1YTF
YEAST TFIIA/TBP/DNA COMPLEX
Summary for 1YTF
Entry DOI | 10.2210/pdb1ytf/pdb |
Descriptor | DNA (5'-D(*TP*GP*TP*AP*TP*GP*TP*AP*TP*AP*TP*AP*AP*AP*AP*C)-3'), DNA (5'-D(*GP*TP*TP*TP*TP*AP*TP*AP*TP*AP*CP*AP*TP*AP*CP*A)-3'), PROTEIN (TATA BINDING PROTEIN (TBP)), ... (6 entities in total) |
Functional Keywords | transcription regulation, dna, complex, transcription-dna complex, transcription/dna |
Biological source | Saccharomyces cerevisiae (baker's yeast) More |
Cellular location | Nucleus: P13393 Cytoplasm: P32773 P32773 P32774 |
Total number of polymer chains | 6 |
Total formula weight | 58305.47 |
Authors | Tan, S.,Hunziker, Y.,Sargent, D.F.,Richmond, T.J. (deposition date: 1996-04-05, release date: 1996-06-20, Last modification date: 2024-02-14) |
Primary citation | Tan, S.,Hunziker, Y.,Sargent, D.F.,Richmond, T.J. Crystal structure of a yeast TFIIA/TBP/DNA complex. Nature, 381:127-134, 1996 Cited by PubMed Abstract: The X-ray crystal structure of the transcription factor IIA (TFIIA) in complex with the TATA-box-binding protein (TBP) and TATA-element DNA is presented at 2.5 A resolution. TFIIA is composed of a beta-barrel and a four-helix bundle motif that together have a boot-like appearance. The beta-barrel extends the TBP beta-sheet and bridges over the DNA major groove immediately upstream of the TATA box. The four-helix bundle contributes substantially to the surface of the complex available for interaction with additional transcription factors. PubMed: 8610010DOI: 10.1038/381127a0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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