tian, L, Fisher, A.J. | | 登録日 | 2019-06-20 | | 公開日 | 2020-06-24 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning.
Cell, 183, 2020
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7UX0
 | | Human Sperm TMEM95 Ectodomain | | 分子名称: | Sperm-egg fusion protein TMEM95, TRIETHYLENE GLYCOL, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Tang, S, Kim, P.S. | | 登録日 | 2022-05-04 | | 公開日 | 2022-10-12 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Human sperm TMEM95 binds eggs and facilitates membrane fusion.
Proc.Natl.Acad.Sci.USA, 119, 2022
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8JP6
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8JPG
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8JP7
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8JP8
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8JP9
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8JP5
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